-
1
-
-
0031616132
-
The IRS-signaling system: A network of docking proteins that mediate insulin and cytokine action
-
White MF. The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action. Recent Prog Horm Res 1998;53:119-38.
-
(1998)
Recent Prog Horm Res
, vol.53
, pp. 119-138
-
-
White, M.F.1
-
2
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto H, Kadowaki T, Tobe K, et al. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 1994;372:182-6.
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
-
3
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki E, Lipes MA, Patti ME, et al. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 1994;372:186-90.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
-
4
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
Withers DJ, Gutierrez JS, Towery H, et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 1998;391: 900-4.
-
(1998)
Nature
, vol.391
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
-
5
-
-
0040973209
-
Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells
-
Bruning JC, Winnay J, Cheatham B, Kahn CR. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells. Mol Cell Biol 1997;17:1513-21.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1513-1521
-
-
Bruning, J.C.1
Winnay, J.2
Cheatham, B.3
Kahn, C.R.4
-
6
-
-
0028124504
-
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation
-
Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation. Mol Cell Biol 1994;14:6674-82.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6674-6682
-
-
Noguchi, T.1
Matozaki, T.2
Horita, K.3
Fujioka, Y.4
Kasuga, M.5
-
7
-
-
0033515459
-
Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway
-
Li J, DeFea K, Roth RA. Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway. J Biol Chem 1999;274: 9351-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 9351-9356
-
-
Li, J.1
DeFea, K.2
Roth, R.A.3
-
8
-
-
0027202202
-
Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II
-
Tanasijevic MJ, Myers MG, Jr., Thoma RS, Crimmins DL, White MF, Sacks DB. Phosphorylation of the insulin receptor substrate IRS-1 by casein kinase II. J Biol Chem 1993;268:18157-66.
-
(1993)
J Biol Chem
, vol.268
, pp. 18157-18166
-
-
Tanasijevic, M.J.1
Myers Jr., M.G.2
Thoma, R.S.3
Crimmins, D.L.4
White, M.F.5
Sacks, D.B.6
-
9
-
-
0031465447
-
Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
-
De Fea K, Roth RA. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J Biol Chem 1997;272: 31400-6.
-
(1997)
J Biol Chem
, vol.272
, pp. 31400-31406
-
-
De Fea, K.1
Roth, R.A.2
-
10
-
-
0034708832
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
-
Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000;275:9047-54.
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
11
-
-
1542616960
-
Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation
-
Carlson CJ, White MF, Rondinone CM. Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation. Biochem Biophys Res Commun 2004;316: 533-9.
-
(2004)
Biochem Biophys Res Commun
, vol.316
, pp. 533-539
-
-
Carlson, C.J.1
White, M.F.2
Rondinone, C.M.3
-
12
-
-
0028018858
-
The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin
-
Lam K, Carpenter CL, Ruderman NB, Friel JC, Kelly KL. The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin. J Biol Chem 1994;269: 20648-52.
-
(1994)
J Biol Chem
, vol.269
, pp. 20648-20652
-
-
Lam, K.1
Carpenter, C.L.2
Ruderman, N.B.3
Friel, J.C.4
Kelly, K.L.5
-
13
-
-
0035793592
-
Protein kinase C-ζ phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin
-
Ravichandran LV Esposito DL, Chen J, Quon MJ. Protein kinase C-ζ phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. J Biol Chem 2001;276:3543-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 3543-3549
-
-
Ravichandran, L.V.1
Esposito, D.L.2
Chen, J.3
Quon, M.J.4
-
14
-
-
0037155132
-
Active Rho kinase (ROK-α) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells
-
Begum N, Sandu OA, Ito M, Lohmann SM, Smolenski A. Active Rho kinase (ROK-α) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J Biol Chem 2002;277: 6214-22.
-
(2002)
J Biol Chem
, vol.277
, pp. 6214-6222
-
-
Begum, N.1
Sandu, O.A.2
Ito, M.3
Lohmann, S.M.4
Smolenski, A.5
-
15
-
-
0033214461
-
Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function
-
Paz K, Liu YF, Shorer H, et al. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. J Biol Chem 1999; 274:28816-22.
-
(1999)
J Biol Chem
, vol.274
, pp. 28816-28822
-
-
Paz, K.1
Liu, Y.F.2
Shorer, H.3
-
16
-
-
13844272212
-
Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation
-
Kaiser C, James SR. Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation. BMC Biol 2004;2:23.
