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Volumn 66, Issue 10, 2006, Pages 5304-5313

Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH2-terminal kinase/activator protein-1 signaling to regulate cell migration

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE 9; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; PROTEIN TYROSINE KINASE INHIBITOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

EID: 33744927684     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2858     Document Type: Article
Times cited : (66)

References (64)
  • 1
    • 0031616132 scopus 로고    scopus 로고
    • The IRS-signaling system: A network of docking proteins that mediate insulin and cytokine action
    • White MF. The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action. Recent Prog Horm Res 1998;53:119-38.
    • (1998) Recent Prog Horm Res , vol.53 , pp. 119-138
    • White, M.F.1
  • 2
    • 0028032894 scopus 로고
    • Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
    • Tamemoto H, Kadowaki T, Tobe K, et al. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 1994;372:182-6.
    • (1994) Nature , vol.372 , pp. 182-186
    • Tamemoto, H.1    Kadowaki, T.2    Tobe, K.3
  • 3
    • 0028032895 scopus 로고
    • Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
    • Araki E, Lipes MA, Patti ME, et al. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene. Nature 1994;372:186-90.
    • (1994) Nature , vol.372 , pp. 186-190
    • Araki, E.1    Lipes, M.A.2    Patti, M.E.3
  • 4
    • 0032567937 scopus 로고    scopus 로고
    • Disruption of IRS-2 causes type 2 diabetes in mice
    • Withers DJ, Gutierrez JS, Towery H, et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 1998;391: 900-4.
    • (1998) Nature , vol.391 , pp. 900-904
    • Withers, D.J.1    Gutierrez, J.S.2    Towery, H.3
  • 5
    • 0040973209 scopus 로고    scopus 로고
    • Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells
    • Bruning JC, Winnay J, Cheatham B, Kahn CR. Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells. Mol Cell Biol 1997;17:1513-21.
    • (1997) Mol Cell Biol , vol.17 , pp. 1513-1521
    • Bruning, J.C.1    Winnay, J.2    Cheatham, B.3    Kahn, C.R.4
  • 6
    • 0028124504 scopus 로고
    • Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation
    • Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation. Mol Cell Biol 1994;14:6674-82.
    • (1994) Mol Cell Biol , vol.14 , pp. 6674-6682
    • Noguchi, T.1    Matozaki, T.2    Horita, K.3    Fujioka, Y.4    Kasuga, M.5
  • 7
    • 0033515459 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway
    • Li J, DeFea K, Roth RA. Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway. J Biol Chem 1999;274: 9351-6.
    • (1999) J Biol Chem , vol.274 , pp. 9351-9356
    • Li, J.1    DeFea, K.2    Roth, R.A.3
  • 9
    • 0031465447 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
    • De Fea K, Roth RA. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J Biol Chem 1997;272: 31400-6.
    • (1997) J Biol Chem , vol.272 , pp. 31400-31406
    • De Fea, K.1    Roth, R.A.2
  • 10
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000;275:9047-54.
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 11
    • 1542616960 scopus 로고    scopus 로고
    • Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation
    • Carlson CJ, White MF, Rondinone CM. Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation. Biochem Biophys Res Commun 2004;316: 533-9.
    • (2004) Biochem Biophys Res Commun , vol.316 , pp. 533-539
    • Carlson, C.J.1    White, M.F.2    Rondinone, C.M.3
  • 12
    • 0028018858 scopus 로고
    • The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin
    • Lam K, Carpenter CL, Ruderman NB, Friel JC, Kelly KL. The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin. J Biol Chem 1994;269: 20648-52.
    • (1994) J Biol Chem , vol.269 , pp. 20648-20652
    • Lam, K.1    Carpenter, C.L.2    Ruderman, N.B.3    Friel, J.C.4    Kelly, K.L.5
  • 13
    • 0035793592 scopus 로고    scopus 로고
    • Protein kinase C-ζ phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin
    • Ravichandran LV Esposito DL, Chen J, Quon MJ. Protein kinase C-ζ phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. J Biol Chem 2001;276:3543-9.
    • (2001) J Biol Chem , vol.276 , pp. 3543-3549
    • Ravichandran, L.V.1    Esposito, D.L.2    Chen, J.3    Quon, M.J.4
  • 14
    • 0037155132 scopus 로고    scopus 로고
    • Active Rho kinase (ROK-α) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells
    • Begum N, Sandu OA, Ito M, Lohmann SM, Smolenski A. Active Rho kinase (ROK-α) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J Biol Chem 2002;277: 6214-22.
