The renal epithelial sodium channel: Genetic heterogeneity and implications for the treatment of high blood pressure

Current Pharmaceutical Design

Volumn 12, Issue 18, 2006, Pages 2221-2234

  Sagnella, G A ^a   Swift, P A ^b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Afro Caribbeans; Aldosterone; Amiloride; Channel activating protease (CAP); Hypertension; Neural cell expressed developmentally down regulated 4 (Nedd4)

Indexed keywords

ALDOSTERONE; AMILORIDE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; GLUCOCORTICOID; LOOP DIURETIC AGENT; PROSTASIN; PROTEIN SUBUNIT; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SPIRONOLACTONE; THIAZIDE DIURETIC AGENT; UBIQUITIN PROTEIN LIGASE NEDD4;

ANTIHYPERTENSIVE ACTIVITY; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; BLOOD VOLUME; CARDIOVASCULAR DISEASE; CHEMICAL ANALYSIS; CLINICAL TRIAL; DISEASE ASSOCIATION; DRUG BINDING SITE; DRUG TARGETING; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC CODE; GENETIC HETEROGENEITY; GENETIC VARIABILITY; HUMAN; HYPOKALEMIA; KIDNEY EPITHELIUM; LIDDLE SYNDROME; MORBIDITY; MORTALITY; MUTATIONAL ANALYSIS; NEPHRON; NONHUMAN; PATHOPHYSIOLOGY; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PSEUDOHYPOALDOSTERONISM; REVIEW; SODIUM ABSORPTION; SODIUM BALANCE;

ALDOSTERONE; AMILORIDE; ANIMALS; BLOOD PRESSURE; EPITHELIAL SODIUM CHANNEL; HUMANS; HYPERTENSION; IMMEDIATE-EARLY PROTEINS; ION CHANNEL GATING; MUTATION; NEPHRONS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; UBIQUITIN-PROTEIN LIGASES;

EID: 33745144636     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161206777585157     Document Type: Review

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