-
(2004)
BMC Biol
, vol.2
, pp. 23
-
-
Kaiser, C.1
James, S.R.2
-
17
-
-
0033982719
-
Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3′-kinase inhibition
-
Lee AV, Gooch JL, Oesterreich S, Guler RL, Yee D. Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3′-kinase inhibition. Mol Cell Biol 2000;20:1489-96.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1489-1496
-
-
Lee, A.V.1
Gooch, J.L.2
Oesterreich, S.3
Guler, R.L.4
Yee, D.5
-
18
-
-
0000085132
-
Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway
-
Sun XJ, Goldberg JL, Qiao LY, Mitchell JJ. Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway. Diabetes 1999;48:1359-64.
-
(1999)
Diabetes
, vol.48
, pp. 1359-1364
-
-
Sun, X.J.1
Goldberg, J.L.2
Qiao, L.Y.3
Mitchell, J.J.4
-
19
-
-
2942554944
-
Caspase-mediated cleavage of insulin receptor substrate
-
Green KA, Naylor MJ, Lowe ET, Wang P, Marshman E, Streuli CH. Caspase-mediated cleavage of insulin receptor substrate. J Biol Chem 2004;279:25149-56.
-
(2004)
J Biol Chem
, vol.279
, pp. 25149-25156
-
-
Green, K.A.1
Naylor, M.J.2
Lowe, E.T.3
Wang, P.4
Marshman, E.5
Streuli, C.H.6
-
20
-
-
0027421453
-
The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro
-
Smith LK, Bradshaw M, Croall DE, Garner CW. The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro. Biochem Biophys Res Commun 1993;196:767-72.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 767-772
-
-
Smith, L.K.1
Bradshaw, M.2
Croall, D.E.3
Garner, C.W.4
-
21
-
-
0242574322
-
Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2
-
Cui X, Lazard Z, Zhang P, Hopp TA, Lee AV. Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2. Oncogene 2003;22:6937-41.
-
(2003)
Oncogene
, vol.22
, pp. 6937-6941
-
-
Cui, X.1
Lazard, Z.2
Zhang, P.3
Hopp, T.A.4
Lee, A.V.5
-
22
-
-
0033305004
-
Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
-
Lee AV, Jackson JG, Gooch JL, et al. Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 1999;13:787-96.
-
(1999)
Mol Endocrinol
, vol.13
, pp. 787-796
-
-
Lee, A.V.1
Jackson, J.G.2
Gooch, J.L.3
-
23
-
-
0034967344
-
Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: New insights into their synergistic effects
-
Dupont J, Le Roith D. Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects. Mol Pathol 2001;54:149-54.
-
(2001)
Mol Pathol
, vol.54
, pp. 149-154
-
-
Dupont, J.1
Le Roith, D.2
-
24
-
-
0034624106
-
Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression
-
Lebrun P, Baron V, Hauck CR, Schlaepfer DD, Van Obberghen E. Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression. J Biol Chem 2000;275:38371-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 38371-38377
-
-
Lebrun, P.1
Baron, V.2
Hauck, C.R.3
Schlaepfer, D.D.4
Van Obberghen, E.5
-
25
-
-
0029029137
-
Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells
-
Ram TG, Kokeny KE, Dilts CA, Ethier SP. Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells. J Cell Physiol 1995;163:589-96.
-
(1995)
J Cell Physiol
, vol.163
, pp. 589-596
-
-
Ram, T.G.1
Kokeny, K.E.2
Dilts, C.A.3
Ethier, S.P.4
-
26
-
-
0036231180
-
Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells
-
Stull MA, Richert MM, Loladze AV, Wood TL. Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells. Endocrinology 2002;143:1872-9.
-
(2002)
Endocrinology
, vol.143
, pp. 1872-1879
-
-
Stull, M.A.1
Richert, M.M.2
Loladze, A.V.3
Wood, T.L.4
-
28
-
-
0034698105
-
Insulin-like growth factor I-mediated degradation of insulin receptor substrate-I is inhibited by epidermal growth factor in prostate epithelial cells
-
Zhang H, Hoff H, Sell C. Insulin-like growth factor I-mediated degradation of insulin receptor substrate-I is inhibited by epidermal growth factor in prostate epithelial cells. J Biol Chem 2000;275:22558-62.
