The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism

European Journal of Pharmacology

Volumn 306, Issue 1-3, 1996, Pages 33-39

  Ferraro, Luca ^a   Tanganelli, Sergio ^b   O'Connor, William Thomas ^c   Antonelli, Tiziana ^a   Rambert, Francis ^d   Fuxe, Kjell ^e  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d Neuropsychopharmacologie   (France)

^e KAROLINSKA INSTITUTE   (Sweden)

Author keywords

dopamine release; GABA ( aminobutyric acid); microdialysis; modafinil; nucleus accumbens

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; BICUCULLINE; DOPAMINE; GABA UPTAKE INHIBITOR; GABAERGIC RECEPTOR AFFECTING AGENT; MODAFINIL; MUSCIMOL; PHACLOFEN; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID RELEASE; ALERTNESS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; GABAERGIC TRANSMISSION; INTRACEREBRAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PERFUSION; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 18344417904     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00182-3     Document Type: Article

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