Synthesis of (Z)-alkene and (E)-fluoroalkene-containing diketopiperazine mimetics utilizing organocopper-mediated reduction-alkylation and diastereoselectivity examination using DFT calculations

Journal of Organic Chemistry

Volumn 71, Issue 11, 2006, Pages 4118-4129

  Niida, Ayumu ^a   Mizumoto, Makiko ^a   Narumi, Tetsuo ^a   Inokuchi, Eriko ^a   Oishi, Shinya ^a   Ohno, Hiroaki ^a   Otaka, Akira ^a,b   Kitaura, Kazuo ^a   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLLITHIUM COMPLEXES; BENZYL SIDE CHAIN; DIASTEREOSELECTIVITY EXAMINATION; DIKETOPIPERAZINE MIMETICS;

ALKYLATION; COPPER; ISOMERS; NITROGEN COMPOUNDS; REACTION KINETICS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

OLEFINS;

ACETIC ACID DERIVATIVE; ALKENE DERIVATIVE; COPPER DERIVATIVE; LACTAM DERIVATIVE; LITHIUM DERIVATIVE; ORGANOCOPPER DERIVATIVE; PIPERAZINEDIONE; REAGENT; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL STRUCTURE; CIS ISOMER; COMPLEX FORMATION; DENSITY FUNCTIONAL THEORY; DIASTEREOISOMER; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY; STEREOSPECIFICITY; STRUCTURE ANALYSIS; SYNTHESIS; TRANS ISOMER;

ALKENES; COPPER; DIKETOPIPERAZINES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERAZINES;

EID: 33646916569     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060202z     Document Type: Article

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