Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death

Biochemical and Biophysical Research Communications

Volumn 290, Issue 4, 2002, Pages 1275-1281

  Araki, Takashi ^a   Hayashi, Matsuhiko ^a   Watanabe, Naohide ^a   Yoshino, Jun ^a   Saruta, Takao ^a   Kanuka, Hirotaka ^b   Miura, Masayuki ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

4,4 diisothiocyanatostilbene 2,2 dislufonic acid (DIDS); Apoptosis; AVD; Mcl 1; PI 3 kinase; Staurosporine

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; GENE PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROPIDIUM IODIDE; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN BIK; PROTEIN KINASE B; PROTEIN MCL 1; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA STRUCTURE; DOWN REGULATION; EPITHELIUM CELL; KIDNEY EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 0036289544     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6329     Document Type: Article

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