Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms

Clinical Infectious Diseases

Volumn 42, Issue 11, 2006, Pages 1561-1569

  Chen, Wei Ju ^a   Yang, Jyh Yuan ^a   Lin, Jih Hui ^a   Fann, Cathy S J ^a   Osyetrov, Valeriy ^a   King, Chwan Chuen ^a   Chen, Yi Ming Arthur ^b   Chang, Hsiao Liang ^a   Kuo, Hung Wei ^a   Liao, Fong ^a   Ho, Mei Shang ^a,b,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c ACADEMIA SINICA   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 1ALPHA; TRANSCRIPTION FACTOR RELB;

ADULT; AGE; AGED; ALLELE; ARTICLE; DISEASE ASSOCIATION; FEMALE; GENDER; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INFLUENZA VIRUS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; STRAIN IDENTIFICATION; TAIWAN; VIRUS DETECTION;

ADULT; AGED; FEMALE; FIBRINOGEN; HUMANS; INTERLEUKIN-1; INTERLEUKIN-18; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NASOPHARYNX; POLYMORPHISM, GENETIC; SARS VIRUS; TRANSCRIPTION FACTOR RELB; VIRAL LOAD; VIRUS SHEDDING;

EID: 33646721954     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/503843     Document Type: Article

References (46)

