Copper transfer studies between the N-terminal copper binding domains one and four of human Wilson protein

Biochimica et Biophysica Acta - General Subjects

Volumn 1760, Issue 6, 2006, Pages 907-912

  Bunce, Jennifer ^a   Achila, David ^a   Hetrick, Evan ^a   Lesley, Leighann ^a   Huffman, David L ^a  

^a WESTERN MICHIGAN UNIVERSITY   (United States)

Author keywords

ATP7B; Copper transfer; Metal binding domain; Wilson protein

Indexed keywords

COPPER; PROTEIN; UNCLASSIFIED DRUG; WILSON 1 PROTEIN; WILSON 3 PROTEIN; WILSON 4 PROTEIN; WILSON 5 PROTEIN; WILSON 6 PROTEIN; WILSON PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; HYPOTHESIS; IN VIVO STUDY; ION EXCHANGE CHROMATOGRAPHY; ISOELECTRIC POINT; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ADENOSINE TRIPHOSPHATASES; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; COPPER; HUMANS; ISOELECTRIC POINT; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 33744527165     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2006.02.005     Document Type: Article

References (38)

1. Huffman D.L., and O'Halloran T.V. Function, structure, and mechanism of intracellular copper trafficking proteins. Annu. Rev. Biochem. 70 (2001) 677-701
2. Kuo Y.M., Zhou B., Cosco D., and Gitschier J. The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 6836-6841
3. Zhou B., and Gitschier J. hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 7481-7486
4. Casareno R.L., Waggoner D., and Gitlin J.D. The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase. J. Biol. Chem. 273 (1998) 23625-23628
5. Horng Y.C., Cobine P.A., Maxfield A.B., Carr H.S., and Winge D.R. Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. J. Biol. Chem. 279 (2004) 35334-35340
6. Klomp L.W.J., Lin S.-J., Yuan D.S., Klausner R.D., Culotta V.C., and Gitlin J.D. Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis. J. Biol. Chem. 272 (1997) 9221-9226
7. Hamza I., Schaefer M., Klomp L.W., and Gitlin J.D. Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 13363-13368
8. Larin D., Mekios C., Das K., Ross B., Yang A.S., and Gilliam T.C. Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p. J. Biol. Chem. 274 (1999) 28497-28504
9. Pufahl R.A., Singer C.P., Peariso K.L., Lin S.-J., Schimdt P., Culotta V.C., Penner-Hahn J.E., and O'Halloran T.V. Metal ion chaperone function of the soluble Cu(I) receptor Atx1. Science 278 (1997) 853-856
10. Huffman D.L., and O'Halloran T.V. Energetics of copper trafficking between the Atx1 metallochaperone and the intracellular copper transporter, Ccc2. J. Biol. Chem. 275 (2000) 18611-18614
11. Hung I., Suzuki M., Yamaguchi Y., Yuan D.S., Klausner R.D., and Gitlin J.D. Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 272 (1997) 21461-21466
12. Paynter J.A., Grimes A., Lockhart P., and Mercer J.F. Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels. FEBS Lett. 351 (1994) 186-190
13. Schaefer M., Hopkins R.G., Failla M.L., and Gitlin J.D. Hepatocyte-specific localization and copper-dependent trafficking of the Wilson's disease protein in the liver. Am. J. Physiol. 276 (1999) G639-G646
14. Yamaguchi Y., Heiny M.E., Suzuki M., and Gitlin J.D. Biochemical characterization and intracellular localization of the Menkes disease protein. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 14030-14035
15. Petris M.J., Mercer J.F., Culvenor J.G., Lockhart P., Gleeson P.A., and Camakaris J. Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. EMBO J. 15 (1996) 6084-6095
16. Terada K., Nakako T., Yang X.L., Iida M., Aiba N., Minamiya Y., Nakai M., Sakaki T., Miura N., and Sugiyama T. Restoration of holoceruloplasmin synthesis in LEC rat after infusion of recombinant adenovirus bearing WND cDNA. J. Biol. Chem. 273 (1998) 1815-1820
17. Terada K., Aiba N., Yang X.L., Iida M., Nakai M., Miura N., and Sugiyama T. Biliary excretion of copper in LEC rat after introduction of copper transporting P-type ATPase, ATP7B. FEBS Lett. 448 (1999) 53-56
18. Payne A.S., and Gitlin J.D. Functional expression of the Menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. J. Biol. Chem. 273 (1998) 3765-3770
