Small heat shock proteins: A new classification scheme in mammals

Journal of Molecular and Cellular Cardiology

Volumn 38, Issue 3, 2005, Pages 433-444

  Taylor, Ryan P ^a   Benjamin, Ivor J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Cardioprotection; Chaperone; Crystallin; Ischemia; Myocardium

Indexed keywords

ALPHA B CRYSTALLIN; ALPHA CRYSTALLIN; CHAPERONE; CRYSTALLIN; HEAT SHOCK ASSOCIATED PROTEIN B 2; HEAT SHOCK ASSOCIATED PROTEIN B 3; HEAT SHOCK ASSOCIATED PROTEIN B 7; HEAT SHOCK ASSOCIATED PROTEIN B 8; HEAT SHOCK ASSOCIATED PROTEIN B 9; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 20; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 27; HEAT SHOCK TRANSCRIPTION FACTOR 1; OSTEOCLAST DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; CELL LINEAGE; CLASSIFICATION; CYTOKINE PRODUCTION; CYTOSKELETON; GENE EXPRESSION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; INHERITANCE; MOLECULAR SIZE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; SEQUENCE HOMOLOGY; SKELETAL MUSCLE;

EID: 14744291911     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.12.014     Document Type: Review

References (138)

1. F.M. Ritossa A new puffing pattern induced by a temperature shock and DNP in Drosophila Experientia 18 1962 571 573
2. M. Ashburner, and J.J. Bonner The induction of gene activity in drosophilia by heat shock Cell 17 1979 241 254
3. M. Haslbeck sHsps and their role in the chaperone network Cell. Mol. Life Sci. 59 2002 1649 1657
4. E. Ganea Chaperone-like activity of alpha-crystallin and other small heat shock proteins Curr. Protein Pept. Sci. 2 2001 205 225
5. N. Mounier, and A.P. Arrigo Actin cytoskeleton and small heat shock proteins: how do they interact? Cell Stress Chaperones 7 2002 167 176
6. F. Narberhaus Alpha-crystallin-type heat shock proteins: socializing minichaperones in the context of a multichaperone network Microbiol. Mol. Biol. Rev. 66 2002 64 93
7. R. Van Montfort, C. Slingsby, and E. Vierling Structure and function of the small heat shock protein/alpha-crystallin family of molecular chaperones Adv. Protein Chem. 59 2001 105 156
8. D.S. Latchman Heat shock proteins and cardiac protection Cardiovasc. Res. 51 2001 637 646
9. C.T. Mörner Untersuchung der Proteinsubstanzen in den lichtbrechenden Medien des Auges Hoppe Seylers Z. Physiol. Chem. 18 1894 61 106
10. S.G. Waley Structural studies of alpha-crystallin Biochem. J. 96 1965 722 728
11. S. Lerman The structural proteins of the ocular lens Surv. Ophthalmol. 12 1967 112 129
12. H. Bloemendal Lens proteins CRC Crit. Rev. Biochem. 12 1982 1 38
13. F. Ramaekers, H. Dodemont, P. Vorstenbosch, and H. Bloemendal Classification of rat lens crystallins and identification of proteins encoded by rat lens mRNA Eur. J. Biochem. 128 1982 503 508
14. T.D. Ingolia, and E.A. Craig Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin Proc. Natl. Acad. Sci. USA 79 1982 2360 2360
15. J. Piatigorsky Molecular biology: recent studies on enzyme/crystallins and alpha-crystallin gene expression Exp. Eye Res. 50 1990 725 728
16. J. Piatigorsky Crystallin genes: specialization by changes in gene regulation may precede gene duplication J. Struct. Funct. Genomics 3 2003 131 137
17. W. Hendriks, J.W. Mulders, M.A. Bibby, C. Slingsby, H. Bloemendal, and W.W. de Jong Duck lens epsilon-crystallin and lactate dehydrogenase B4 are identical: a single-copy gene product with two distinct functions Proc. Natl. Acad. Sci. USA 85 1988 7114 7118