-
(2000)
J Biol Chem
, vol.275
, pp. 22558-22562
-
-
Zhang, H.1
Hoff, H.2
Sell, C.3
-
29
-
-
0037385522
-
Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer
-
Cui X, Zhang P, Deng W, et al. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer. Mol Endocrinol 2003;17: 575-88.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 575-588
-
-
Cui, X.1
Zhang, P.2
Deng, W.3
-
30
-
-
0037119423
-
Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype
-
Rennefahrt UE, Illert B, Kerkhoff E, Troppmair J, Rapp UR. Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype. J Biol Chem 2002;277:29510-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 29510-29518
-
-
Rennefahrt, U.E.1
Illert, B.2
Kerkhoff, E.3
Troppmair, J.4
Rapp, U.R.5
-
31
-
-
0030802419
-
A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis
-
Olive M, Krylov D, Echlin DR, Gardner K, Taparowsky E, Vinson C. A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis. J Biol Chem 1997;272:18586-94.
-
(1997)
J Biol Chem
, vol.272
, pp. 18586-18594
-
-
Olive, M.1
Krylov, D.2
Echlin, D.R.3
Gardner, K.4
Taparowsky, E.5
Vinson, C.6
-
32
-
-
20244375856
-
The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: Implications for molecular-based chemoprevention
-
Kong G, Kim HT, Wu K, et al. The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer Res 2005;65: 3462-9.
-
(2005)
Cancer Res
, vol.65
, pp. 3462-3469
-
-
Kong, G.1
Kim, H.T.2
Wu, K.3
-
33
-
-
0242636844
-
Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: Effects on the insulin-like growth factor signaling pathway
-
Lassarre C, Ricort JM. Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: effects on the insulin-like growth factor signaling pathway. Endocrinology 2003;144:4811-9.
-
(2003)
Endocrinology
, vol.144
, pp. 4811-4819
-
-
Lassarre, C.1
Ricort, J.M.2
-
34
-
-
0026004501
-
Phosphorylation of c-jun mediated by MAP kinases
-
Pulverer BJ, Kyriakis JM, Avruch J, Nikolakaki E, Woodgett JR. Phosphorylation of c-jun mediated by MAP kinases. Nature 1991;353:670-4.
-
(1991)
Nature
, vol.353
, pp. 670-674
-
-
Pulverer, B.J.1
Kyriakis, J.M.2
Avruch, J.3
Nikolakaki, E.4
Woodgett, J.R.5
-
35
-
-
0027410854
-
Suppression of oncogene-induced transformation by a deletion mutant of c-jun
-
Brown PH, Alani R, Preis LH, Szabo E, Birrer MJ. Suppression of oncogene-induced transformation by a deletion mutant of c-jun. Oncogene 1993;8:877-86.
-
(1993)
Oncogene
, vol.8
, pp. 877-886
-
-
Brown, P.H.1
Alani, R.2
Preis, L.H.3
Szabo, E.4
Birrer, M.J.5
-
36
-
-
2342450078
-
2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line
-
2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line. Int J Cancer 2004;109: 867-74.
-
(2004)
Int J Cancer
, vol.109
, pp. 867-874
-
-
Sugioka, Y.1
Watanabe, T.2
Inagaki, Y.3
-
37
-
-
0028222136
-
A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum
-
Frost JA, Geppert TD, Cobb MH, Feramisco JR. A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc Natl Acad Sci U S A 1994;91:3844-8.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3844-3848
-
-
Frost, J.A.1
Geppert, T.D.2
Cobb, M.H.3
Feramisco, J.R.4
-
38
-
-
0028641601
-
Association of insulin receptor substrate-1 with integrins
-
Vuori K, Ruoslahti E. Association of insulin receptor substrate-1 with integrins. Science 1994;266:1576-8.
-
(1994)
Science
, vol.266
, pp. 1576-1578
-
-
Vuori, K.1
Ruoslahti, E.2
-
39
-
-
0035945638
-
Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells
-
Reiss K, Wang JY, Romano G, Tu X, Peruzzi F, Baserga R. Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells. Oncogene 2001;20:490-500.
-
(2001)
Oncogene
, vol.20
, pp. 490-500
-
-
Reiss, K.1
Wang, J.Y.2
Romano, G.3
Tu, X.4
Peruzzi, F.5
Baserga, R.6
-
40
-
-
0034951677
-
4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
-
4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion. Mol Cell Biol 2001;21:5082-93.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5082-5093
-
-
Shaw, L.M.1
-
41
-
-
0033610807
-
Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)
-
Lebrun P, Mothe-Satney I, Delahaye L, Van Obberghen E, Baron V. Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src). J Biol Chem 1998;273: 32244-53.
