Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 8, 2003, Pages 1639-1642

  Frick, Wendelin ^a   Bauer Schäfer, Andrea ^a   Bauer, Jochen ^a   Girbig, Frank ^a   Corsiero, Daniel ^a   Heuer, Hubert ^a   Kramer, Werner ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 AZETIDINONE DERIVATIVE; 5 (2 OXOHEXAHYDROTHIENO[3,4 D]IMIDAZOL 6 YL)PENTANOIC ACID[2 (4 AZIDOPHENYL) 1 [4 [4 [3 (3 HYDROXY 3 PHENYLPROPYL) 2 (4 METHYOXYPHENYL) 4 OXOAZETIDIN 1 YL]PHENYLCARBAMOYL]BUTYLCARBAMOYL]ETHYL]AMIDE; BIOTIN; CHOLESTEROL; EZETIMIBE; STREPTAVIDIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER MEMBRANE; MEMBRANE VESICLE; MOUSE; NONHUMAN; PHOTOAFFINITY LABELING; PHOTOREACTIVITY; SYNTHESIS; TISSUE DISTRIBUTION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AZETIDINES; BIOTIN; CARBON RADIOISOTOPES; CHOLESTEROL; DRUG DESIGN; FECES; ILEUM; LIVER; MEMBRANE PROTEINS; MICE; MICROVILLI; PHOTOAFFINITY LABELS; RABBITS; RATS;

EID: 0037377528     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00047-6     Document Type: Article

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