18. G.A. Brunekreef, H.J. Kraft, J.G. Schoenmakers, and N.H. Lubsen The mechanism of recruitment of the lactate dehydrogenase-B/epsilon-crystallin gene by the duck lens J. Mol. Biol. 262 1996 629 639
19. R.A. Dubin, E.F. Wawrousek, and J. Piatigorsky Expression of the murine alpha B-crystallin gene is not restricted to the lens Mol. Cell. Biol. 9 1989 1083 1091
20. R.I. Morimoto Regulation of the heat shock transcriptional response: cross-talk between a family of heat shock factors, molecular chaperones, and negative regulators Genes Dev. 12 1998 3788 3796
21. E.S. Christians, L.J. Yan, and I.J. Benjamin Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury Crit. Care Med. 30 2002 S43 S50
22. D.R. McMillan, X. Xiao, L. Shao, K. Graves, and I.J. Benjamin Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis J. Biol. Chem. 273 1998 7523 7528
23. X. Xiao, X. Zuo, A.A. Davis, D.R. McMillan, B.B. Curry, and J.A. Richardson HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice EMBO J. 18 1999 5943 5952
24. L.J. Yan, E.S. Christians, L. Liu, X. Xiao, R.S. Sohal, and I.J. Benjamin Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage EMBO J. 21 2002 5164 5172
25. J. Zou, W.F. Salminen, S.M. Roberts, and R. Voellmy Correlation between glutathione oxidation and trimerization of heat shock factor 1, an early step in stress induction of the Hsp response Cell Stress Chaperones 3 1998 130 141
26. A.P. Arrigo Gene expression and the thiol redox state Free Radic. Biol. Med. 27 1999 936 944
27. M. Zhong, A. Orosz, and C. Wu Direct sensing of heat and oxidation by Drosophila heat shock transcription factor Mol. Cell 2 1998 101 108
28. D.J. Manalo, and A.Y. Liu Resolution, detection, and characterization of redox conformers of human HSF1 J. Biol. Chem. 276 2001 23554 25561
29. E.R. Stadtman Importance of individuality in oxidative stress and aging Free Radic. Biol. Med. 33 2002 597 604
30. S.G. Ahn, and D.J. Thiele Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress Genes Dev. 17 2003 516 528
31. R. Gopal-Srivastava, and J. Piatigorsky The murine alpha B-crystallin/small heat shock protein enhancer: identification of alpha BE-1, alpha BE-2, alpha BE-3, and MRF control elements Mol. Cell. Biol. 13 1993 7144 7152
32. R. Klemenz, E. Frohli, R.H. Steiger, R. Schafer, and A. Aoyama Alpha B-crystallin is a small heat shock protein Proc. Natl. Acad. Sci. USA 88 1991 3652 3656
33. P.D. Neufer, and I.J. Benjamin Differential expression of B-crystallin and Hsp27 in skeletal muscle during continuous contractile activity. Relationship to myogenic regulatory factors J. Biol. Chem. 271 1996 24089 24095
34. R. Gopal-Srivastava, J.I. Haynes 2nd, and J. Piatigorsky Regulation of the murine alpha B-crystallin/small heat shock protein gene in cardiac muscle Mol. Cell. Biol. 15 1995 7081 7090
35. A. Iwaki, T. Nagano, M. Nakagawa, T. Iwaki, and Y. Fukumaki Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner Genomics 45 1997 386 394
36. A. Suzuki, Y. Sugiyama, Y. Hayashi, N. Nyu-i, M. Yoshida, and I. Nonaka MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase J. Cell Biol. 140 1998 1113 1124
37. K. Yoshida, T. Aki, K. Harada, K.M. Shama, Y. Kamoda, and A. Suzuki Translocation of HSP27 and MKBP in ischemic heart Cell Struct. Funct. 24 1999 181 185
38. S.K. Swamynathan, and J. Piatigorsky Orientation-dependent influence of an intergenic enhancer on the promoter activity of the divergently transcribed mouse Shsp/alpha B-crystallin and Mkbp/HspB2 genes J. Biol. Chem. 277 2002 49700 49706
