CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake

Journal of Molecular and Cellular Cardiology

Volumn 40, Issue 6, 2006, Pages 783-789

  Kadono, Toshie ^a   Zhang, Xiu Quan ^a   Srinivasan, Sathya ^a   Ishida, Hideyuki ^b   Barry, William H ^a   Benjamin, Ivor J ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Calcium; Heat shock proteins; Metabolic inhibition; Mitochondria

Indexed keywords

ARSENOSOBENZENE; CALCIUM ION; CRYAB PROTEIN; CYCLOSPORIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN B2; NITRIC OXIDE; OUABAIN; TETRAMETHYLRHODAMINE METHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; FLUORESCENCE; HEART MUSCLE ISCHEMIA; HEART VENTRICLE; KNOCKOUT MOUSE; MEMBRANE PERMEABILITY; METABOLIC INHIBITION; MITOCHONDRIAL MEMBRANE; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REPERFUSION INJURY; WILD TYPE;

ALPHA-CRYSTALLIN B CHAIN; ANIMALS; ARSENICALS; CALCIUM; CALCIUM SIGNALING; HEAT-SHOCK PROTEINS; INTRACELLULAR MEMBRANES; MICE; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; NITRIC OXIDE; OUABAIN; PERMEABILITY; RHODAMINES; TIME FACTORS;

STROPHANTHUS GRATUS;

EID: 33744541387     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2006.03.003     Document Type: Article

References (33)

1. Taylor R.P., and Benjamin I.J. Small heat shock proteins: a new classification scheme in mammals. J. Mol. Cell. Cardiol. 38 (2005) 433-444
2. Golenhofen N., Ness W., Koob R., Htun P., Schaper W., and Drenckhahn D. Ischemia-induced phosphorylation and translocation of stress protein alpha B-crystallin to Z lines of myocardium. Am. J. Physiol. 274 (1998) H1457-H1464
3. Kamradt M.C., Lu M., Werner M.E., Kwan T., Chen F., Strohecker A., et al. The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3. J. Biol. Chem. 280 (2005) 11059-11066
4. Morrison L.E., Hoover H.E., Thuerauf D.J., and Glembotski C.C. Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ. Res. 92 (2003) 203-211
5. Paulin D., Huet A., Khanamyrian L., and Xue Z. Desminopathies in muscle disease. J. Pathol. 204 (2004) 418-427
6. Morrison L.E., Whittaker R.J., Klepper R.E., Wawrousek E.F., and Glembotski C.C. Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model. Am. J. Physiol.: Heart Circ. Physiol. 286 (2004) H847-H855
7. Vicart P., Caron A., Guicheney P., Li Z., Prevost M.C., Faure A., et al. A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat. Genet. 20 (1998) 92-95
8. Suzuki A., Sugiyama Y., Hauashi Y., Nyu-I N., Yoshida M., Nonaka I., et al. MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase. J. Cell Biol. 140 (1998) 1113-1124
9. Iwaki A., Nagano T., Nakagawa M., Iwaki T., and Fukumaki Y. Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner. Genomics 45 2 (1997) 386-394
10. Brady J.P., Garland D.L., Green D.E., Tamm E.R., Giblin F.J., and Wawrousek E.F. AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach. Invest. Ophthalmol. Visual Sci. 42 (2001) 2924-2934
11. Nakagawa M., Tsujimoto N., Nakagawa H., Iwaki T., Fukumaki Y., and Iwaki A. Association of HSPB2, a member of the small heat shock protein family, with mitochondria. Exp. Cell Res. 271 (2001) 161-168
12. Barry W.H. Calcium and ischemic injury. Trends Cardiovasc. Med. 1 (1991) 162-166
13. 2+ exchanger. CIRC 104 (2001) 2101-2106
14. 2+ overload with accompanying depolarization of the mitochondrial membrane in the heart. Naunyn-Schmiedeberg's Arch. Pharmacol. 369 (2004) 192-197
15. 2+ release in cardiac myocytes: role of mitochondria. Cell Calcium 38 (2005) 1-9
16. Gursahani H.I., and Schaefer S. Acidification reduces mitochondrial calcium uptake in rat cardiac mitochondria. Am. J. Physiol.: Heart Circ. Physiol. 287 (2004) H2659-H2665
17. Dedkova E.N., Ji X., Lipsius S.L., and Blatter L.A. Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells. Am. J. Physiol.: Cell Physiol. 286 (2004) C406-C415
18. Hausenloy D.J., Yellon D.M., Mani-Babu S., and Duchen M.R. Preconditioning protects by inhibiting the mitochondrial permeability transition. Am. J. Physiol.: Heart Circ. Physiol. 287 (2004) H841-H849
19. 2+ and contracture in metabolically inhibited cardiomyocytes. J. Pharmacol. Exp. Ther. 285 (1998) 716-723
20. Rodriguez-Larrain J.M., Sharma P., Sugishita K., Nonaka A., Yauney K.D., and Barry W.H. Effects of endothelin 1 on cation concentrations and viability of ventricular myocytes during ATP depletion: assessment by flow cytometry. Analyt. Pharmacol. 2 1 (2001) 1-8
21. i in rabbit ventricular myocytes during metabolic inhibition. J. Mol. Cell. Cardiol. 3 (2001) 2145-2155
22. i during metabolic inhibition. J. Mol. Cell. Cardiol. 35 (2003) 331-336
23. Gunter T.E., Yule D.I., Gunter K.K., Eliseev R.A., and Salter J.D. Calcium and mitochondria. FEBS Lett. 567 (2004) 96-102
24. 2+ by nitric oxide in cultured bovine vascular endothelial cells". Am. J. Physiol.: Cell Physiol. 289 (2005) C775-C777
25. 2+ by nitric oxide in cultured bovine vascular endothelial cells. Am. J. Physiol.: Cell Physiol. 289 (2005) 836-845
26. Brookes P.S., Yoon Y., Robotham J.L., Anders M.N., and Sheu S.-S. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am. J. Physiol.: Cell Physiol. 287 (2004) C817-C833
27. Weiss J.N., Korge P., Honda H.M., and Ping P. Role of the mitochondrial permeability transition in myocardial disease. Circ. Res. 93 (2003) 292
28. Korge P., Goldhaber J.I., and Weiss J.N. Phenylarsine oxide induces mitochondrial permeability transition, hypercontracture, and cardiac cell death. Am. J. Physiol.: Heart Circ. Physiol. 280 (2001) H2203-H2213
29. 2+ overload and the mitochondrial permeability transition pore opening. CIRC 110 (2004) III-105 [Abstract]
30. He L., and Lemasters J.J. Heat shock suppresses the permeability transition in rat liver mitochondria. J. Biol. Chem. 278 (2003) 16755-16760
31. Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A., et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434 (2005) 658-662
32. Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434 (2005) 652-658
33. 2+-overloaded cultured rat cardiomyocytes. Am. J. Physiol.: Heart Circ. Physiol. 274 (1998) 2085-2093