Intrathecally infused antibodies against Nogo-A penetrate the CNS and downregulate the endogenous neurite growth inhibitor Nogo-A

Molecular and Cellular Neuroscience

Volumn 32, Issue 1-2, 2006, Pages 161-173

  Weinmann, Oliver ^a   Schnell, Lisa ^a   Ghosh, Arko ^a   Montani, Laura ^a   Wiessner, Christoph ^b   Wannier, Thierry ^c   Rouiller, Eric ^c   Mir, Anis ^b   Schwab, Martin E ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CATHEPSIN D; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; PROTEIN NOGO A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ORGANELLE; CELL SURFACE; CELL TRANSPORT; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CONTROLLED STUDY; DOWN REGULATION; DRUG INFUSION; DRUG PENETRATION; DRUG TRANSPORT; EMBRYO; FEMALE; GROWTH INHIBITION; LYSOSOME; MALE; MONKEY; NERVE CELL CULTURE; NERVE FIBER GROWTH; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; SPINAL CORD NERVE CELL;

ANIMALS; ANTIBODIES; CELLS, CULTURED; CEREBROSPINAL FLUID; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOCYTOSIS; FEMALE; GROWTH INHIBITORS; INJECTIONS, SPINAL; MACACA FASCICULARIS; MALE; MYELIN PROTEINS; NERVE REGENERATION; NEURONS; OLIGODENDROGLIA; RATS; RATS, INBRED F344; RATS, INBRED LEW; SPINAL CORD; SPINAL CORD INJURIES; SUBARACHNOID SPACE;

EID: 33744990155     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2006.03.007     Document Type: Article

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