39. E.D. Hickey, and L.A. Weber Modulation of heat-shock polypeptide synthesis in HeLa cells during hyperthermia and recovery Biochemistry 21 1982 1513 1521
40. S. Michaud, G. Morrow, J. Marchand, and R.M. Tanguay Drosophila small heat shock proteins: cell and organelle-specific chaperones? Prog. Mol. Subcell. Biol. 28 2002 79 101
41. P. Laksanalamai, and F.T. Robb Small heat shock proteins from extremophiles: a review Extremophiles 8 2004 1 11
42. J. Horwitz Alpha-crystallin Exp. Eye Res. 76 2003 145 153
43. R.S. Williams, and I.J. Benjamin Stress proteins and cardiovascular disease Mol. Biol. Med. 8 1991 197 206
44. I.J. Benjamin, and D.R. McMillan Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease Circ. Res. 83 1998 117 132
45. J.L. Martin, R. Mestril, R. Hilal-Dandan, L.L. Brunton, and W.H. Dillmann Small heat shock proteins and protection against ischemic injury in cardiac myocytes Circulation 96 1997 4343 4348
46. J.W. Starnes Stress proteins and myocardial protection M. Locke E.G. Noble Exercise and stress response: the role of stress proteins 2002 CRC Press Boca Raton, FL 97 121
47. R.P. Taylor, and J.W. Starnes Age, cell signalling and cardioprotection Acta Physiol. Scand. 178 2003 107 116
48. W.H. Dillmann, and R. Mestril Heat shock proteins in myocardial stress Z. Kardiol. 84 Suppl 4 1995 87 90
49. W.H. Dillmann Heat shock proteins and protection against ischemic injury Infect. Dis. Obstet. Gynecol. 7 1999 55 57
50. W.H. Dillmann Small heat shock proteins and protection against injury Ann. N. Y. Acad. Sci. 874 1999 66 68
51. R. Mestril, and W.H. Dillmann Heat shock proteins and protection against myocardial ischemia J. Mol. Cell. Cardiol. 27 1995 45 52
52. U. Jakob, M. Gaestel, K. Engel, and J. Buchner Small heat shock proteins are molecular chaperones J. Biol. Chem. 268 1993 1517 1520
53. J. Horwitz Alpha-crystallin can function as a molecular chaperone Proc. Natl. Acad. Sci. USA 89 1992 10449 10453
54. L.G. Goldfarb, K.Y. Park, L. Cervenakova, S. Gorokhova, H.S. Lee, and O. Vasconcelos Missense mutations in desmin associated with familial cardiac and skeletal myopathy Nat. Genet. 19 1998 402 403
55. P. Vicart, A. Caron, P. Guicheney, Z. Li, M.C. Prevost, and A. Faure A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy Nat. Genet. 20 1998 92 95
56. A.T. Chavez Zobel, A. Loranger, N. Marceau, J.R. Theriault, H. Lambert, and J. Landry Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant Hum. Mol. Genet. 12 2003 1609 1620
57. X. Wang, R. Klevitsky, W. Huang, J. Glasford, F. Li, and J. Robbins AlphaB-crystallin modulates protein aggregation of abnormal desmin Circ. Res. 93 2003 998 1005
58. K. Megy, S. Audic, and J.M. Claverie Heart-specific genes revealed by expressed sequence tag (EST) sampling Genome Biol. 3 2002 research0074.1- research.11
59. S. Krief, J.F. Faivre, P. Robert, B. Le Douarin, N. Brument-Larignon, and I. Lefrere Identification and characterization of cvHsp. A novel human small stress protein selectively expressed in cardiovascular and insulin-sensitive tissues J. Biol. Chem. 274 1999 36592 36600
60. K. Okubo, N. Hori, R. Matoba, T. Niiyama, A. Fukushima, and Y. Kojima Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression Nat. Genet. 2 1992 173 179
61. A.E. Lash, C.M. Tolstoshev, L. Wagner, G.D. Schuler, R.L. Strausberg, and G.J. Riggins SAGEmap: a public gene expression resource Genome Res. 10 2000 1051 1060
