Increased apoptosis of CD20+ IgA+ B cells is the basis for IgA deficiency: The molecular mechanism for correction in vitro by IL-10 and CD40L

Journal of Clinical Immunology

Volumn 26, Issue 2, 2006, Pages 113-125

  Husain, Zaheed ^a,c   Holodick, Nichol ^a   Day, Caitlin ^a   Szymanski, Irma ^b   Alper, Chester A ^a,c  

^a CENTER FOR BLOOD RESEARCH   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Caspase 1; IgA deficiency; Immunodeficiency diseases

Indexed keywords

CASPASE INHIBITOR; CD19 ANTIGEN; CD20 ANTIGEN; CD40 LIGAND; COMPLEMENTARY DNA; IMMUNOGLOBULIN A; INHIBITOR OF APOPTOSIS PROTEIN 2; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; SECRETORY IMMUNOGLOBULIN; TETANUS TOXOID;

ADULT; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL PROTECTION; CELL SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE LOSS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN A DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCING CELL; IMMUNOGLOBULIN PRODUCTION; MALE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; UPREGULATION;

ADULT; AGED; ANIMALS; ANTIGENS, CD19; ANTIGENS, CD20; APOPTOSIS; B-LYMPHOCYTES; CASPASE 1; CD40 LIGAND; FEMALE; GENE EXPRESSION; HUMANS; IGA DEFICIENCY; IMMUNOGLOBULIN A; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-18; MALE; MICE; MIDDLE AGED; NIH 3T3 CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGOPEPTIDES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33744979093     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-006-9001-y     Document Type: Article

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