Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 3, 2006, Pages 246-252

  Clemente, José C ^a   Govindasamy, Lakshmanan ^a   Madabushi, Amrita ^a   Fisher, S Zoë ^a   Moose, Rebecca E ^a   Yowell, Charles A ^b   Hidaka, Koushi ^c   Kimura, Tooru ^c   Hayashi, Yoshio ^c   Kiso, Yoshiaki ^c   Agbandje Mckenna, Mavis ^a   Dame, John B ^b   Dunn, Ben M ^a   McKenna, Robert ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE;

3 AMINO 2 HYDROXY 4 PHENYLBUTYRIC ACID; 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID; ANTIMALARIAL AGENT; ARYLBUTYRIC ACID DERIVATIVE; ASPARTIC PROTEINASE; PLASMEPSIN; PROTEINASE INHIBITOR;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CRYSTALLIZATION; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PLASMODIUM MALARIAE; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIMALARIALS; ASPARTIC ENDOPEPTIDASES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHENYLBUTYRATES; PLASMODIUM MALARIAE; PROTEASE INHIBITORS; PROTEIN BINDING;

EID: 33646573016     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444905041260     Document Type: Article

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