    • (2002) J Biol Chem , vol.277 , pp. 6214-6222
    • Begum, N.1    Sandu, O.A.2    Ito, M.3    Lohmann, S.M.4    Smolenski, A.5
  • 15
    • 0033214461 scopus 로고    scopus 로고
    • Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function
    • Paz K, Liu YF, Shorer H, et al. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. J Biol Chem 1999; 274:28816-22.
    • (1999) J Biol Chem , vol.274 , pp. 28816-28822
    • Paz, K.1    Liu, Y.F.2    Shorer, H.3
  • 16
    • 13844272212 scopus 로고    scopus 로고
    • Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation
    • Kaiser C, James SR. Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation. BMC Biol 2004;2:23.
    • (2004) BMC Biol , vol.2 , pp. 23
    • Kaiser, C.1    James, S.R.2
  • 17
    • 0033982719 scopus 로고    scopus 로고
    • Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3′-kinase inhibition
    • Lee AV, Gooch JL, Oesterreich S, Guler RL, Yee D. Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3′-kinase inhibition. Mol Cell Biol 2000;20:1489-96.
    • (2000) Mol Cell Biol , vol.20 , pp. 1489-1496
    • Lee, A.V.1    Gooch, J.L.2    Oesterreich, S.3    Guler, R.L.4    Yee, D.5
  • 18
    • 0000085132 scopus 로고    scopus 로고
    • Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway
    • Sun XJ, Goldberg JL, Qiao LY, Mitchell JJ. Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway. Diabetes 1999;48:1359-64.
    • (1999) Diabetes , vol.48 , pp. 1359-1364
    • Sun, X.J.1    Goldberg, J.L.2    Qiao, L.Y.3    Mitchell, J.J.4
  • 20
    • 0027421453 scopus 로고
    • The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro
    • Smith LK, Bradshaw M, Croall DE, Garner CW. The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro. Biochem Biophys Res Commun 1993;196:767-72.
    • (1993) Biochem Biophys Res Commun , vol.196 , pp. 767-772
    • Smith, L.K.1    Bradshaw, M.2    Croall, D.E.3    Garner, C.W.4
  • 21
    • 0242574322 scopus 로고    scopus 로고
    • Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2
    • Cui X, Lazard Z, Zhang P, Hopp TA, Lee AV. Progesterone crosstalks with insulin-like growth factor signaling in breast cancer cells via induction of insulin receptor substrate-2. Oncogene 2003;22:6937-41.
    • (2003) Oncogene , vol.22 , pp. 6937-6941
    • Cui, X.1    Lazard, Z.2    Zhang, P.3    Hopp, T.A.4    Lee, A.V.5
  • 22
    • 0033305004 scopus 로고    scopus 로고
    • Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
    • Lee AV, Jackson JG, Gooch JL, et al. Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 1999;13:787-96.
    • (1999) Mol Endocrinol , vol.13 , pp. 787-796
    • Lee, A.V.1    Jackson, J.G.2    Gooch, J.L.3
  • 23
    • 0034967344 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: New insights into their synergistic effects
    • Dupont J, Le Roith D. Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects. Mol Pathol 2001;54:149-54.
    • (2001) Mol Pathol , vol.54 , pp. 149-154
    • Dupont, J.1    Le Roith, D.2
  • 24
    • 0034624106 scopus 로고    scopus 로고
    • Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression
    • Lebrun P, Baron V, Hauck CR, Schlaepfer DD, Van Obberghen E. Cell adhesion and focal adhesion kinase regulate insulin receptor substrate-1 expression. J Biol Chem 2000;275:38371-7.
    • (2000) J Biol Chem , vol.275 , pp. 38371-38377
    • Lebrun, P.1    Baron, V.2    Hauck, C.R.3    Schlaepfer, D.D.4    Van Obberghen, E.5
  • 25
    • 0029029137 scopus 로고
    • Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells
    • Ram TG, Kokeny KE, Dilts CA, Ethier SP. Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells. J Cell Physiol 1995;163:589-96.
    • (1995) J Cell Physiol , vol.163 , pp. 589-596
    • Ram, T.G.1    Kokeny, K.E.2    Dilts, C.A.3    Ethier, S.P.4
  • 26
    • 0036231180 scopus 로고    scopus 로고
    • Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells
    • Stull MA, Richert MM, Loladze AV, Wood TL. Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells. Endocrinology 2002;143:1872-9.