19. Forbes J.R., Hsi G., and Cox D.W. Role of the copper-binding domain in the copper transport function of ATP7B, the P-type ATPase defective in Wilson disease. J. Biol. Chem. 274 (1999) 12408-12413
20. Cater M.A., Forbes J., La Fontaine S., Cox D., and Mercer J.F. Intracellular trafficking of the human Wilson protein: the role of the six N-terminal metal-binding sites. Biochem. J. 380 (2004) 805-813
21. Strausak D., La Fontaine S., Hill J., Firth S.D., Lockhart P.J., and Mercer J.F. The role of GMXCXXC metal binding sites in the copper-induced redistribution of the Menkes protein. J. Biol. Chem. 274 (1999) 11170-11177
22. Arnesano F., Banci L., Bertini I., Ciofi-Baffoni S., Molteni E., Huffman D.L., and O'Halloran T.V. Metallochaperones and metal-transporting ATPases: a comparative analysis of sequences and structures. Genome Res. 12 (2002) 255-271
23. Banci L., Bertini I., Del Conte R., D'Onofrio M., and Rosato A. Solution structure and backbone dynamics of the Cu(I) and apo forms of the second metal-binding domain of the Menkes protein ATP7A. Biochemistry 43 (2004) 3396-3403
24. Gitschier J., Moffat B., Reilly D., Wood W.I., and Fairbrother W.J. Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase. Nat. Struct. Biol. 5 (1998) 47-54
25. Banci L., Bertini I., Ciofi-Baffoni S., Chasapis C.T., Hadjiliadis N., and Rosato A. An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein. FEBS J. 272 (2005) 865-871
26. van Dongen E.M., Klomp L.W., and Merkx M. Copper-dependent protein-protein interactions studied by yeast two-hybrid analysis. Biochem. Biophys. Res. Commun. 323 (2004) 789-795
27. Walker J.M., Huster D., Ralle M., Morgan C.T., Blackburn N.J., and Lutsenko S. The N-terminal metal-binding site 2 of the Wilson's disease protein plays a key role in the transfer of copper from Atox1. J. Biol. Chem. 279 (2004) 15376-15384
28. Arnesano F., Banci L., Bertini I., Cantini F., Ciofi-Baffoni S., Huffman D.L., and O'Halloran T.V. Characterization of the binding interface between the copper chaperone Atx1 and the first cytosolic domain of Ccc2 ATPase. J. Biol. Chem. 276 (2001) 41365-41376
29. Crowley P.B., and Ubbink M. Close encounters of the transient kind: protein interactions in the photosynthetic redox chain investigated by NMR spectroscopy. Acc. Chem. Res. 36 (2003) 723-730
30. Wernimont A.K., Yatsunyk L.A., and Rosenzweig A.C. Binding of copper(I) by the Wilson disease protein and its copper chaperone. J. Biol. Chem. 279 (2004) 12269-12276
31. Loudianos G., Dessi V., Lovicu M., Angius A., Nurchi A., Sturniolo G.C., Marcellini M., Zancan L., Bragetti P., Akar N., Yagci R., Vegnente A., Cao A., and Pirastu M. Further delineation of the molecular pathology of Wilson disease in the Mediterranean population. Hum. Mutat. 12 (1998) 89-94
32. Arnesano F., Banci L., Bertini I., and Bonvin A.M. A docking approach to the study of copper trafficking proteins; interaction between metallochaperones and soluble domains of copper ATPases. Structure (Camb) 12 (2004) 669-676
33. Rosenzweig A.C. Copper delivery by metallochaperone proteins. Acc. Chem. Res. 34 (2001) 119-128
34. Achila D., Banci L., Bertini I., Bunce J., Ciofi-Baffoni S., and Huffman D.L. Structure of human Wilson protein domains 5 and 6 and their interplay with domain 4 and the copper chaperone HAH1 in copper uptake. Proc. Nat. Acad. Sci. U. S. A. 103 (2006) 5729-5734
35. Ralle M., Lutsenko S., and Blackburn N.J. X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu(I) center capable of adduct formation with exogenous thiols and phosphines. J. Biol. Chem. 278 (2003) 23163-23170
36. Ralle M., Cooper M.J., Lutsenko S., and Blackburn N.J. The Menkes disease protein binds copper via novel 2-coordinate Cu(I)-cysteinates in the N-terminal domain. J. Am. Chem. Soc. 120 (1998) 13525-13526
37. DiDonato M., Hsu H.F., Narindrasorasak S., Que Jr. L., and Sarkar B. Copper-induced conformational changes in the N-terminal domain of the Wilson disease copper-transporting ATPase. Biochemistry 39 (2000) 1890-1896
38. Jones C.E., Daly N.L., Cobine P.A., Craik D.J., and Dameron C.T. Structure and metal binding studies of the second copper binding domain of the Menkes ATPase. J. Struct. Biol. 143 (2003) 209-218