Electrostatic versus steric effects in peptidomimicry: Synthesis and secondary structure analysis of gramicidin S analogues with (E)-alkene peptide isosteres

Journal of the American Chemical Society

Volumn 127, Issue 16, 2005, Pages 5742-5743

  Xiao, Jingbo ^a   Weisblum, Bernard ^b   Wipf, Peter ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; GRAMICIDIN S;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC ACTIVITY; MOLECULAR MIMICRY; OXIDATION; PHASE TRANSITION; PROTEIN SECONDARY STRUCTURE; SAPONIFICATION; STEREOCHEMISTRY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ALKENES; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; GRAMICIDIN; MODELS, MOLECULAR; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, SECONDARY; STEREOISOMERISM;

EID: 17744380977     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja051002s     Document Type: Article

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