Volatile anaesthetics depolarize neural mitochondria by inhibiton of the electron transport chain

Acta Anaesthesiologica Scandinavica

Volumn 50, Issue 5, 2006, Pages 572-579

  Bains, R ^a   Moe, M C ^a   Larsen, G A ^a   Berg Johnsen, J ^a   Vinje, M L ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

CNS; Electron transport chain; Isoflurane; Mitochondrial membrane potential; Sevoflurane; Synaptosomes; Volatile anesthetics

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYTOCHROME C OXIDASE; FLUORESCENT DYE; FURA 2; INHALATION ANESTHETIC AGENT; ISOFLURANE; JC 1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SEVOFLURANE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; ENZYME INHIBITION; FEMALE; MEMBRANE DEPOLARIZATION; METABOLIC INHIBITION; MINIMUM LUNG ALVEOLUS CONCENTRATION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SYNAPTOSOME;

ADENOSINE TRIPHOSPHATE; ANESTHETICS, INHALATION; ANIMALS; CALCIUM; ELECTRON TRANSPORT; FLUORESCENT DYES; ISOFLURANE; METHYL ETHERS; MICROSCOPY, ELECTRON; MITOCHONDRIA; PRESYNAPTIC TERMINALS; PULMONARY ALVEOLI; RATS; SYNAPTOSOMES;

EID: 33646259509     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2006.00988.x     Document Type: Article

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