The tyrosine kinase p56(lck) mediates activation of swelling-induced chloride channels in lymphocytes

Journal of Cell Biology

Volumn 141, Issue 1, 1998, Pages 281-286

  Lepple Wienhues, Albrecht ^a   Szabò, Ildikò ^a   Laun, Tilmann ^a   Kaba, Nubia Kristen ^a   Gulbins, Erich ^a   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; HERBIMYCIN A; PROTEIN TYROSINE KINASE; BENZOQUINONE DERIVATIVE; ENZYME INHIBITOR; HERBIMYCIN; HYPOTONIC SOLUTION; MACROCYCLIC LACTAM; PHENOL DERIVATIVE; PROTEIN KINASE LCK; QUINONE DERIVATIVE; RECOMBINANT PROTEIN;

ARTICLE; CELL SWELLING; CHANNEL GATING; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; OSMOREGULATION; OSMOSIS; PATCH CLAMP; PRIORITY JOURNAL; SLOW INWARD CURRENT; T LYMPHOCYTE; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; PHYSIOLOGY;

BENZOQUINONES; CELL LINE; CHLORIDE CHANNELS; ENZYME INHIBITORS; HUMANS; HYPOTONIC SOLUTIONS; JURKAT CELLS; LACTAMS, MACROCYCLIC; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PHENOLS; QUINONES; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0032489679     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.141.1.281     Document Type: Article

References (28)

1. August, A., and B. Dupont. 1995. Activation of extracellular signal-regulated protein kinase (ERK/MAP kinase) following CD28 cross-linking: activation in cells lacking p56lck. Tissue Antigens. 46:155-162.
2. Cahalan M.D., and R.S. Lewis. 1988. Role of potassium and chloride channels in volume regulation by T lymphocytes. In Cell Physiology of Blood. R.B. Gunn, and J.C. Parker, editors. Rockefeller University Press, New York. 281-301.
3. Deutsch, C., and S.C. Lee. 1988. Cell volume regulation in lymphocytes. Renal Physiol. Biochem. 3:260-276.
4. Doroshenko, P., and E. Neher. 1992. Volume-sensitive chloride conductance in bovine chromaffin cell membrane. J. Physiol. (Lond.). 449:197-218.
5. Fischer, H., and T.E. Machen. 1996. The tyrosine kinase p60c-src regulates the fast gate of the cystic fibrosis transmembrane conductance regulator chloride channel. Biophys. J. 71:3073-3082.
6. Gabriel, S.E., L.L. Clarke, R.C. Boucher, and M.J. Stutts. 1993. CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship. Nature. 363:263-268.
7. Garber, S. 1992. Outwardly rectifying chloride channels in lymphocytes. J. Membr. Biol. 127:49-56.
8. Gill, D.R., S.C. Hyde, C.F. Higgins, M.A. Valverde, G.M. Mintenig, and F.V. Sepulveda. 1992. Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell. 71:23-32.
9. Jackson, P.S., and K. Strange. 1995. Single-channel properties of a volume-sensitive anion conductance. Current activation occurs by abrupt switching of closed channels to an open state. J. Gen. Physiol. 105:643-660.
10. Jackson, P.S., R. Morrison, and K. Strange. 1994. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding. Am. J. Physiol. 267:1203-1209.
11. - and ATP. Am. J. Physiol. 270:57-66.
12. Kunzelman, K., H. Pavenstädt, and R. Greger. 1989. Properties and regulations of chloride channels in cystic fibrosis and normal airway cells. Pflügers. Arch. 415:172-182.
13. Lang, F., G. Busch, M. Ritter, H. Völkl, S. Waldegger, E. Gulbins, and D. Häusinger. 1998. The functional significance of cell volume regulation mechanisms. Physiol. Rev. 78:247-306.
14. - current by f-actin. J. Membr. Biol. 147:283-294.
15. Lewis, R.S., and M.D. Cahalan. 1988. Subset-specific expression of potassium channels in developing murine T lymphocytes. Science 239:771-775.
16. Lewis, R.S., P.E. Ross, and M.D. Cahalan. 1993. Chloride channels activated by osmotic stress in T lymphocytes. J. Gen. Physiol. 101:801-826.
17. Meyer, K., and C. Korbmacher. 1996. Cell swelling activates ATP-dependent voltage-gated chloride channels in M-1 mouse cortical collecting duct cells. J. Gen. Physiol. 108:177-193.
18. - channels by multifunctional CaM kinase. Neuron. 6:547-555.
19. - channels in human epithelial cells. Jpn. J. Physiol. 44(Suppl.): 77-79.
20. 2+ influx pathways mediated by swelling or stores depletion in mouse thymocytes. J. Gen. Physiol. 106:415-444.
21. Ross, P.R., S.S. Garber, and M.D. Cahalan. 1994. Membrane chloride conductance and capacitance in Jurkat T lymphocytes during osmotic swelling. Biophys. J. 66:169-178.
22. Schliess, F., R. Sinning, R. Fischer, C. Schmalenbach, and D. Haussinger. 1996. Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling. Biochem. J. 320:167-171.
23. Schwiebert, E.M., M.E. Egan, T.H. Hwang, S.B. Fulmer, S.S. Allen, G.R. Cutting, and W.B. Guggino. 1995. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell. 81:1063-1073.
24. - channels in normal and cystic fibrosis epithelial cells. Am. J. Physiol. 261:658-674.
25. Sorota, S. 1992. Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method. Circ. Res. 70:679-687.
26. Sorota, S. 1995. Tyrosine protein kinase inhibitors prevent activation of cardiac swelling-induced chloride current. Pflugers Arch. 431:178-185.
27. Tilly, B.C., N. van den Berghe, L.G. Tertoolen, M.J. Edixhoven, and H.R. de Jonge. 1993. Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances. J. Biol. Chem. 268:19919-19922.
28. Voets, T., V. Manolopoulos, J. Eggermont, C. Ellory, G. Droogmans, and B. Nilius. 1998. Regulation of a swelling-activated chloride current in bovine endothelium by protein tyrosine phosphorylation and G proteins. J. Physiol. 506:341-352.