Inhibition by endomorphin-1 and endomorphin-2 of excitatory transmission in adult rat substantia gelatinosa neurons

Neuroscience

Volumn 139, Issue 3, 2006, Pages 1095-1105

  Fujita, T ^a   Kumamoto, E ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

opioid receptor; endomorphin; hyperpolarization; pain; patch clamp; spinal dorsal horn

Indexed keywords

4 AMINOPYRIDINE; BARIUM ION; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLARGINYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIPROTIN A; ENDOMORPHIN 1; ENDOMORPHIN 2; MU OPIATE RECEPTOR ANTAGONIST; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EXCITATORY POSTSYNAPTIC POTENTIAL; INHIBITORY POSTSYNAPTIC POTENTIAL; ION CONDUCTANCE; MALE; NEUROTRANSMISSION; NONHUMAN; PATCH CLAMP; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SUBSTANTIA GELATINOSA;

ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; EXCITATORY POSTSYNAPTIC POTENTIALS; NEUROTRANSMITTER AGENTS; OLIGOPEPTIDES; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, OPIOID, MU; SUBSTANTIA GELATINOSA; SYNAPTIC TRANSMISSION;

EID: 33646124954     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.01.010     Document Type: Article

References (53)

1. Aimone L.D., and Yaksh T.L. Opioid modulation of capsaicin-evoked release of substance P from rat spinal cord in vivo. Peptides 10 (1989) 1127-1131
2. Besse D., Lombard M.C., Zajac J.M., Roques B.P., and Besson J.M. Pre- and postsynaptic distribution of μ, δ and κ opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord. Brain Res 521 (1990) 15-22
3. Chapman V., Diaz A., and Dickenson A.H. Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-2 on evoked dorsal horn neuronal responses in the rat. Br J Pharmacol 122 (1997) 1537-1539
4. Fujita T., Yang K., Kawasaki Y., and Kumamoto E. Effects of endomorphins on excitatory transmission in substantia gelatinosa neurons of the adult rat spinal cord. Jpn J Physiol 53 (2003) S228
5. Fürst S. Transmitters involved in antinociception in the spinal cord. Brain Res Bull 48 (1999) 129-141
6. Goldberg I.E., Rossi G.C., Letchworth S.R., Mathis J.P., Ryan-Moro J., Leventhal L., Su W., Emmel D., Bolan E.A., and Pasternak G.W. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther 286 (1998) 1007-1013
7. Gong J., Strong J.A., Zhang S., Yue X., DeHaven R.N., Daubert J.D., Cassel J.A., Yu G., Mansson E., and Yu L. Endomorphins fully activate a cloned human mu opioid receptor. FEBS Lett 439 (1998) 152-156
8. Grass S., Xu I.S., Wiesenfeld-Hallin Z., and Xu X.-J. Comparison of the effect of intrathecal endomorphin-1 and endomorphin-2 on spinal cord excitability in rats. Neurosci Lett 324 (2002) 197-200
9. Grudt T.J., and Williams J.T. μ-Opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat. J Neurosci 14 (1994) 1646-1654
10. 2+ channel currents in rodent NG108-15 cells overexpressing μ-opioid receptors. J Physiol 507 (1998) 71-75
11. Horvath G. Endomorphin-1 and endomorphin-2. pharmacology of the selective endogenous μ-opioid receptor agonists. Pharmacol Ther 88 (2000) 437-463
12. Horvath G., Szikszay M., Tömböly C., and Benedek G. Antinociceptive effects of intrathecal endomorphin-1 and -2 in rats. Life Sci 65 (1999) 2635-2641
13. Kato T., Nagatsu T., Kimura T., and Sakakibara S. Studies on substrate specificity of X-prolyl dipeptidyl-aminopeptidase during new chromogenic substrates, X-Y-p-nitroanilides. Experientia 34 (1978) 319-320