    • (2002) Endocrinology , vol.143 , pp. 1872-1879
    • Stull, M.A.1    Richert, M.M.2    Loladze, A.V.3    Wood, T.L.4
  • 28
    • 0034698105 scopus 로고    scopus 로고
    • Insulin-like growth factor I-mediated degradation of insulin receptor substrate-I is inhibited by epidermal growth factor in prostate epithelial cells
    • Zhang H, Hoff H, Sell C. Insulin-like growth factor I-mediated degradation of insulin receptor substrate-I is inhibited by epidermal growth factor in prostate epithelial cells. J Biol Chem 2000;275:22558-62.
    • (2000) J Biol Chem , vol.275 , pp. 22558-22562
    • Zhang, H.1    Hoff, H.2    Sell, C.3
  • 29
    • 0037385522 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: Progesterone receptor as a potential indicator of growth factor activity in breast cancer
    • Cui X, Zhang P, Deng W, et al. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer. Mol Endocrinol 2003;17: 575-88.
    • (2003) Mol Endocrinol , vol.17 , pp. 575-588
    • Cui, X.1    Zhang, P.2    Deng, W.3
  • 30
    • 0037119423 scopus 로고    scopus 로고
    • Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype
    • Rennefahrt UE, Illert B, Kerkhoff E, Troppmair J, Rapp UR. Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype. J Biol Chem 2002;277:29510-8.
    • (2002) J Biol Chem , vol.277 , pp. 29510-29518
    • Rennefahrt, U.E.1    Illert, B.2    Kerkhoff, E.3    Troppmair, J.4    Rapp, U.R.5
  • 31
    • 0030802419 scopus 로고    scopus 로고
    • A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis
    • Olive M, Krylov D, Echlin DR, Gardner K, Taparowsky E, Vinson C. A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis. J Biol Chem 1997;272:18586-94.
    • (1997) J Biol Chem , vol.272 , pp. 18586-18594
    • Olive, M.1    Krylov, D.2    Echlin, D.R.3    Gardner, K.4    Taparowsky, E.5    Vinson, C.6
  • 32
    • 20244375856 scopus 로고    scopus 로고
    • The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: Implications for molecular-based chemoprevention
    • Kong G, Kim HT, Wu K, et al. The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer Res 2005;65: 3462-9.
    • (2005) Cancer Res , vol.65 , pp. 3462-3469
    • Kong, G.1    Kim, H.T.2    Wu, K.3
  • 33
    • 0242636844 scopus 로고    scopus 로고
    • Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: Effects on the insulin-like growth factor signaling pathway
    • Lassarre C, Ricort JM. Growth factor-specific regulation of insulin receptor substrate-1 expression in MCF-7 breast carcinoma cells: effects on the insulin-like growth factor signaling pathway. Endocrinology 2003;144:4811-9.
    • (2003) Endocrinology , vol.144 , pp. 4811-4819
    • Lassarre, C.1    Ricort, J.M.2
  • 35
    • 0027410854 scopus 로고
    • Suppression of oncogene-induced transformation by a deletion mutant of c-jun
    • Brown PH, Alani R, Preis LH, Szabo E, Birrer MJ. Suppression of oncogene-induced transformation by a deletion mutant of c-jun. Oncogene 1993;8:877-86.
    • (1993) Oncogene , vol.8 , pp. 877-886
    • Brown, P.H.1    Alani, R.2    Preis, L.H.3    Szabo, E.4    Birrer, M.J.5
  • 36
    • 2342450078 scopus 로고    scopus 로고
    • 2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line
    • 2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line. Int J Cancer 2004;109: 867-74.
    • (2004) Int J Cancer , vol.109 , pp. 867-874
    • Sugioka, Y.1    Watanabe, T.2    Inagaki, Y.3
  • 37
    • 0028222136 scopus 로고
    • A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum
    • Frost JA, Geppert TD, Cobb MH, Feramisco JR. A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc Natl Acad Sci U S A 1994;91:3844-8.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3844-3848
    • Frost, J.A.1    Geppert, T.D.2    Cobb, M.H.3    Feramisco, J.R.4
  • 38
    • 0028641601 scopus 로고
    • Association of insulin receptor substrate-1 with integrins
    • Vuori K, Ruoslahti E. Association of insulin receptor substrate-1 with integrins. Science 1994;266:1576-8.
    • (1994) Science , vol.266 , pp. 1576-1578
    • Vuori, K.1    Ruoslahti, E.2
  • 39
    • 0035945638 scopus 로고    scopus 로고
    • Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells
    • Reiss K, Wang JY, Romano G, Tu X, Peruzzi F, Baserga R. Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells. Oncogene 2001;20:490-500.
