Viral Replication in the Nasopharynx Is Associated with Diarrhea in Patients with Severe Acute Respiratory Syndrome

Clinical Infectious Diseases

Volumn 38, Issue 4, 2004, Pages 467-475

  Cheng, V C C ^a   Hung, I F N ^a   Tang, B S F ^a   Chu, C M ^b   Wong, M M L ^c   Chan, K H ^a   Wu, A K L ^d   Tse, D M W ^c   Chan, K S ^b   Zheng, B J ^a   Peiris, J S M ^a   Sung, J J Y ^d   Yuen, K Y ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNITED CHRISTIAN HOSPITAL   (Hong Kong)

^c Caritas Medical Centre Hong Kong   (Hong Kong)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AZITHROMYCIN; CORTICOSTEROID; HYDROCORTISONE; LAMIVUDINE; LEVOFLOXACIN; METHYLPREDNISOLONE; PREDNISOLONE; RIBAVIRIN;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CHEMICAL ANALYSIS; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DIARRHEA; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; ENTERIC VIRUS; FEMALE; GASTROINTESTINAL TRACT; HUMAN; LUNG; MAJOR CLINICAL STUDY; MALE; MICROBIOLOGICAL EXAMINATION; MORTALITY; NASOPHARYNX; PATHOGENESIS; PATIENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIODIAGNOSIS; RETROSPECTIVE STUDY; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SYMPTOM; VIRUS LOAD; VIRUS REPLICATION;

ADULT; AGED; AGED, 80 AND OVER; DIARRHEA; DISEASE OUTBREAKS; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNX; RETROSPECTIVE STUDIES; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS REPLICATION;

EID: 10744223862     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/382681     Document Type: Article

References (50)

