QSAR modeling of the inhibition of Glycogen Synthase Kinase-3

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 14, 2006, Pages 4987-5002

  Katritzky, Alan R ^a   Pacureanu, Liliana M ^a   Dobchev, Dimitar A ^a,d   Fara, Dan C ^a   Duchowicz, Pablo R ^b   Karelson, Mati ^c,d  

^a University of Florida ^*  (United States)

^b INSTITUTO DE INVESTIGACIONES FISICOQUÍMICAS TEÓRICAS Y APLICADAS INIFTA   (Argentina)

^c TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^d UNIVERSITY OF TARTU   (Estonia)

Author keywords

Artificial neural network; CODESSA PRO; Inhibitory activity IC50; Kinase; Stepwise regression

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3;

ARTICLE; CHEMICAL STRUCTURE; IC 50; MATHEMATICAL ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LINEAR MODELS; MODELS, CHEMICAL; NEURAL NETWORKS (COMPUTER); NONLINEAR DYNAMICS; PROTEIN KINASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE;

EID: 33646780525     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.03.009     Document Type: Article

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