    • (2001) Oncogene , vol.20 , pp. 490-500
    • Reiss, K.1    Wang, J.Y.2    Romano, G.3    Tu, X.4    Peruzzi, F.5    Baserga, R.6
  • 40
    • 0034951677 scopus 로고    scopus 로고
    • 4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
    • 4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion. Mol Cell Biol 2001;21:5082-93.
    • (2001) Mol Cell Biol , vol.21 , pp. 5082-5093
    • Shaw, L.M.1
  • 41
    • 0033610807 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)
    • Lebrun P, Mothe-Satney I, Delahaye L, Van Obberghen E, Baron V. Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src). J Biol Chem 1998;273: 32244-53.
    • (1998) J Biol Chem , vol.273 , pp. 32244-32253
    • Lebrun, P.1    Mothe-Satney, I.2    Delahaye, L.3    Van Obberghen, E.4    Baron, V.5
  • 42
    • 0028839154 scopus 로고
    • Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation
    • Surmacz E, Burgaud JL. Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. Clin Cancer Res 1995;1: 1429-36.
    • (1995) Clin Cancer Res , vol.1 , pp. 1429-1436
    • Surmacz, E.1    Burgaud, J.L.2
  • 43
    • 0035504405 scopus 로고    scopus 로고
    • Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
    • Jackson JG, Zhang X, Yoneda T, Yee D. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines. Oncogene 2001;20:7318-25.
    • (2001) Oncogene , vol.20 , pp. 7318-7325
    • Jackson, J.G.1    Zhang, X.2    Yoneda, T.3    Yee, D.4
  • 44
    • 0742304062 scopus 로고    scopus 로고
    • Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression
    • Zhang X, Kamaraju S, Hakuno F, et al. Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression. Breast Cancer Res Treat 2004;83:161-70.
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 161-170
    • Zhang, X.1    Kamaraju, S.2    Hakuno, F.3
  • 45
    • 0035957414 scopus 로고    scopus 로고
    • Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes
    • Zhang J, Ou J, Bashmakov Y, Horton JD, Brown MS, Goldstein JL. Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes. Proc Natl Acad Sci U S A 2001;98:3756-61.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 3756-3761
    • Zhang, J.1    Ou, J.2    Bashmakov, Y.3    Horton, J.D.4    Brown, M.S.5    Goldstein, J.L.6
  • 46
    • 0036777291 scopus 로고    scopus 로고
    • Mitogenic properties of insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture
    • Strange KS, Wilkinson D, Emerman JT. Mitogenic properties of insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture. Breast Cancer Res Treat 2002; 75:203-12.
    • (2002) Breast Cancer Res Treat , vol.75 , pp. 203-212
    • Strange, K.S.1    Wilkinson, D.2    Emerman, J.T.3
  • 47
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • Cheng M, Sexl V, Sherr CJ, Roussel MF. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc Natl Acad Sci U S A 1998;95:1091-6.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 48
    • 2342618936 scopus 로고    scopus 로고
    • Multiple roles of the PI3K/ PKB (Akt) pathway in cell cycle progression
    • Liang J, Slingerland JM. Multiple roles of the PI3K/ PKB (Akt) pathway in cell cycle progression. Cell Cycle 2003;2:339-45.
    • (2003) Cell Cycle , vol.2 , pp. 339-345
    • Liang, J.1    Slingerland, J.M.2
  • 49
    • 0036896612 scopus 로고    scopus 로고
    • Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes
    • Hallak H, Moehren G, Tang J, et al. Epidermal growth factor-induced activation of the insulin-like growth factor I receptor in rat hepatocytes. Hepatology 2002; 36:1509-18.
    • (2002) Hepatology , vol.36 , pp. 1509-1518
    • Hallak, H.1    Moehren, G.2    Tang, J.3
  • 50
    • 0030000351 scopus 로고    scopus 로고
    • Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor
    • Burgaud JL, Baserga R. Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor. Exp Cell Res 1996; 223:412-9.
    • (1996) Exp Cell Res , vol.223 , pp. 412-419
    • Burgaud, J.L.1    Baserga, R.2
  • 51
    • 0345826131 scopus 로고    scopus 로고
    • The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase
    • Ahmad T, Farnie G, Hundred NJ, Anderson NG. The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 2004;279:1713-9.
    • (2004) J Biol Chem , vol.279 , pp. 1713-1719
    • Ahmad, T.1    Farnie, G.2    Hundred, N.J.3    Anderson, N.G.4
  • 52
    • 0037008761 scopus 로고    scopus 로고
    • Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor
    • Gilmore AP, Valentijn AJ, Wang P, et al. Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor. J Biol Chem 2002;277:27643-50.
