Differing molecular mechanisms appear to underlie early toxicity of prefibrillar HypF-N aggregates to different cell types

FEBS Journal

Volumn 273, Issue 10, 2006, Pages 2206-2222

  Cecchi, Cristina ^a   Pensalfini, Anna ^a   Baglioni, Serena ^a   Fiorillo, Claudia ^a   Caporale, Roberto ^b   Formigli, Lucia ^a   Liguri, Gianfranco ^a   Stefani, Massimo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Amyloid toxicity; Apoptosis; Mitochondrial permeability transition pore opening; Prefibrillar protein aggregates; Protein misfolding and cell death

Indexed keywords

AMYLOID PROTEIN; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 8; CASPASE 9; CHOLESTEROL; CYTOCHROME C; DNA FRAGMENT; N TERMINAL DOMAIN OF THE PROKARYOTIC HYDROGENASE MATURATION FACTOR HYPF; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL LINE; CELL MEMBRANE; CELL VIABILITY; CHANNEL GATING; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CALCIUM; CASPASE 8; CASPASE 9; CASPASES; CELL MEMBRANE; CHOLESTEROL; ENDOTHELIAL CELLS; FIBROBLASTS; HUMANS; MICE; OXIDATION-REDUCTION; TIME FACTORS;

ANIMALIA; MURINAE; PROKARYOTA;

EID: 33646240364     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05234.x     Document Type: Article

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