-
(1998)
J Biol Chem
, vol.273
, pp. 32244-32253
-
-
Lebrun, P.1
Mothe-Satney, I.2
Delahaye, L.3
Van Obberghen, E.4
Baron, V.5
-
42
-
-
0028839154
-
Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation
-
Surmacz E, Burgaud JL. Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. Clin Cancer Res 1995;1: 1429-36.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1429-1436
-
-
Surmacz, E.1
Burgaud, J.L.2
-
43
-
-
0035504405
-
Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
-
Jackson JG, Zhang X, Yoneda T, Yee D. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines. Oncogene 2001;20:7318-25.
-
(2001)
Oncogene
, vol.20
, pp. 7318-7325
-
-
Jackson, J.G.1
Zhang, X.2
Yoneda, T.3
Yee, D.4
-
44
-
-
0742304062
-
Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression
-
Zhang X, Kamaraju S, Hakuno F, et al. Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression. Breast Cancer Res Treat 2004;83:161-70.
-
(2004)
Breast Cancer Res Treat
, vol.83
, pp. 161-170
-
-
Zhang, X.1
Kamaraju, S.2
Hakuno, F.3
-
45
-
-
0035957414
-
Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes
-
Zhang J, Ou J, Bashmakov Y, Horton JD, Brown MS, Goldstein JL. Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes. Proc Natl Acad Sci U S A 2001;98:3756-61.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3756-3761
-
-
Zhang, J.1
Ou, J.2
Bashmakov, Y.3
Horton, J.D.4
Brown, M.S.5
Goldstein, J.L.6
-
46
-
-
0036777291
-
Mitogenic properties of insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture
-
Strange KS, Wilkinson D, Emerman JT. Mitogenic properties of insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture. Breast Cancer Res Treat 2002; 75:203-12.
-
(2002)
Breast Cancer Res Treat
, vol.75
, pp. 203-212
-
-
Strange, K.S.1
Wilkinson, D.2
Emerman, J.T.3
-
47
-
-
0032477854
-
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
-
Cheng M, Sexl V, Sherr CJ, Roussel MF. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc Natl Acad Sci U S A 1998;95:1091-6.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1091-1096
-
-
Cheng, M.1
Sexl, V.2
Sherr, C.J.3
Roussel, M.F.4
-
48
-
-
2342618936
-
Multiple roles of the PI3K/ PKB (Akt) pathway in cell cycle progression
-
Liang J, Slingerland JM. Multiple roles of the PI3K/ PKB (Akt) pathway in cell cycle progression. Cell Cycle 2003;2:339-45.
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
49
-
-
0036896612
-
Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes
-
Hallak H, Moehren G, Tang J, et al. Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes. Hepatology 2002; 36:1509-18.
-
(2002)
Hepatology
, vol.36
, pp. 1509-1518
-
-
Hallak, H.1
Moehren, G.2
Tang, J.3
-
50
-
-
0030000351
-
Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor
-
Burgaud JL, Baserga R. Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor. Exp Cell Res 1996; 223:412-9.
-
(1996)
Exp Cell Res
, vol.223
, pp. 412-419
-
-
Burgaud, J.L.1
Baserga, R.2
-
51
-
-
0345826131
-
The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase
-
Ahmad T, Farnie G, Hundred NJ, Anderson NG. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 2004;279:1713-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 1713-1719
-
-
Ahmad, T.1
Farnie, G.2
Hundred, N.J.3
Anderson, N.G.4
-
52
-
-
0037008761
-
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor
-
Gilmore AP, Valentijn AJ, Wang P, et al. Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor. J Biol Chem 2002;277:27643-50.
-
(2002)
J Biol Chem
, vol.277
, pp. 27643-27650
-
-
Gilmore, A.P.1
Valentijn, A.J.2
Wang, P.3
-
53
-
-
0033617446
-
Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways
-
Valentinis B, Romano G, Peruzzi F, et al. Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways. J Biol Chem 1999;274:12423-30.