62. P. Verschuure, C. Tatard, W.C. Boelens, J.F. Grongnet, and J.C. David Expression of small heat shock proteins HspB2, HspB8, Hsp20 and cvHsp in different tissues of the perinatal developing pig Eur. J. Cell Biol. 82 2003 523 530
63. P. Tallot, J.F. Grongnet, and J.C. David Dual perinatal and developmental expression of the small heat shock proteins alphaB-crystallin and Hsp27 in different tissues of the developing piglet Biol. Neonate 83 2003 281 288
64. Y. Sugiyama, A. Suzuki, M. Kishikawa, R. Akutsu, T. Hirose, and M.M. Waye Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation J. Biol. Chem. 275 2000 1095 1104
65. W.Y. Lam, S.K. Wing Tsui, P.T. Law, S.C. Luk, K.P. Fung, and C.Y. Lee Isolation and characterization of a human heart cDNA encoding a new member of the small heat shock protein family - HSPL27 Biochim. Biophys. Acta 1314 1996 120 124
66. W.C. Boelens, M.A. Van Boekel, and W.W. De Jong HspB3, the most deviating of the six known human small heat shock proteins Biochim. Biophys. Acta 1388 1998 513 516
67. G. Kappe, P. Verschuure, R.L. Philipsen, A.A. Staalduinen, P. Van de Boogaart, and W.C. Boelens Characterization of two novel human small heat shock proteins: protein kinase-related HspB8 and testis-specific HspB9 Biochim. Biophys. Acta 1520 2001 1 6
68. G. Kappe, E. Franck, P. Verschuure, W.C. Boelens, J.A. Leunissen, and W.W. de Jong The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10 Cell Stress Chaperones 8 2003 53 61
69. J.M. Fontaine, J.S. Rest, M.J. Welsh, and R. Benndorf The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins Cell Stress Chaperones 8 2003 62 69
70. C.C. Smith, Y.X. Yu, M. Kulka, and L. Aurelian A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells J. Biol. Chem. 275 2000 25690 25699
71. O. Gastmann, P. Burfeind, E. Gunther, H. Hameister, C. Szpirer, and S. Hoyer-Fender Sequence, expression, and chromosomal assignment of a human sperm outer dense fiber gene Mol. Reprod. Dev. 36 1993 407 418
72. K. Wang, and A. Spector ATP causes small heat shock proteins to release denatured protein Eur. J. Biochem. 268 2001 6335 6345
73. M. Ehrnsperger, S. Graber, M. Gaestel, and J. Buchner Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation EMBO J. 16 1997 221 229
74. X.Y. Wang, X. Chen, H.J. Oh, E. Repasky, L. Kazim, and J. Subjeck Characterization of native interaction of hsp110 with hsp25 and hsc70 FEBS Lett. 465 2000 98 102
75. A.J. de Ruijter, A.H. Van Gennip, H.N. Caron, S. Kemp, and A.B. Van Kuilenburg Histone deacetylases (HDACs): characterization of the classical HDAC family Biochem. J. 370 2003 737 749
76. P.A. Wade Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin Hum. Mol. Genet. 10 2001 693 698
77. J.P. Brady, D. Garland, Y. Duglas-Tabor, W.G. Robison Jr., A. Groome, and E.F. Wawrousek Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin Proc. Natl. Acad. Sci. USA 94 1997 884 889
78. X. Sun, J.M. Fontaine, J.S. Rest, E.A. Shelden, M.J. Welsh, and R. Benndorf Interaction of human HSP22 (HSPB8) with other small heat shock proteins J. Biol. Chem. 279 2004 2394 2402
79. K. Kato, H. Shinohara, N. Kurobe, Y. Inaguma, K. Shimizu, and K. Ohshima Tissue distribution and developmental profiles of immunoreactive alpha B crystallin in the rat determined with a sensitive immunoassay system Biochim. Biophys. Acta 1074 1991 201 208
80. I.J. Benjamin, J. Shelton, D.J. Garry, and J.A. Richardson Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development Dev. Dyn. 208 1997 75 84