1. Booth CM, Matukas LM, Tomlinson GA, et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 2003; 289:2801-9.
2. Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 2003; 361:1767-72.
3. Rainer TH, Chan PK, Ip M, et al. The spectrum of severe acute respiratory syndrome-associated coronavirus infection. Ann Intern Med 2004; 140:614-9.
4. Tsui PT, Kwok ML, Yuen H, Lai ST. Severe acute respiratory syndrome: clinical outcome and prognostic correlates. Emerg Infect Dis 2003; 9: 1064-9.
5. Cheung OY, Chan JW, Ng CK, Koo CK. The spectrum of pathological changes in severe acute respiratory syndrome (SARS). Histopathology 2004; 45:119-24.
6. Wong KT, Antonio GE, Hui DS, et al. Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients. Radiology 2003; 228:401-6.
7. Wong CK, Lam CW, Wu AK, et al. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol 2004; 136:95-103.
8. Jiang Y, Xu J, Zhou C, et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med 2005; 171:850-7.
9. Huang KJ, Su IJ, Theron M, et al. An interferon-gamma-related cytokine storm in SARS patients. J Med Virol 2005; 75:185-94.
10. Chu CM, Poon LL, Cheng VC, et al. Initial viral load and the outcomes of SARS. CMAJ 2004; 171:1349-52.
11. Cheng VC, Hung IF, Tang BS, et al. Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome. Clin Infect Dis 2004; 38:467-75.
12. Ng EK, Hui DS, Chan KC, et al. Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome. Clin Chem 2003; 49: 1976-80.
13. Wang WK, Chen SY, Liu IJ, et al. Detection of SARS-associated coronavirus in throat wash and saliva in early diagnosis. Emerg Infect Dis 2004; 10:1213-9.
14. Ding YQ, Wang HJ, Shen H, et al. Study on etiology and pathology of severe acute respiratory syndrome [in Chinese]. Zhonghua Bing Li Xue Za Zhi 2003; 32:195-200.
15. Farcas GA, Poutanen SM, Mazzulli T, et al. Fatal severe acute respiratory syndrome is associated with multiorgan involvement by coronavirus. J Infect Dis 2005; 191:193-7.
16. Wang CH, Liu CY, Wan YL, et al. Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS. Respir Res 2005; 6:42.
17. Chu CM, Leung WS, Cheng VC, et al. Duration of RT-PCR positivity in severe acute respiratory syndrome. Eur Respir J 2005; 25:12-4.
18. Hung IF, Cheng VC, Wu AK, et al. Viral loads in clinical specimens and SARS manifestations. Emerg Infect Dis 2004; 10:1550-7.
19. Mazzulli T, Farcas GA, Poutanen SM, et al. Severe acute respiratory syndrome-associated coronavirus in lung tissue. Emerg Infect Dis 2004; 10:20-4.
20. Wu HS, Chiu SC, Tseng TC, et al. Serologic and molecular biologic methods for SARS-associated coronavirus infection, Taiwan. Emerg Infect Dis 2004; 10:304-10.
21. Ho M-S, Chen W-J, Chen H-Y, et al. Neutralizing antibody response and SARS severity. Emerg Infect Dis 2005; 11:1730-7.
22. Pan WH, Fann CSJ, Wu JY, et al. Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations. Hum Hered 2006; 61:27-30.
23. Chen WJ, Fann CSJ, Osyetrov V, Ho MS. Table 1: the 64 candidate genes. Available at: http://www.ibms.sinica.edu.tw/html/pi/msho_download/ Table%201_SARS%20&%20SNP_950127.pdf. Accessed 27 January 2006.
24. HUGO Gene Nomenclature Committee. Searchgenes. Available at: http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/searchgenes.pl. Accessed 31 November 2005.
25. Ott J. Strategies for characterizing highly polymorphic markers in human gene mapping. Am J Hum Genet 1992; 51:283-90.
26. Stephens M, et al. PHASEv2. Available at: http://depts.washington.edu/ ventures/UW_Technology/Express_Licenses/PHASEv2.php. Accessed 31 January 2005.
27. Weinstock JV, Blum A, Metwali A, Elliott D, Arsenescu R. IL-18 and IL-12 signal through the NF-κB pathway to induce NK-1R expression on T cells. J Immunol 2003; 170:5003-7.
28. Sareneva T, Julkunen I, Matikainen S. IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells. J Immunol 2000; 165:1933-8.
29. Wickremasinghe MI, Thomas LH, Friedland JS. Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-κB-dependent network. J Immunol 1999; 163:3936-47.
30. Ghosh S, May MJ, Kopp EB. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16:225-60.
31. Trebilcock GU, Ponnappan U. Induction and regulation of NFκB during aging: role of protein kinases. Clin Immunol Immunopathol 1996; 79:87-91.
32. Allan SM, Tyrrell PJ, Rothwell NJ. Interleukin-1 and neuronal injury. Nat Rev Immunol 2005; 5:629-40.
33. Van Der Sluijs KF, Van Elden LJ, Arens R, et al. Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus. Immunology 2005; 114:112-20.
34. Price P, James I, Fernandez S, French MA. Alleles of the gene encoding IL-1α may predict control of plasma viraemia in HIV-1 patients on highly active antiretroviral therapy. AIDS 2004; 18:1495-501.
35. Murakami Y, Otsuki M, Kusumoto K, Takeuchi S, Takahashi S. Estrogen inhibits interleukin-18 mRNA expression in the mouse uterus. J Reprod Dev 2005; 51:639-47.
36. Beagley KW, Gockel CM. Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone. FEMS Immunol Med Microbiol 2003; 38:13-22.
37. Morales-Montor J, Chavarria A, De Leon MA, et al. Host gender in parasitic infections of mammals: an evaluation of the female host supremacy paradigm. J Parasitol 2004; 90:531-46.
38. Mo R, Chen J, Grolleau-Julius A, Murphy HS, Richardson BC, Yung RL. Estrogen regulates CCR gene expression and function in T lymphocytes. J Immunol 2005; 174:6023-9.
39. Karlberg J, Chong DS, Lai WY. Do men have a higher case fatality rate of severe acute respiratory syndrome than women do? Am J Epidemiol 2004; 159:229-31.
40. Clark DA, Foerster K, Fung L, et al. The fgl2 prothrombinase/fibroleukin gene is required for lipopolysaccharide-triggered abortions and for normal mouse reproduction. Mol Hum Reprod 2004; 10:99-108.
41. Levy GA, Liu M, Ding J, et al. Molecular and functional analysis of the human prothrombinase gene (HFGL2) and its role in viral hepatitis. Am J Pathol 2000; 156:1217-25.
42. Marsden PA, Ning Q, Fung LS, et al. The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis. J Clin Invest 2003; 112:58-66.
43. Ning Q, Lakatoo S, Liu M, et al. Induction of prothrombinase fgl2 by the nucleocapsid protein of virulent mouse hepatitis virus is dependent on host hepatic nuclear factor-4α. J Biol Chem 2003; 278:15541-9.
44. Marazzi S, Blum S, Hartmann R, et al. Characterization of human fibroleukin, a fibrinogen-like protein secreted by T lymphocytes. J Immunol 1998; 161:138-47.
45. Stout RD, Suttles J. Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev 2005; 205:60-71.
46. Yang HC, Lin CH, Hsu CL, et al. A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. J Biomed Sci 2006 (in press).