WAY-100635 antagonist-induced plasticity of 5-HT1A receptors: Regulatory differences between a stable cell line and an in vivo native system

Journal of Neurochemistry

Volumn 98, Issue 1, 2006, Pages 134-145

  Khawaja, Xavier Z ^a,b   Smith, Deborah L ^a   Nawoschik, Stanley P ^a   Zhang, Jean ^a   Dunlop, John ^a   Dilks, Daniel W ^a   Olsen, Michael ^a   Schechter, Lee E ^a  

^a PFIZER INC   (United States)

^b CN8000   (United States)

Author keywords

Autoradiography; CHO K1 cells; Human 5 HT1A receptor; Receptor internalization; WAY 100635

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CELL SURFACE RECEPTOR; CYCLIC AMP; FORSKOLIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PERTUSSIS TOXIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN AGONIST; TRITIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CALCIUM MOBILIZATION; CELL LINE; CELL TRANSPORT; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOCYTOSIS; FEMALE; MALE; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BRAIN; BRAIN MAPPING; CALCIUM; CHO CELLS; CRICETINAE; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG INTERACTIONS; FORSKOLIN; HUMANS; MALE; NEURONAL PLASTICITY; PIPERAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; TRITIUM;

CRICETULUS GRISEUS;

EID: 33745076212     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03883.x     Document Type: Article

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