1. World Health Organization. Summary table of SARS cases by country, 1 November 2002-7 August 2003. 23 September 2003. Available at: http://www.who.int/csr/sars/country/en/country2003_08_15.pdf. Accessed 2 October 2003.
2. Ksiazek TG, Erdman D, Goldsmith CS, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003; 348:1953-66.
3. Drosten C, Gunther S, Preiser W, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003; 348:1967-76.
4. Peiris JS, Lai ST, Poon LL, et al. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 2003; 361:1319-25.
5. Fouchier RA, Kuiken T, Schutten M, et al. Aetiology: Koch's postulates fulfilled for SARS virus. Nature 2003; 423:240.
6. Kuiken T, Fouchier RA, Schutten M, et al. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet 2003; 362:263-70.
7. Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 2003; 361:1767-72.
8. Chan KH, Poon LLM, Cheng VCC, et al. Detection of SARS coronavirus (SCoV) by RT-PCR, culture, and serology in patients with acute respiratory syndrome (SARS). Emerg Infect Dis (in press).
9. Leung WK, To KF, Chan PK, et al. Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection. Gastroenterology 2003; 125:1011-7.
10. Zheng BJ, Chang RX, Ma GZ, et al. Rotavirus infection of the oropharynx and respiratory tract in young children. J Med Virol 1991; 34:29-37.
11. Fragoso M, Kumar A, Murray DL. Rotavirus in nasopharyngeal secretions of children with upper respiratory tract infections. Diagn Microbiol Infect Dis 1986; 4:87-8.
12. Lee N, Hui D, Wu A, et al. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 2003; 348:1986-94.
13. Li SS, Cheng CW, Fu CL et al. Left ventricular performance in patients with severe acute respiratory syndrome: a 30-day echocardiogram follow-up study. Circulation 2003; 108:1798-803.
14. Wang JL, Wang JT, Yu CJ, et al. Rhabdomyolysis associated with probable SARS. Am J Med 2003; 115:421-2.
15. Chan JW, Ng CK, Chan YH, et al. Short term outcome and risk factors for adverse clinical outcomes in adults with severe acute respiratory syndrome (SARS). Thorax 2003; 58:686-9.
16. Zhao Z, Zhang F, Xu M, et al. Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol 2003; 52:715-20.
17. Hsu LY, Lee CC, Green JA, et al. Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts. Emerg Infect Dis 2003; 9:713-7.
18. Booth CM, Matukas LM, Tomlinson GA, et al. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 2003; 289:2801-9.
19. Sopena N, Sabria-Leal M, Pedro-Botet ML, et al. Comparative study of the clinical presentation of Legionella pneumonia and other community-acquired pneumonias. Chest 1998; 113:1195-200.
20. Newton JA Jr, Weiss PJ, Litynski JJ. Diarrhea in Pneumocystis carinii pneumonia. Am J Gastroenterol 1993; 88:1138-9.
21. Wang YH, Huang YC, Chang LY, et al. Clinical characteristics of children with influenza A virus infection requiring hospitalization. J Microbiol Immunol Infect 2003; 36:111-6.
22. Pancharoen C, Mekmullica J, Thisyakorn U. Primary dengue infection: what are the clinical distinctions from secondary infection? Southeast Asian J Trop Med Public Health 2001; 32:476-80.
23. Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW. Treatment of SARS with human interferons. Lancet 2003; 362:293-4.
24. Martina BE, Haagmans BL, Kuiken T, et al. Virology: SARS virus infection of cats and ferrets. Nature 2003; 425:915.
25. Nicholls JM, Poon LL, Lee KC, et al. Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003; 361:1773-8.
26. Brouard J, Freymuth F, Vabret A, Jokic M, Guillois B, Duhamel JF. Viral co-infections in immunocompetent infants with bronchiolitis: prospective epidemiologic study. Arch Pediatr 2000; 7(Suppl 3): 531s-5s.
27. Nuovo GJ, Owor G, Andrew T, Magro C. Histologic distribution of fatal rotaviral pneumonitis: an immunohistochemical and RT in situ PCR analysis. Diagn Mol Pathol 2002; 11:140-5.
28. Yolken RH, Lawrence F, Leister F, Takiff HE, Strauss SE. Gastroenteritis associated with enteric type adenovirus in hospitalized infants. J Pediatr 1982; 101:21-6.
29. Brandt CD, Kim HW, Rodriguez WJ, Arrobio JO, Jeffries BC, Parrott RH. Simultaneous infections with different enteric and respiratory tract viruses. J Clin Microbiol 1986; 23:177-9.
30. Resta S, Luby JP, Rosenfeld CR, Siegel JD. Isolation and propagation of a human enteric coronavirus. Science 1985; 229:978-81.
31. Gerna G, Passarani N, Battaglia M, Rondanelli EG. Human enteric coronaviruses: antigenic relatedness to human coronavirus OC43 and possible etiologic role in viral gastroenteritis. J Infect Dis 1985; 151: 796-803.
32. Cavallaro JJ, Monto AS. Community-wide outbreak of infection with a 229E-like coronavirus in Tecumseh, Michigan. J Infect Dis 1970; 122: 272-9.
33. Falsey AR, Walsh EE, Hayden FG. Rhinovirus and coronavirus infection-associated hospitalizations among older adults. J Infect Dis 2002; 185:1338-41.
34. Vabret A, Mourez T, Gouarin S, Petitjean J, Freymuth F. An outbreak of coronavirus OC43 respiratory infection in Normandy, France. Clin Infect Dis 2003; 36:985-9.
35. Zhang XM, Herbst W, Kousoulas KG, Storz J. Biological and genetic characterization of a hemagglutinating coronavirus isolated from a diarrhoeic child. J Med Virol 1994; 44:152-61.
36. Clark MA. Bovine coronavirus. Br Vet J 1993; 149:51-70.
37. Laude H, Van Reeth K, Pensaert M. Porcine respiratory coronavirus: molecular features and virus-host interactions. Vet Res 1993; 24:125-50.
38. Gelinas AM, Boutin M, Sasseville AM, Dea S. Bovine coronaviruses associated with enteric and respiratory diseases in Canadian dairy cattle display different reactivities to anti-HE monoclonal antibodies and distinct amino acid changes in their HE, S and ns4.9 protein. Virus Res 2001; 76:43-57.
39. Tsunemitsu H, el-Kanawati ZR, Smith DR, Reed HH, Saif LJ. Isolation of coronaviruses antigenically indistinguishable from bovine coronavirus from wild ruminants with diarrhea. J Clin Microbiol 1995; 33: 3264-9.
40. Mochizuki M, Osawa N, Ishida T. Feline coronavirus participation in diarrhea of cats. J Vet Med Sci 1999; 61:1071-3.
41. Cho KO, Halbur PG, Bruna JD, et al. Detection and isolation of coronavirus from feces of three herds of feedlot cattle during outbreaks of winter dysentery-like disease. J Am Vet Med Assoc 2000; 217:1191-4.
42. Williams BH, Kiupel M, West KH, Raymond JT, Grant CK, Glickman LT. Coronavirus-associated epizootic catarrhal enteritis in ferrets. J Am Vet Med Assoc 2000; 217:526-30.
43. Wunschmann A, Frank R, Pomeroy K, Kapil S. Enteric coronavirus infection in a juvenile dromedary (Camelus dromedarius). J Vet Diagn Invest 2002; 14:441-4.
44. Ignjatovic J, Sapats S. Avian infectious bronchitis virus. Rev Sci Tech 2000; 19:493-508.
45. El-Sahly HM, Atmar RL, Glezen WP, Greenberg SB. Spectrum of clinical illness in hospitalized patients with "common cold" virus infections. Clin Infect Dis 2000; 31:96-100.
46. Heikkinen T, Jarvinen A. The common cold. Lancet 2003; 361:51-9.
47. Ballesteros ML, Sanchez CM, Enjuanes L. Two amino acid changes at the N-terminus of transmissible gastroenteritis coronavirus spike protein result in the loss of enteric tropism. Virology 1997; 227:378-88.
48. Sanchez CM, Izeta A, Sanchez-Morgado JM, et al. Targeted recombination demonstrates that the spike gene of transmissible gastroenteritis coronavirus is a determinant of its enteric tropism and virulence. J Virol 1999; 73:7607-18.
49. Guan Y, Peiris JS, Zheng B, et al. Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. Lancet 2004; 363:88104.
50. Koci MD, Moser LA, Kelley LA, Larsen D, Brown CC, Schultz-Cherry S. Astrovirus induces diarrhea in the absence of inflammation and cell death. J Virol 2003; 77:11798-808.