    • (2002) J Biol Chem , vol.277 , pp. 27643-27650
    • Gilmore, A.P.1    Valentijn, A.J.2    Wang, P.3
  • 53
    • 0033617446 scopus 로고    scopus 로고
    • Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways
    • Valentinis B, Romano G, Peruzzi F, et al. Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways. J Biol Chem 1999;274:12423-30.
    • (1999) J Biol Chem , vol.274 , pp. 12423-12430
    • Valentinis, B.1    Romano, G.2    Peruzzi, F.3
  • 54
    • 0030795150 scopus 로고    scopus 로고
    • Differential roles of IRS-1 and SHC signaling pathways in breast cancer cells
    • Nolan MK, Jankowska L, Prisco M, Xu S, Guvakova MA, Surmacz E. Differential roles of IRS-1 and SHC signaling pathways in breast cancer cells. Int J Cancer 1997;72:828-34.
    • (1997) Int J Cancer , vol.72 , pp. 828-834
    • Nolan, M.K.1    Jankowska, L.2    Prisco, M.3    Xu, S.4    Ma, G.5    Surmacz, E.6
  • 55
    • 1642446014 scopus 로고    scopus 로고
    • Regulatory nodes that integrate and coordinate signaling as potential targets for breast cancer therapy
    • Cui X, Lee AV. Regulatory nodes that integrate and coordinate signaling as potential targets for breast cancer therapy. Clin Cancer Res 2004;10:396-401S.
    • (2004) Clin Cancer Res , vol.10
    • Cui, X.1    Lee, A.V.2
  • 56
    • 7644237126 scopus 로고    scopus 로고
    • Involvement of insulin receptor substrate 2 in mammary tumor metastasis
    • Nagle JA, Ma Z, Byrne MA, White MF, Shaw LM. Involvement of insulin receptor substrate 2 in mammary tumor metastasis. Mol Cell Biol 2004;24:9726-35.
    • (2004) Mol Cell Biol , vol.24 , pp. 9726-9735
    • Nagle, J.A.1    Ma, Z.2    Byrne, M.A.3    White, M.F.4    Shaw, L.M.5
  • 57
    • 0034463086 scopus 로고    scopus 로고
    • Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains
    • Razzini G, Ingrosso A, Brancaccio A, Sciacchitano S, Esposito DL, Falasca M. Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains. Mol Endocrinol 2000;14:823-36.
    • (2000) Mol Endocrinol , vol.14 , pp. 823-836
    • Razzini, G.1    Ingrosso, A.2    Brancaccio, A.3    Sciacchitano, S.4    Esposito, D.L.5    Falasca, M.6
  • 58
    • 11144234519 scopus 로고    scopus 로고
    • The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization
    • Hogan A, Yakubchyk Y, Chabot J, et al. The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization. J Biol Chem 2004;279: 53717-24.
    • (2004) J Biol Chem , vol.279 , pp. 53717-53724
    • Hogan, A.1    Yakubchyk, Y.2    Chabot, J.3
  • 59
    • 14644426519 scopus 로고    scopus 로고
    • Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
    • Taniguchi CM, Ueki K, Kahn R. Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism. J Clin Invest 2005;115:718-27.
    • (2005) J Clin Invest , vol.115 , pp. 718-727
    • Taniguchi, C.M.1    Ueki, K.2    Kahn, R.3
  • 60
    • 17044448378 scopus 로고    scopus 로고
    • Mechanisms in LPA-induced tumor cell migration: Critical role of phosphorylated ERK
    • Stahle M, Veit C, Bachfischer U, et al. Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J Cell Sci 2003;116:3835-46.
    • (2003) J Cell Sci , vol.116 , pp. 3835-3846
    • Stahle, M.1    Veit, C.2    Bachfischer, U.3
  • 61
    • 0035476836 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
    • Hauck CR, Sieg DJ, Hsia DA, et al. Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells. Cancer Res 2001;61:7079-90.
    • (2001) Cancer Res , vol.61 , pp. 7079-7090
    • Hauck, C.R.1    Sieg, D.J.2    Hsia, D.A.3
  • 62
    • 1842482424 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC δ signal transduction
    • Woo JH, Lim JH, Kim YH, et al. Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC δ signal transduction. Oncogene 2004;23:1845-53.
    • (2004) Oncogene , vol.23 , pp. 1845-1853
    • Woo, J.H.1    Lim, J.H.2    Kim, Y.H.3
  • 64
    • 0034614098 scopus 로고    scopus 로고
    • Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo
    • Schiff R, Reddy P, Ahotupa M, et al. Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst 2000;92:1926-34.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1926-1934
    • Schiff, R.1    Reddy, P.2    Ahotupa, M.3


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