-
(1999)
J Biol Chem
, vol.274
, pp. 12423-12430
-
-
Valentinis, B.1
Romano, G.2
Peruzzi, F.3
-
54
-
-
0030795150
-
Differential roles of IRS-1 and SHC signaling pathways in breast cancer cells
-
Nolan MK, Jankowska L, Prisco M, Xu S, Guvakova MA, Surmacz E. Differential roles of IRS-1 and SHC signaling pathways in breast cancer cells. Int J Cancer 1997;72:828-34.
-
(1997)
Int J Cancer
, vol.72
, pp. 828-834
-
-
Nolan, M.K.1
Jankowska, L.2
Prisco, M.3
Xu, S.4
Ma, G.5
Surmacz, E.6
-
55
-
-
1642446014
-
Regulatory nodes that integrate and coordinate signaling as potential targets for breast cancer therapy
-
Cui X, Lee AV. Regulatory nodes that integrate and coordinate signaling as potential targets for breast cancer therapy. Clin Cancer Res 2004;10:396-401S.
-
(2004)
Clin Cancer Res
, vol.10
-
-
Cui, X.1
Lee, A.V.2
-
56
-
-
7644237126
-
Involvement of insulin receptor substrate 2 in mammary tumor metastasis
-
Nagle JA, Ma Z, Byrne MA, White MF, Shaw LM. Involvement of insulin receptor substrate 2 in mammary tumor metastasis. Mol Cell Biol 2004;24:9726-35.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9726-9735
-
-
Nagle, J.A.1
Ma, Z.2
Byrne, M.A.3
White, M.F.4
Shaw, L.M.5
-
57
-
-
0034463086
-
Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains
-
Razzini G, Ingrosso A, Brancaccio A, Sciacchitano S, Esposito DL, Falasca M. Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains. Mol Endocrinol 2000;14:823-36.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 823-836
-
-
Razzini, G.1
Ingrosso, A.2
Brancaccio, A.3
Sciacchitano, S.4
Esposito, D.L.5
Falasca, M.6
-
58
-
-
11144234519
-
The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization
-
Hogan A, Yakubchyk Y, Chabot J, et al. The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization. J Biol Chem 2004;279: 53717-24.
-
(2004)
J Biol Chem
, vol.279
, pp. 53717-53724
-
-
Hogan, A.1
Yakubchyk, Y.2
Chabot, J.3
-
59
-
-
14644426519
-
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
-
Taniguchi CM, Ueki K, Kahn R. Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism. J Clin Invest 2005;115:718-27.
-
(2005)
J Clin Invest
, vol.115
, pp. 718-727
-
-
Taniguchi, C.M.1
Ueki, K.2
Kahn, R.3
-
60
-
-
17044448378
-
Mechanisms in LPA-induced tumor cell migration: Critical role of phosphorylated ERK
-
Stahle M, Veit C, Bachfischer U, et al. Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J Cell Sci 2003;116:3835-46.
-
(2003)
J Cell Sci
, vol.116
, pp. 3835-3846
-
-
Stahle, M.1
Veit, C.2
Bachfischer, U.3
-
61
-
-
0035476836
-
Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
-
Hauck CR, Sieg DJ, Hsia DA, et al. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 2001;61:7079-90.
-
(2001)
Cancer Res
, vol.61
, pp. 7079-7090
-
-
Hauck, C.R.1
Sieg, D.J.2
Hsia, D.A.3
-
62
-
-
1842482424
-
Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC δ signal transduction
-
Woo JH, Lim JH, Kim YH, et al. Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC δ signal transduction. Oncogene 2004;23:1845-53.
-
(2004)
Oncogene
, vol.23
, pp. 1845-1853
-
-
Woo, J.H.1
Lim, J.H.2
Kim, Y.H.3
-
63
-
-
0034688957
-
Biological and clinical associations of c-jun activation in human breast cancer
-
Gee JM, Barroso AF, Ellis IO, Robertson JF, Nicholson RI. Biological and clinical associations of c-jun activation in human breast cancer. Int J Cancer 2000;89:177-86.
-
(2000)
Int J Cancer
, vol.89
, pp. 177-186
-
-
Gee, J.M.1
Barroso, A.F.2
Ellis, I.O.3
Robertson, J.F.4
Nicholson, R.I.5
-
64
-
-
0034614098
-
Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo
-
Schiff R, Reddy P, Ahotupa M, et al. Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst 2000;92:1926-34.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1926-1934
-
-
Schiff, R.1
Reddy, P.2
Ahotupa, M.3
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