Impact of benzo[a]pyrene-2′-deoxyguanosine lesions on methylation of DNA by SssI and HhaI DNA methyltransferases

Biochemistry

Volumn 45, Issue 19, 2006, Pages 6142-6159

  Subach, Oksana M ^a   Baskunov, Vladimir B ^a   Darii, Maria V ^a   Maltseva, Diana V ^a   Alexandrov, Dmitrii A ^a   Kirsanova, Olga V ^a,d   Kolbanovskiy, Alexander ^b   Kolbanovskiy, Marina ^b   Johnson, Francis ^c   Bonala, Radha ^c   Geacintov, Nicholas E ^b   Gromova, Elizaveta S ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b NEW YORK UNIVERSITY   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBONS; DNA; GENETIC ENGINEERING; PERTURBATION TECHNIQUES;

GREATER ADVERSE IMPACTS; HEMIMETHYLATED DUPLEXES; METHYLATION; POTENTIAL EPIGENETIC MECHANISMS;

PROTEINS;

BENZO[A]PYRENE; BENZO[A]PYRENE 2' DEOXYGUANOSINE; CARBON; CARCINOGEN; CYTOSINE; DEOXYCYTIDINE; DEOXYGUANOSINE DERIVATIVE; DINUCLEOTIDE; DNA; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE HHAI; DNA METHYLTRANSFERASE SSSI; GUANINE; METHYL GROUP; OLIGODEOXYNUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL CARCINOGENESIS; CHEMICAL STRUCTURE; CONFORMATION; CPG ISLAND; DNA BINDING; DNA DAMAGE; DNA METHYLATION; DNA MODIFICATION; ENZYME ACTIVE SITE; EPIGENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROKARYOTE; PROTEIN DNA BINDING; STEREOISOMERISM; STRUCTURE ANALYSIS;

BASE SEQUENCE; BENZO(A)PYRENE; DEOXYGUANOSINE; DNA DAMAGE; DNA METHYLATION; DNA PRIMERS; FLUORESCENCE POLARIZATION; KINETICS; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC); SUBSTRATE SPECIFICITY;

PROKARYOTA;

EID: 33646560367     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0511639     Document Type: Article

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