Modafinil in treatment of fatigue in multiple sclerosis: Results of an open-label study

Journal of Neurology

Volumn 249, Issue 8, 2002, Pages 983-987

  Zifko, Udo A ^a,b   Rupp, Monika ^a,b   Schwarz, Sigrid ^a,b   Zipko, Harald T ^b   Maida, Eva M ^c  

^a Rehabilitationsklinik Pirawarth   (Austria)

^b Arbeitskreis für Klinische Forschung in der Neurorehabilitation   (Austria)

^c Evangelisches Krankenhaus Vienna   (Austria)

Author keywords

Daytime sleepiness; Fatigue; Modafinil; Multiple sclerosis

Indexed keywords

MODAFINIL;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE CLASSIFICATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FATIGUE; FEMALE; HUMAN; MALE; MULTICENTER STUDY; MULTIPLE SCLEROSIS; NARCOLEPSY; NERVOUSNESS; PATIENT SATISFACTION; PRIORITY JOURNAL; QUALITY OF LIFE; SCORING SYSTEM; SELF EVALUATION; SOMNOLENCE; TREATMENT OUTCOME; VERTIGO;

ADULT; ANXIETY; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; DIZZINESS; FATIGUE; FEMALE; HUMANS; MALE; MULTIPLE SCLEROSIS;

EID: 0036038978     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-002-0765-6     Document Type: Article

References (43)

1. Fatigue in multiple sclerosis: Cross-sectional correlation with brain MRI findings in 71 patients
2. Fatigue in multiple sclerosis and its relationship to depression and neurologic disability
3. Health-related quality of life effects of modafinil for treatment of narcolepsy
4. German version of the epworth sleepiness scale
5. The management of multiple sclerosis patients
6. Physiopathology and treatment of fatigue in multiple sclerosis
7. Fatigue in multiple sclerosis compared with chronic fatigue syndrome: A quantitative assessment
8. Central alpha-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil: Studies with experimental animals
9. Combined MAOI, TCA, and direct stimulant therapy of treatment-resistant depression
10. The impact of fatigue on patients with multiple sclerosis
11. Symptomatic fatigue in multiple sclerosis
12. Working memory impairment among persons with chronic progressive multiple sclerosis
13. Successful treatment of excessive daytime sleepiness in Parkinson's disease with modafinil
14. Modalities of fatigue in multiple sclerosis: Correlation with clinical and biological factors
15. Fatigue in MS: Cross-sectional correlation with brain MRI
16. Fatigue in multiple sclerosis: Relationship to depression, disability, and disease pattern
17. The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematodes
18. Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
19. Fatigue and magnetic resonance imaging activity in multiple sclerosis
20. Modafinil augmentation of antidepressant treatment in depression
21. Genetic and familial aspects of narcolepsy
22. Modafinil binds to the dopamine uptake carrier site with low affinity
23. Excessive muscular fatigue in patients with spastic paraparesis
24. Hypocretin (orexin) deficiency in human narcolepsy
25. Modafinil as adjunct therapy for daytime sleepiness in obstructive sleep apnea
26. Impact of aerobic training on fitness and quality of life in multiple sclerosis
27. Modafinil, d-amphetamine and placebo during 64 hours of sustained mental work. I. Effects on mood, fatigue, cognitive performance and body temperature
28. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
29. Modafinil - Efficacy and safety for the treatment of fatigue in patients with multiple sclerosis
30. Effects of modafinil in children with attention-deficit/hyperactivity disorder: An open-label study
31. Differential effects of the new central adrenergic agonist modafinil and d-amphetamine on sleep and early morning behaviour in elderlies
32. Fatigue in patients with multiple sclerosis: Motor pathway conduction and event-related potentials
33. Hypothalamic arousal regions are activated during modafinil-induced wakefulness
34. Modafinil in the treatment of idiopathic hypersomnia
35. Evidence of an abnormal intramuscular component of fatigue in multiple sclerosis
36. Fatigue in multiple sclerosis. Evaluation and a new pharmacological approach
37. Modafinil for the treatment of pathological somnolence in narcolepsy
38. Fatigue in multiple sclerosis: Interrelations between fatigue complaints, cerebral MRI abnormalities and neurological disability
39. Dopaminergic role in stimulant-induced wake-fulness
40. Erfolgreiche behandlung der tagesmüdigkeit bei multipler sklerose mit modafinil - Ein fallbericht
41. Successful treatment of fatigue in multiple sclerosis with modafinil
42. Sexual dysfunction in multiple sclerosis: II. Correlation analysis