Association of hypertension with T594M mutation in β subunit of epithelial sodium channels in black people resident in London

Lancet

Volumn 351, Issue 9113, 1998, Pages 1388-1392

  Baker, E H ^a   Dong, Y B ^a   Sagnella, G A ^a   Rothwell, M ^a   Onipinla, A K ^a   Markandu, N D ^a   Cappuccio, F P ^a   Cook, D G ^a   Persu, A ^b   Corvol, P ^b   Jeunemaitre, X ^b   Carter, N D ^a   MacGregor, G A ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b PSL Research University   (France)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN; SODIUM CHANNEL;

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA SEQUENCE; ESSENTIAL HYPERTENSION; EXON; FEMALE; GENE MUTATION; GENETIC SCREENING; HUMAN; HYPERTENSION; KIDNEY TUBULE ABSORPTION; LIDDLE SYNDROME; MAJOR CLINICAL STUDY; MALE; NEGRO; PLASMA RENIN ACTIVITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE STRAND CONFORMATION POLYMORPHISM; UNITED KINGDOM;

EID: 0032499488     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(97)07306-6     Document Type: Article

References (19)

1. 1 deWardener HE, MacGregor GA. The natriuretic hormone and essential hypertension. Lancet 1982; i: 1450-54.
2. 2 Curtis JJ; Luke RG, Dustan HP, et al. Remission of essential hypertension after renal transplantation. N Engl J Med 1983; 309: 1009-15.
3. 3 Lifton RP. Molecular genetics of human blood pressure variation. Science 1996; 272: 676-80.
4. 4 Shimkets RA, Warnock DG, Bositis CM, et al. Liddle's syndrome: heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel. Cell 1994; 79: 407-14.
5. 5 Hansson JH, Nelson-Williams C, Suzuki H, et al. Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle's syndrome. Nat Genet 1995; 11: 76-82.
6. 6 Liddle GW, Bledsoe T, Coppage WS Jr. A familial renal disorder simultating primary aldosteronism but with negligible aldosterone secretion. Trans Assoc Am Phys 1963; 76: 199-213.
7. + channel in essential hypertension. Hypertension 1998; (in press).
8. 8 Schild L, Canessa CM, Shimkets RA, Gautschi I, Lifton RP, Rossier BC. A mutation in the epithelial sodium channel causing Liddle disease increases sodium channel activity in the Xenopus laevis oocyte expression system. Proc Natl Acad Sci USA 1995; 92: 5699-703.
9. 9 Su YR, Rutkowski MP, Klanke CA, et al. A novel variant of the β-subunit of the amiloride-sensitive sodium channel in African Americans. J Am Soc Nephrol 1996; 7: 2543-49.
10. 10 Cappuccio FP, Cook DG, Atkinson RW, Strazzullo P. Prevalence, detection and management of cardiovascular risk factors in different ethnic groups in South London. Heart 1997; 78: 555-63.
11. 11 George CF, Lewis PJ, Petrie A. Clinical experience with use of ultrasound sphygmomanometer. Br Heart J 1975; 37: 804-07.
12. 12 Technique of blood pressure measurement. J Hypertens 1985; 3: 293.
13. 13 Roulston JE, MacGregor GA. Measurements of plasma renin activity by radioimmunoassay after prolonged cold storage. Clin Chem Acta 1978; 88: 45-48.
14. 14 James VHT, Wilson GA. Assays of drugs and other trace compounds in biological fluids. In: Reid E, ed. Methodological Development in Biochemistry, vol 5. Amsterdam: Elsevier, 1976: 149-58.
15. 15 Voilley N, Bassilana F, Mignon C, et al. Cloning, chromosomal localisation and physical linkage of the β and γ subunits (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel. Genomics 1995; 28 560-65.
16. 16 Sammons DW, Adams LD, Nishizawe EE. Ultrasensitive silver-based colour staining of polypeptides in polyacrylamide gels. Electrophoresis 1991; 2: 135-41.
17. 17 Botero-Velez M, Curtis JJ, Warnock DG. Liddle's syndrome revisited - a disorder of sodium reabsorption in the distal tuble. N Engl J Med 1994; 330: 178-81.
18. 18 Chang H, Fujita T. Lack of mutations in epithelial sodium channel β subunit gene in human subjects with hypertension. J Hypertens 1996; 14: 1417-19.
19. 19 Munroe PB, Strautnieks SS, Farrall M, et al. Investigation of the epithelial sodium channel gene (hENaC) as a candidate gene for essential hypertension in African Caribbeans. Am J Hypertens 1997; 10: 5A.