81. K. Kato, S. Goto, Y. Inaguma, K. Hasegawa, R. Morishita, and T. Asano Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin J. Biol. Chem. 269 1994 15302 15309
82. M. Haslbeck, and J. Buchner Chaperone function of sHsps Prog. Mol. Subcell. Biol. 28 2002 37 59
83. N.B. Gusev, N.V. Bogatcheva, and S.B. Marston Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins Biochemistry (Mosc.) 67 2002 511 519
84. I.P. Van den, D.G. Norman, and R.A. Quinlan Molecular chaperones: small heat shock proteins in the limelight Curr. Biol. 9 1999 R103 R1035
85. H.M. Wain, M.J. Lush, F. Ducluzeau, V.K. Khodiyar, and S. Povey Genew: the Human Gene Nomenclature Database, 2004 updates Nucleic Acids Res 32 Database issue 2004 D255 D257
86. F.A. Van de Klundert, and M.L. Gijsen van den IPR, Snoeckx LH, de Jong WW. Alpha B-crystallin and hsp25 in neonatal cardiac cells - differences in cellular localization under stress conditions Eur. J. Cell Biol. 75 1998 38 45
87. B.Z. Simkhovich, P. Marjoram, C. Poizat, L. Kedes, and R.A. Kloner Brief episode of ischemia activates protective genetic program in rat heart: a gene chip study Cardiovasc. Res. 59 2003 450 459
88. G. Lutsch, R. Vetter, U. Offhauss, M. Wieske, H.J. Grone, and R. Klemenz Abundance and location of the small heat shock proteins HSP25 and alphaB-crystallin in rat and human heart Circulation 96 1997 3466 3476
89. B. Hoch, G. Lutsch, W.P. Schlegel, J. Stahl, G. Wallukat, and S. Bartel HSP25 in isolated perfused rat hearts: localization and response to hyperthermia Mol. Cell. Biochem. 160 1996 231 239 161
90. D.R. Ciocca, S. Oesterreich, G.C. Chamness, W.L. McGuire, and S.A. Fuqua Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review J. Natl. Cancer Inst. 85 1993 1558 1570
91. C.A. Efthymiou, M.M. Mocanu, J. de Belleroche, D.J. Wells, D.S. Latchmann, and D.M. Yellon Heat shock protein 27 protects the heart against myocardial infarction Basic Res. Cardiol. 99 2004 392 394
92. K. Kato, H. Ito, and Y. Inaguma Expression and phosphorylation of mammalian small heat shock proteins Prog. Mol. Subcell. Biol. 28 2002 129 150
93. C. Arnaud, M. Joyeux, C. Garrel, D. Godin-Ribuot, P. Demenge, and C. Ribuot Free-radical production triggered by hyperthermia contributes to heat stress-induced cardioprotection in isolated rat hearts Br. J. Pharmacol. 135 2002 1776 1782
94. Y. Inaguma, K. Hasegawa, S. Goto, H. Ito, and K. Kato Induction of the synthesis of hsp27 and alpha B crystallin in tissues of heat-stressed rats and its suppression by ethanol or an alpha 1-adrenergic antagonist J. Biochem. (Tokyo) 117 1995 1238 1243
95. M. Gaestel, W. Schroder, R. Benndorf, C. Lippmann, K. Buchner, and F. Hucho Identification of the phosphorylation sites of the murine small heat shock protein hsp25 J. Biol. Chem. 266 1991 14721 14724
96. J. Landry, H. Lambert, M. Zhou, J.N. Lavoie, E. Hickey, and L.A. Weber Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II J. Biol. Chem. 267 1992 794 803
97. K. Kato, H. Ito, I. Iwamoto, K. Lida, and Y. Inaguma Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27 Cell Stress Chaperones 6 2001 16 20
98. S.C. Benn, D. Perrelet, A.C. Kato, J. Scholz, I. Decosterd, and R.J. Mannion Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival Neuron 36 2002 45 56
99. K. Sakamoto, T. Urushidani, and T. Nagao Translocation of HSP27 to sarcomere induced by ischemic preconditioning in isolated rat hearts Biochem. Biophys. Res. Commun. 269 2000 137 142
