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Volumn 1758, Issue 1, 2006, Pages 45-54

Rabbit small intestine does not contain an annexin II/caveolin 1 complex as a target for 2-azetidinone cholesterol absorption inhibitors

Author keywords

Annexin II caveolin1; Brush border membrane (rabbit); Cholesterol absorption; Ezetimibe; Photoaffinity labelling

Indexed keywords

2 AZETIDINONE DERIVATIVE; ANTIBODY; AVE 5530; CAVEOLIN 1; CHOLESTEROL; CHOLESTEROL ABSORPTION INHIBITOR; EZETIMIBE; HYPOCHOLESTEROLEMIC AGENT; LIPOCORTIN 2; UNCLASSIFIED DRUG;

EID: 33646447507     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2005.12.007     Document Type: Article
Times cited : (9)

References (33)
  • 1
    • 0027411589 scopus 로고
    • Pharmacological consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside)
    • Harwood Jr. H.J., Chandler C.E., Pellarin L.D., Bangerter F.W., Wilkins R.W., Long C.A., Cosgrove P.G., Malinow M.R., Marzetta C.A., Pettini J.L., Savoy Y.E., and Mayne J.T. Pharmacological consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside). J. Lipid Res. 34 (1993) 377-395
    • (1993) J. Lipid Res. , vol.34 , pp. 377-395
    • Harwood Jr., H.J.1    Chandler, C.E.2    Pellarin, L.D.3    Bangerter, F.W.4    Wilkins, R.W.5    Long, C.A.6    Cosgrove, P.G.7    Malinow, M.R.8    Marzetta, C.A.9    Pettini, J.L.10    Savoy, Y.E.11    Mayne, J.T.12
  • 3
    • 0014791296 scopus 로고
    • Metabolism of β-sitosterol in man
    • Salen G., Ahrens E., and Grundy S. Metabolism of β-sitosterol in man. J. Clin. Invest. 49 (1970) 952-967
    • (1970) J. Clin. Invest. , vol.49 , pp. 952-967
    • Salen, G.1    Ahrens, E.2    Grundy, S.3
  • 4
    • 0032861789 scopus 로고    scopus 로고
    • Intestinal cholesterol absorption
    • Dawson P.A., and Rudel L.L. Intestinal cholesterol absorption. Curr. Opin. Lipidol. 10 (1999) 315-320
    • (1999) Curr. Opin. Lipidol. , vol.10 , pp. 315-320
    • Dawson, P.A.1    Rudel, L.L.2
  • 6
    • 0027434874 scopus 로고
    • Cholesterol transport function of pancreatic cholesterol esterase: directed sterol uptake and esterification in enterocytes
    • Lopez-Candale S.A., Bosner M.S., Spilburg C.A., and Lange L.G. Cholesterol transport function of pancreatic cholesterol esterase: directed sterol uptake and esterification in enterocytes. Biochemistry 32 (1993) 12085-12089
    • (1993) Biochemistry , vol.32 , pp. 12085-12089
    • Lopez-Candale, S.A.1    Bosner, M.S.2    Spilburg, C.A.3    Lange, L.G.4
  • 10
    • 0034003105 scopus 로고    scopus 로고
    • Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and ist glucuronide, SCH60663
    • Van Heek M., Farley C., Compton D.S., Hoos L., Alton K.B., Sybertz E.J., and Davis Jr. H.R. Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and ist glucuronide, SCH60663. Br. J. Pharmacol. 129 (2000) 1748-1754
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 1748-1754
    • Van Heek, M.1    Farley, C.2    Compton, D.S.3    Hoos, L.4    Alton, K.B.5    Sybertz, E.J.6    Davis Jr., H.R.7
  • 11
    • 0034731470 scopus 로고    scopus 로고
    • Identification of binding proteins for cholesterol absorption inhibitors as components of the intestinal cholesterol transporter
