Antibody to epitope tag induces internalization of human muscarinic subtype 1 receptor

Journal of Neurochemistry

Volumn 70, Issue 1, 1998, Pages 113-119

  Tolbert, Lara M ^a   Lameh, Jelveh ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Clathrin; Endocytosis; G protein coupled receptor; Receptor regulation; Trafficking

Indexed keywords

ATROPINE; CARBACHOL; CLATHRIN; EPITOPE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUSCARINIC M1 RECEPTOR; PHOSPHATIDYLINOSITIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; DIMERIZATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; RECEPTOR BLOCKING; SECOND MESSENGER;

EID: 0031983450     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70010113.x     Document Type: Article

References (25)

1. Arden J. R. and Lameh J. (1996) Agonist-induced internalization of human m1 muscarinic receptor mutants: immunofluorescence confocal microscopy. Proc. West. Pharmacol. Soc. 39, 51-53.
2. Arden J. R., Segredo V., Wang Z., Lameh J., and Sadée W. (1995) Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged μ-opioid receptor expressed in HEK 293 cells. J. Neurochem. 65, 1636-1645.
3. Ashworth R., Yu R., Nelson E. J., Dermer S., Gershengorn M. C., and Hinkle P. M. (1995) Visualization of the thyrotropin-releasing hormone receptor and its ligand during endocytosis and recycling. Proc. Natl. Acad. Sci. USA 92, 512-516.
4. Bogatkewitsch G. S., Lenz W., Jakobs K. H., and van Koppen C. J. (1996) Receptor internalization delays m4 muscarinic acetylcholine receptor resensitization at the plasma membrane. Mol. Pharmacol. 50, 424-429.
5. Ferguson S. S., Downey W. E. III, Colapietro A. M., Barak L. S., Menard L., and Caron M. G. (1996) Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271, 363-366.
6. Ghinea N., Vu Hai M. T., Groyer-Picard M. T., Houllier A., Schoevaert D., and Milgrom E. (1992) Pathways of internalization of the hCG/LH receptor: immunoelectron microscopic studies in Leydig cells and transfected L-cells. J. Cell Biol. 118, 1347-1358.
7. Huang Z., Chen Y., and Nissenson R. A. (1995) The cytoplasmic tail of the G-protein-coupled receptor for parathyroid hormone and parathyroid hormone-related protein contains positive and negative signals for endocytosis. J. Biol. Chem. 270, 151-156.
8. Hunyady L., Baukal A. J., Balla T., and Catt K. J. (1994) Independence of type I angiotensin II receptor endocytosis from G protein coupling and signal transduction. J. Biol. Chem. 269, 24798-24804.
9. Keith D. E., Murray S. R., Zak P. A., Chu P. C., Lissin D. V., Kang L., Evans C. J., and von Zastrow M. (1996) Morphine activates opioid receptors without causing their rapid internalization. J. Biol. Chem. 271, 19021-19024.
10. Moro O., Lameh J., Högger P., and Sadée W. (1993) Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling. J. Biol. Chem. 268, 22273-22278.
11. Moro O., Shockley M. S., Lameh J., and Sadée W. (1994) Overlapping multi-site domains of the muscarinic cholinergic Hml receptor involved in signal transduction and sequestration. J. Biol. Chem. 269, 6651-6655.
12. Petrou C., Chen L., and Tashjian A. H. Jr. (1997) A receptor-G protein coupling-independent step in the internalization of the thyrotropin-releasing hormone receptor. J. Biol. Chem. 272, 2326-2333.
13. 2-adrenergic receptors permit receptor resensitization. Mol. Pharmacol. 47, 666-676.
14. Roettger B. F., Ghanekar D., Toledo C., Yingling J., Pinon D., and Miller L. J. (1997) Antagonist-stimulated internalization of the G protein-coupled cholecystokinin receptor. Mol. Pharmacol. 51, 357-362.
15. Saito Y., Teshima R., Yamazaki T., Ikebuchi H., and Sawada J. (1994) Ligand-induced internalization and phosphorylation-dependent degradation of growth hormone receptor in human IM-9 cells. Mol. Cell. Endocrinol. 106, 67-74.
16. Sandvig K., Olsnes S., Petersen O. W., and van Deurs B. (1987) Acidification of the cytosol inhibits endocytosis from coated pits. J. Cell Biol. 105, 679-689.
17. Sargent P. B. (1994) Double-label immunofluorescence with laser scanning confocal microscope using cyanine dyes. Neuroimage 1, 288-295.
18. Segredo V., Burford N. T., Lameh J., and Sadée W. (1997) A constitutively internalizing and recycling mutant of the μ-opioid receptor. J. Neurochem. 68, 2395-2404.
19. Shockley M. S., Burford N. T., Sadée W., and Lameh J. (1997) Residues specifically involved in down-regulation but not internalization of the m1 muscarinic acetylcholine receptor. J. Neurochem. 68, 601-609.
20. Slowiejko D. M., McEwen E. L., Ernst S. A., and Fisher S. K. (1996) Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed. J. Neurochem. 66, 186-196.
21. Smart E. J., Foster D. C., Ying Y.-S., Kamen B. A., and Anderson R. G. W. (1994) Protein kinase C activators inhibit receptor-mediated potocytosis by preventing internalization of caveolae. J. Cell Biol. 124, 307-313.
22. HER2 in the human lung adenocarcinoma cell line Calu-3 requires bivalency. Cancer Immimol. Immunother. 36, 397-402.
23. Thompson A. K., Mostafapour S. P., Denlinger L. C., Bleasdale J. E., and Fisher S. K. (1991) The aminosteroid U-73122 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. J. Biol. Chem. 266, 23856-23862.
24. Tolbert L. M. and Lameh J. (1996) Human muscarinic cholinergic receptor Hml internalizes via clathrin-coated vesicles. J. Biol. Chem. 271, 17335-17342.
25. Zhang J., Ferguson S. S. G., Barak L. S., Menard L., and Caron M. G. (1996) Dynamin and β-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization. J. Biol. Chem. 271, 18302-18305.