100. P. Eaton, W.I. Awad, J.I. Miller, D.J. Hearse, and M.J. Shattock Ischemic preconditioning: a potential role for constitutive low molecular weight stress protein translocation and phosphorylation? J. Mol. Cell. Cardiol. 32 2000 961 971
101. A.P. Arrigo, C. Paul, C. Ducasse, O. Sauvageot, and C. Kretz-Remy Small stress proteins: modulation of intracellular redox state and protection against oxidative stress Prog. Mol. Subcell. Biol. 28 2002 171 184
102. J. Piatigorsky, and G.J. Wistow Enzyme/crystallins: gene sharing as an evolutionary strategy Cell 57 1989 197 199
103. T.D. Ingolia, and E.A. Craig Drosophila gene related to the major heat shock-induced gene is transcribed at normal temperatures and not induced by heat shock Proc. Natl. Acad. Sci. USA 79 1982 525 529
104. F.A. Van de Klundert, and W.W. de Jong The small heat shock proteins Hsp20 and alphaB-crystallin in cultured cardiac myocytes: differences in cellular localization and solubilization after heat stress Eur. J. Cell Biol. 78 1999 567 572
105. S.F. Lu, F.M. Pan, and S.H. Chiou Sequence analysis of frog alpha B-crystallin cDNA: sequence homology and evolutionary comparison of alpha A, alpha B and heat shock proteins Biochem. Biophys. Res. Commun. 216 1995 881 891
106. T.H. MacRae Structure and function of small heat shock/alpha-crystallin proteins: established concepts and emerging ideas Cell. Mol. Life Sci. 57 2000 899 913
107. C.M. Sax, and J. Piatigorsky Expression of the alpha-crystallin/small heat-shock protein/molecular chaperone genes in the lens and other tissues Adv. Enzymol. Relat. Areas Mol. Biol. 69 1994 155 201
108. S.P. Bhat, and C.N. Nagineni Alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues Biochem. Biophys. Res. Commun. 158 1989 319 325
109. W. Pipkin, J.A. Johnson, T.L. Creazzo, J. Burch, P. Komalavilas, and C. Brophy Localization, macromolecular associations, and function of the small heat shock-related protein HSP20 in rat heart Circulation 107 2003 469 476
110. K.S. Magabo, J. Horwitz, J. Piatigorsky, and M. Kantorow Expression of betaB(2)-crystallin mRNA and protein in retina, brain, and testis Invest. Ophthalmol. Vis. Sci. 41 2000 3056 3060
111. N. Gordon Alexander disease Eur. J. Paediatr. Neurol. 7 2003 395 399
112. P.S. Ray, J.L. Martin, E.A. Swanson, H. Otani, W.H. Dillmann, and D.K. Das Transgene overexpression of alphaB crystallin confers simultaneous protection against cardiomyocyte apoptosis and necrosis during myocardial ischemia and reperfusion FASEB J. 15 2001 393 402
113. J.P. Brady, D.L. Garland, D.E. Green, E.R. Tamm, F.J. Giblin, and E.F. Wawrousek AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach Invest. Ophthalmol. Vis. Sci. 42 2001 2924 2934
114. L. Carlsson, and L.E. Thornell Desmin-related myopathies in mice and man Acta Physiol. Scand. 171 2001 341 348
115. 2+ homoestasis during simulated ischemic/reperfusion Circulation 110 2004 III107 (abstract)
116. L.E. Morrison, R.J. Whittaker, R.E. Klepper, E.F. Wawrousek, and C.C. Glembotski Roles for alphaB-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model Am. J. Physiol. Heart Circ. Physiol. 286 2004 H847 H855
117. C.M. Rembold, and E. Kaufman Heat induced HSP20 phosphorylation without increased cyclic nucleotide levels in swine carotid media BMC Physiol. 3 2003 3
118. G.C. Fan, G. Chu, B. Mitton, Q. Song, Q. Yuan, and E.G. Kranias Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist-induced cardiac apoptosis Circ. Res. 94 2004 1474 1482
