The N-terminal Metal-binding Site 2 of the Wilson's Disease Protein Plays a Key Role in the Transfer of Copper from Atox1

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15376-15384

  Walker, Joel M ^a   Huster, Dominik ^a   Ralle, Martina ^a   Morgan, Clinton T ^a   Blackburn, Ninian J ^a   Lutsenko, Svetlana ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CATALYST ACTIVITY; DISEASES; METABOLISM; PROTEINS; X RAY ANALYSIS;

METABOLIC DISORDERS; WILSON'S DISEASE PROTEIN (WNDP);

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE; CHAPERONE; CHELATING AGENT; PROTEIN; PROTEIN ATOX1; UNCLASSIFIED DRUG; WILSON DISEASE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COMPETITIVE INHIBITION; COMPLEX FORMATION; COPPER METABOLISM; METABOLIC DISORDER; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; ROENTGEN SPECTROSCOPY; SITE DIRECTED MUTAGENESIS; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CATALYSIS; CATION TRANSPORT PROTEINS; CELL LINE; CELL MEMBRANE; COPPER; CYSTEINE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; HUMANS; INSECTS; IONS; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SCATTERING, RADIATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, X-RAY EMISSION;

EID: 2442572209     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400053200     Document Type: Article

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