Evaluation of selected polymorphisms of the Mendelian hypertensive disease genes in the Japanese population

Hypertension Research

Volumn 24, Issue 5, 2001, Pages 515-521

  Sugiyama, T ^a   Kato, N ^a   Ishinaga, Y ^a   Yamori, Y ^a   Yazaki, Y ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Essential hypertension; Genetics; Mendelian inheritance; Single nucleotide polymorphism

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; ANTIHYPERTENSIVE AGENT; EPITHELIAL SODIUM CHANNEL PROTEIN; EPITHELIAL SODIUM CHANNEL PROTEIN ALPHA; GENE PRODUCT; MINERALOCORTICOID RECEPTOR; RENIN; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG; WATER;

ADULT; AGED; ALDOSTERONE BLOOD LEVEL; ARTICLE; BIOCHEMISTRY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE SEVERITY; ESSENTIAL HYPERTENSION; ETHNIC DIFFERENCE; EVALUATION; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HOMEOSTASIS; HUMAN; HYPERTENSION; JAPAN; MAJOR CLINICAL STUDY; MALE; MENDELIAN HYPERTENSIVE DISEASE; MOLECULAR GENETICS; MULTIVARIATE ANALYSIS; ONSET AGE; PLASMA RENIN ACTIVITY; PREVALENCE; SEQUENCE ANALYSIS;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2; AGED; EPITHELIAL SODIUM CHANNEL; FEMALE; GENOTYPE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; HYPERTENSION; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, MINERALOCORTICOID; SODIUM CHANNELS;

EID: 0035163225     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.24.515     Document Type: Article

References (33)

1. Molecular genetics of human blood pressure variation
2. A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
3. Liddle's syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
4. Hypertension caused by a truncated epithelial sodium channel gamma subunit: Genetic heterogeneity of Liddle syndrome
5. Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
6. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy
7. Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21
8. Seven lessons from two candidate genes in human essential hypertension: Angiotensinogen and epithelial sodium channel
9. Genetically complex cardiovascular traits: Origins, problems, and potential solutions
10. Lack of sex-specific effects on the association between angiotensin-converting enzyme gene polymorphism and hypertension in Japanese
11. Angiotensinogen and angiotensin-converting enzyme genotypes, and day and night blood pressures in elderly Japanese hypertensives
12. Renin gene MboI dimorphism is a discriminator for hypertension in hyperlipidaemic subjects
13. Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension
14. Polymorphism of alpha-adducin in Japanese patients with essential hypertension
15. + channel is made of three homologous sub-units
16. Lack of mutations in epithelial sodium channel beta-subunit gene in human subjects with hypertension
17. A novel variant of the beta-subunit of the amiloride-sensitive sodium channel in African Americans
18. Association of hypertension with T594M mutation in beta subunit of epithelial sodium channels in black people resident in London
19. Mutations and variants of the epithelial sodium channel gene in Liddle's syndrome and primary hypertension
20. + channel in essential hypertension
21. Genetic variants in the epithelial sodium channel in relation to aldosterone and potassium excretion and risk for hypertension
22. + channel in essential hypertension
23. Japanese individuals do not harbor the T594M mutation but do have the P592S mutation in the C-terminus of the beta-subunit of the epithelial sodium channel: The Ohasama study
24. Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I
25. Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess
26. Comprehensive analysis of the renin-angiotensin gene polymorphisms with relation to hypertension in the Japanese
27. On estimating the relation between blood group and disease
28. Inappropriate elevation of the aldosterone/plasma renin activity ratio in hypertensive patients with increases of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone: A subtype of essential hypertension?
29. Structural analysis and evaluation of the 11 beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) gene in human essential hypertension
30. A new polymorphic restriction site in the human 11 beta-hydroxysteroid dehydrogenase type 2 gene
31. A genetic defect resulting in mild low-renin hypertension
32. Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess
33. Apparent mineralocorticoid excess: Type I and type II