Chlamydial DNA polymerase I can bypass lesions in vitro

Biochemical and Biophysical Research Communications

Volumn 345, Issue 3, 2006, Pages 1083-1091

  Liu, Xipeng ^a   Hou, Jingli ^a   Liu, Jianhua ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

3 exonuclease; C. pneumoniae; DNA polymerase I; Translesion synthesis

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DEOXYINOSINE; DEOXYRIBOSE; DEOXYURIDINE; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE BETA; SPLEEN EXONUCLEASE; TETRAHYDROFURAN; THYMIDINE;

AMINO ACID SEQUENCE; APURINIC SITE; APYRIMIDINIC SITE; ARTICLE; BASE MISPAIRING; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME PURIFICATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CHLAMYDOPHILA PNEUMONIAE; DNA; DNA DAMAGE; DNA POLYMERASE I; DNA PRIMERS; EXONUCLEASES; KINETICS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 33646844750     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.05.021     Document Type: Article

References (20)

1. Savic D.J., Jankovic M., and Kostic T. Cellular role of DNA polymerase I. J. Basic Microbiol. 30 (1990) 769-784
2. Thommes P., and Hubscher U. Eukaryotic DNA replication. Enzymes and proteins acting at the fork. Eur. J. Biochem. 194 (1990) 699-712
3. Harrison L., Hatahet Z., and Wallace S.S. In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J. Mol. Biol. 290 (1999) 667-684
4. Ishimi Y., Claude A., Bullock P., and Hurwitz J. Complete enzymatic synthesis of DNA containing the SV40 origin of replication. J. Biol. Chem. 263 (1988) 19723-19733
5. Lage C., de Padula M., de Alencar T.A., da Fonseca Goncalves S.R., da Silva Vidal L., Cabral-Neto J., and Leitao A.C. New insights on how nucleotide excision repair could remove DNA adducts induced by chemotherapeutic agents and psoralens plus UV-A (PUVA) in Escherichia coli cells. Mutat. Res. 544 (2003) 143-157
6. Lawyer F.C., Stoffel S., Saiki R.K., Myambo K., Drummond R., and Gelfand D.H. Isolation, characterization, and expression in Escherichia coli of the DNA polymerase gene from Thermus aquaticus. J. Biol. Chem. 264 (1989) 6427-6437
7. Dabrowski S., and Kur J. Cloning and expression in Escherichia coli of the recombinant his-tagged DNA polymerases from Pyrococcus furiosus and Pyrococcus woesei. Protein Expr. Purif. 14 (1998) 131-138
8. Diaz A., Pons M.E., Lacks S.A., and Lopez P. Streptococcus pneumoniae DNA polymerase I lacks 3′-to-5′ exonuclease activity: localization of the 5′-to-3′ exonucleolytic domain. J. Bacteriol. 174 (1992) 2014-2024
9. Bernad A., Blanco L., Lazaro J.M., Martin G., and Salas M. A conserved 3′-5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Cell 59 (1989) 219-228
10. Khare V., and Eckert K.A. The proofreading 3′-5′ exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Mutat. Res. 510 (2002) 45-54
11. Napolitano R., Janel-Bintz R., Wagner J., and Fuchs R.P. All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis. EMBO J. 19 (2000) 6259-6265
12. Campbell L.A., and Kuo C.C. Chlamydia pneumoniae-an infectious risk factor for atherosclerosis?. Nat. Rev. Microbiol. 2 (2004) 23-32
13. Liu X.P., and Liu J.H. Cloning, expression, and characterization of uracil-DNA glycosylase of Chlamydia pneumoniae in Escherichia coli. Protein Expr. Purif. 35 (2004) 46-53
14. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25 (1997) 4876-4882
15. Belousova E.A., Rechkunova N.I., and Lavrik O.I. Thermostable DNA polymerases can perform translesion synthesis using 8-oxoguanine and tetrahydrofuran-containing DNA templates. Biochim. Biophys. Acta. 1764 (2006) 97-104
16. Goodman M.F. Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Annu. Rev. Biochem. 71 (2002) 17-50
17. Tang M., Pham P., Shen X., Taylor J.S., O'Donnell M., Woodgate R., and Goodman M.F. Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature 404 (2000) 1014-1018
18. Pham P., Bertram J.G., O'Donnell M., Woodgate R., and Goodman F. A model for SOS-lesion-targeted mutations in Escherichia coli. Nature 409 (2001) 366-370
19. Becherel O.J., Fuchs R.P., and Wagner J. Pivotal role of the beta-clamp in translesion DNA synthesis and mutagenesis in E. coli cells. DNA Repair 1 (2002) 703-708
20. Lopez de Saro F.J., Georgescu R.E., and O'Donnell M. A peptide switch regulates DNA polymerase processivity. Proc. Natl. Acad. Sci. USA 100 (2003) 14689-14694