SmI2-Mediated Reduction of γ,γ-Difluoro-α ,β-enoates with Application to the Synthesis of Functionalized (Z)-Fluoroalkene-Type Dipeptide Isosteres

Journal of Organic Chemistry

Volumn 69, Issue 5, 2004, Pages 1634-1645

  Otaka, Akira ^a   Watanabe, Junko ^a   Yukimasa, Akira ^a   Sasaki, Yoshikazu ^a   Watanabe, Hideaki ^a   Kinoshita, Takayoshi ^b   Oishi, Shinya ^a   Tamamura, Hirokazu ^a   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CHROMATOGRAPHY; REACTION KINETICS; REDUCTION; SAMARIUM COMPOUNDS;

MIMETICS; REFORMATSKY REACTIONS; TWO-ELECTRON TRANSFER;

PROTEINS;

ALKENE DERIVATIVE; BETA AMINO ACID; CARBONYL DERIVATIVE; DIPEPTIDE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 2 (1 HYDROXY 1 METHYLETHYL) 6 PHENYLHEX 3 ENOATE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 2 HYDROXYMETHYL 6 PHENYLHEX 3 ENOATE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 6 METHYLHEPT 3 ENOATE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 6 PHENYLHEX 3 ENOATE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4,4 DIFLUORO 6 METHYLHEPT 2 ENOATE; ETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4,4 DIFLUORO 6 PHENYLHEX 2 ENOATE; FLUORENE DERIVATIVE; LACTONE DERIVATIVE; METHYL 2 BENZYLSULFANYLMETHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 6 PHENYLHEX 3 ENOATE; METHYL 5 [N (TERT BUTOXYCARBONYL)AMINO] 4 FLUORO 2 (2 METHYLPROPYL) 6 PHENYLHEX 3 ENOATE; REAGENT; SAMARIUM DIIODIDE; UNCLASSIFIED DRUG; ALKENE; FLUORINATED HYDROCARBON; IMINE; IODIDE; SAMARIUM;

ALDOL REACTION; ARTICLE; CATALYSIS; CHIRALITY; CHROMATOGRAPHY; ELECTRON TRANSPORT; REDUCTION; REFORMATSKY REACTION; RING OPENING; SYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

ALKENES; DIPEPTIDES; HYDROCARBONS, FLUORINATED; IMINES; IODIDES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SAMARIUM; STEREOISOMERISM;

EID: 1442324529     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo035709d     Document Type: Article

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