119. C.M. Brophy Stress and vascular disease at the cellular and molecular levels World J. Surg. 26 2002 779 782
120. R. Benndorf, X. Sun, R.R. Gilmont, K.J. Biederman, M.P. Molloy, and C.W. Goodmurphy HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27) J. Biol. Chem. 276 2001 26753 26761
121. T.K. Chowdary, B. Raman, T. Ramakrishna, and C.M. Rao Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity Biochem. J. 381 2004 379 387
122. C. Depre, M. Hase, V. Gaussin, A. Zajac, L. Wang, and L. Hittinger H11 kinase is a novel mediator of myocardial hypertrophy in vivo Circ. Res. 91 2002 1007 1014
123. Y.X. Yu, A. Heller, T. Liehr, C.C. Smith, and L. Aurelian Expression analysis and chromosome location of a novel gene (H11) associated with the growth of human melanoma cells Int. J. Oncol. 18 2001 905 911
124. N. Adachi, and M.R. Lieber Bidirectional gene organization: a common architectural feature of the human genome Cell 109 2002 807 809
125. R.J. Kay, R.J. Boissy, R.H. Russnak, and E.P. Candido Efficient transcription of a Caenorhabditis elegans heat shock gene pair in mouse fibroblasts is dependent on multiple promoter elements which can function bidirectionally Mol. Cell. Biol. 6 1986 3134 3143
126. N.D. Trinklein, S.F. Aldred, S.J. Hartman, D.I. Schroeder, R.P. Otillar, and R.M. Myers An abundance of bidirectional promoters in the human genome Genome Res. 14 2004 62 66
127. P. Verschuure, and Y. Croes van den IPR, Quinlan RA, de Jong WW, Boelens WC. Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition J. Mol. Cell. Cardiol. 34 2002 117 128
128. N. Golenhofen, M.D. Perng, R.A. Quinlan, and D. Drenckhahn Comparison of the small heat shock proteins alphaB-crystallin, MKBP, HSP25, HSP20, and cvHSP in heart and skeletal muscle Histochem Cell Biol 2004
129. A.N. Srinivasan, C.N. Nagineni, and S.P. Bhat Alpha A-crystallin is expressed in non-ocular tissues J. Biol. Chem. 267 1992 23337 23341
130. K. Kato, H. Shinohara, N. Kurobe, S. Goto, Y. Inaguma, and K. Ohshima Immunoreactive alpha A crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method Biochim. Biophys. Acta 1080 1991 173 180
131. C.E. Egwuagu, and A.B. Chepelinsky Extralenticular expression of the alpha A-crystallin promoter/gamma interferon transgene Exp. Eye Res. 64 1997 491 495
132. R. Jaenicke, and C. Slingsby Lens crystallins and their microbial homologs: structure, stability, and function Crit. Rev. Biochem. Mol. Biol. 36 2001 435 499
133. F.A. Van der Hoorn, H.A. Tarnasky, and S.K. Nordeen A new rat gene RT7 is specifically expressed during spermatogenesis Dev. Biol. 142 1990 147 154
134. N.A. Higgy, T. Pastoor, C. Renz, H.A. Tarnasky, and F.A. Van der Hoorn Testis-specific RT7 protein localizes to the sperm tail and associates with itself Biol. Reprod. 50 1994 1357 1366
135. A.P. Arrigo, and W.J. Welch Characterization and purification of the small 28,000-Da mammalian heat shock protein J. Biol. Chem. 262 1987 15359 15369
136. G.P. Thomas, W.J. Welch, M.B. Mathews, and J.R. Feramisco Molecular and cellular effects of heat-shock and related treatments of mammalian tissue-culture cells Cold Spring Harb. Symp. Quant. Biol. 46 Pt 2 1982 985 996
137. R. Chenna, H. Sugawara, T. Koike, R. Lopez, T.J. Gibson, and D.G. Higgins Multiple sequence alignment with the Clustal series of programs Nucleic Acids Res. 31 2003 3497 3500
138. R.D. Page TreeView: an application to display phylogenetic trees on personal computers Comput. Appl. Biosci. 12 1996 357 358