    • Kramer W., Glombik H., Petry S., Heuer H., Schäfer H.L., Wendler W., Corsiero D., Girbig F., and Weyland C. Identification of binding proteins for cholesterol absorption inhibitors as components of the intestinal cholesterol transporter. FEBS Lett. 487 (2000) 293-297
    • (2000) FEBS Lett. , vol.487 , pp. 293-297
    • Kramer, W.1    Glombik, H.2    Petry, S.3    Heuer, H.4    Schäfer, H.L.5    Wendler, W.6    Corsiero, D.7    Girbig, F.8    Weyland, C.9
  • 12
    • 33646459414 scopus 로고    scopus 로고
    • W. Kramer, H. Glombik, Protein extracted from the intestines of vertebrates, which absorbs cholesterol, and the use of this protein for identifiying inhibitors of intestinal cholesterol transport. International Patent Application WO 02/18432 (2000).
  • 13
    • 0037377528 scopus 로고    scopus 로고
    • Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors
    • Frick W., Bauer-Schäfer A., Girbig F., Corsiero D., Heuer H., and Kramer W. Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors. Bioorg. Med. Chem. 11 (2003) 1639-1642
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 1639-1642
    • Frick, W.1    Bauer-Schäfer, A.2    Girbig, F.3    Corsiero, D.4    Heuer, H.5    Kramer, W.6
  • 14
    • 0033792318 scopus 로고    scopus 로고
    • Cholesterol binds to synaptophysin and is required for biosynthesis of synaptic vesicles
    • Thiele C., Hannah M.J., Fahrenholz F., and Huttner W.B. Cholesterol binds to synaptophysin and is required for biosynthesis of synaptic vesicles. Nat. Cell Biol. 2 (2000) 42-49
    • (2000) Nat. Cell Biol. , vol.2 , pp. 42-49
    • Thiele, C.1    Hannah, M.J.2    Fahrenholz, F.3    Huttner, W.B.4
  • 16
    • 0037783980 scopus 로고    scopus 로고
    • Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane
    • Kramer W., Girbig F., Corsiero D., Burger K., Fahrenholz F., Jung C., and Müller G. Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocyte brush border membrane. Biochim. Biophys. Acta 1633 (2003) 13-26
    • (2003) Biochim. Biophys. Acta , vol.1633 , pp. 13-26
    • Kramer, W.1    Girbig, F.2    Corsiero, D.3    Burger, K.4    Fahrenholz, F.5    Jung, C.6    Müller, G.7
  • 20
    • 16844376244 scopus 로고    scopus 로고
    • Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia
    • Davies J.P., Scott C., Oishi K., Liapis A., and Ioannou Y.A. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. J. Biol. Chem. 280 (2005) 2710-2720
    • (2005) J. Biol. Chem. , vol.280 , pp. 2710-2720
    • Davies, J.P.1    Scott, C.2    Oishi, K.3    Liapis, A.4    Ioannou, Y.A.5
  • 21
    • 1542618335 scopus 로고    scopus 로고
    • Annexin 2-caveolin 1 complex is a target of ezetimibe and regulates intestinal cholesterol transport
    • Smart E.J., De Rose R.A., and Farber S.A. Annexin 2-caveolin 1 complex is a target of ezetimibe and regulates intestinal cholesterol transport. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 3450-3455
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 3450-3455
    • Smart, E.J.1    De Rose, R.A.2    Farber, S.A.3
  • 22
    • 33646454806 scopus 로고    scopus 로고
    • H. Glombik, W. Kramer, S. Flohr, W. Frick, H. Heuer, G. Jaehne, A. Lindenschmidt, H.L. Schaefer, Novel 1,2-diphenylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism. PCT Int. Patent Appl. WO 02/50027 (2002).
  • 23
    • 0027250469 scopus 로고
    • +-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93 kDa and a peripheral 14 kDa bile acid-binding membrane protein along the duodenum-ileum axis
