The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women

American Journal of Human Genetics

Volumn 60, Issue 3, 1997, Pages 505-514

  Abeliovich, Dvorah ^a   Kaduri, Luna ^a   Lerer, Israela ^a   Weinberg, Naomi ^a   Amir, Gail ^a   Sagi, Michal ^a   Zlotogora, Joël ^a   Heching, Norman ^a   Peretz, Tamar ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CANCER INCIDENCE; FAMILY HISTORY; FEMALE; GENE DELETION; GENE MUTATION; HUMAN; JEW; MAJOR CLINICAL STUDY; ONSET AGE; OVARY CANCER; PRIORITY JOURNAL;

ADULT; AGED; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; FEMALE; FOUNDER EFFECT; HAPLOTYPES; HETEROZYGOTE; HUMANS; IRAQ; JEWS; MALE; MIDDLE AGED; MORBIDITY; MUTAGENESIS, INSERTIONAL; MUTATION; NEOPLASM PROTEINS; NEOPLASMS, SECOND PRIMARY; OVARIAN NEOPLASMS; PEDIGREE; RISK FACTORS; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

EID: 0031035359     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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