    • +-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93 kDa and a peripheral 14 kDa bile acid-binding membrane protein along the duodenum-ileum axis. J. Biol. Chem. 268 (1993) 18035-18046
    • (1993) J. Biol. Chem. , vol.268 , pp. 18035-18046
    • Kramer, W.1    Girbig, F.2    Gutjahr, U.3    Kowalewski, S.4    Jouvenal, K.5    Müller, G.6    Tripier, D.7    Wess, G.8
  • 26
    • 0037089350 scopus 로고    scopus 로고
    • Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine
    • Cai T.Q., Guo Q., Wong B., Milot D., Zhang L., and Wright S.D. Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine. Biochim. Biophys. Acta 1581 (2002) 100-108
    • (2002) Biochim. Biophys. Acta , vol.1581 , pp. 100-108
    • Cai, T.Q.1    Guo, Q.2    Wong, B.3    Milot, D.4    Zhang, L.5    Wright, S.D.6
  • 27
    • 0031706594 scopus 로고    scopus 로고
    • Caveolin is present in intestinal cells: role in cholesterol trafficking?
    • Field F.J., Born E., Murthy S., and Mathur S.N. Caveolin is present in intestinal cells: role in cholesterol trafficking?. J. Lipid Res. 39 (1998) 1938-1950
    • (1998) J. Lipid Res. , vol.39 , pp. 1938-1950
    • Field, F.J.1    Born, E.2    Murthy, S.3    Mathur, S.N.4
  • 28
    • 0036083696 scopus 로고    scopus 로고
    • Annexins: from structure to function
    • Gerke V., and Moss S.E. Annexins: from structure to function. Physiol. Rev. 82 (2002) 331-371
    • (2002) Physiol. Rev. , vol.82 , pp. 331-371
    • Gerke, V.1    Moss, S.E.2
  • 29
    • 0027426724 scopus 로고
    • The subcellular distribution of early endosomes is affected by the annexin II 2p11 (2) complex
    • Harder T., and Gerke V. The subcellular distribution of early endosomes is affected by the annexin II 2p11 (2) complex. J. Cell Biol. 123 (1993) 1119-1132
    • (1993) J. Cell Biol. , vol.123 , pp. 1119-1132
    • Harder, T.1    Gerke, V.2
  • 31
    • 0026063254 scopus 로고
    • The participation of annexin II (calpactin I) in calcium-evoked exocytosis requires protein kinase C
    • Sarafian T., Pradel L.A., Henry J.P., Annis D., and Bader M.F. The participation of annexin II (calpactin I) in calcium-evoked exocytosis requires protein kinase C. J. Cell Biol. 114 (1991) 1135-1147
    • (1991) J. Cell Biol. , vol.114 , pp. 1135-1147
    • Sarafian, T.1    Pradel, L.A.2    Henry, J.P.3    Annis, D.4    Bader, M.F.5
  • 32
    • 0037926403 scopus 로고    scopus 로고
    • Annexin II regulates multivescular endosome biogenesis in the degradation pathway of animal cells
    • Mayran N., Parton R.G., and Grueneberg J. Annexin II regulates multivescular endosome biogenesis in the degradation pathway of animal cells. EMBO J. 22 (2003) 2353-3242
    • (2003) EMBO J. , vol.22 , pp. 2353-3242
    • Mayran, N.1    Parton, R.G.2    Grueneberg, J.3
  • 33
    • 23044498557 scopus 로고    scopus 로고
    • Caveolin-1 is not required for murine intestinal cholesterol transport
    • Valasek M.A., Weng J., Shaul P.W., Anderson R.G., and Repa J.J. Caveolin-1 is not required for murine intestinal cholesterol transport. J. Biol. Chem. 280 (2005) 28103-28109
    • (2005) J. Biol. Chem. , vol.280 , pp. 28103-28109
    • Valasek, M.A.1    Weng, J.2    Shaul, P.W.3    Anderson, R.G.4    Repa, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.