14. Koga A., Fujita T., Totoki T., and Kumamoto E. Tramadol produces outward currents by activating μ-opioid receptors in adult rat substantia gelatinosa neurones. Br J Pharmacol 145 (2005) 602-607
15. Kohno T., Kumamoto E., Higashi H., Shimoji K., and Yoshimura M. Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord. J Physiol 518 (1999) 803-813
16. Kramer T.H., Shook J.E., Kazmierski W., Ayres E.A., Wire W.S., Hruby V.J., and Burks T.F. Novel peptidic mu opioid antagonists. pharmacologic characterization in vitro and in vivo. J Pharmacol Exp Ther 249 (1989) 544-551
17. Liu T., Fujita T., Kawasaki Y., and Kumamoto E. Regulation by equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons. Brain Res Bull 64 (2004) 75-83
18. Luo C., Kumamoto E., Furue H., and Yoshimura M. Nociceptin-induced outward current in substantia gelatinosa neurones of the adult rat spinal cord. Neuroscience 108 (2001) 323-330
19. Luo C., Kumamoto E., Furue H., Chen J., and Yoshimura M. Nociceptin inhibits excitatory but not inhibitory transmission to substantia gelatinosa neurones of adult rat spinal cord. Neuroscience 109 (2002) 349-358
20. Martin-Schild S., Gerall A.A., Kastin A.J., and Zadina J.E. Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers. Peptides 19 (1998) 1783-1789
21. Martin-Schild S., Gerall A.A., Kastin A.J., and Zadina J.E. Differential distribution of endomorphin 1- and endomorphin 2-like immunoreactivities in the CNS of the rodent. J Comp Neurol 405 (1999) 450-471
22. Martin-Schild S., Zadina J.E., Gerall A.A., Vigh S., and Kastin A.J. Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord. Peptides 18 (1997) 1641-1649
23. i2α fused to the human mu opioid receptor differently. J Neurochem 81 (2002) 1372-1382
24. 2 opioid binding in the mouse central nervous system. Brain Res 360 (1985) 117-129
25. Narita M., Ozaki S., Ioka M., Mizoguchi H., Nagase H., Tseng L.F., and Suzuki T. Different motivational effects induced by the endogenous μ-opioid receptor ligands endomorphin-1 and -2 in the mouse. Neuroscience 105 (2001) 213-218
26. North R.A., and Williams J.T. On the potassium conductance increased by opioids in rat locus coeruleus neurones. J Physiol 364 (1985) 265-280
27. Ohsawa M., Mizoguchi H., Narita M., Nagase H., Kampine J.P., and Tseng L.F. Differential antinociception induced by spinally administered endomorphin-1 and endomorphin-2 in the mouse. J Pharmacol Exp Ther 298 (2001) 592-597
28. Pasternak G.W., and Wood P.J. Multiple mu opiate receptors. Life Sci 38 (1986) 1889-1898
29. Pierce T.L., Grahek M.D., and Wessendorf M.W. Immunoreactivity for endomorphin-2 occurs in primary afferents in rats and monkey. Neuroreport 9 (1998) 385-389
30. Pohl M., Lombard M.C., Bourgoin S., Carayon A., Benoliel J.J., Mauborgne A., Besson J.M., Hamon M., and Cesselin F. Opioid control of the in vitro release of calcitonin gene-related peptide from primary afferent fibres projecting in the rat cervical cord. Neuropeptides 14 (1989) 151-159
31. Rahman W., Dashwood M.R., Fitzgerald M., Aynsley-Green A., and Dickenson A.H. Postnatal development of multiple opioid receptors in the spinal cord and development of spinal morphine analgesia. Dev Brain Res 108 (1998) 239-254
32. Rónai A.Z., Timár J., Makó E., Erdö F., Gyarmati Z., Tóth G., Orosz G., Fürst S., and Székely J.I. Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV (EC 3.4.14.5) produces naloxone-reversible analgesia in rats. Life Sci 64 (1999) 145-152
33. Sakurada S., Hayashi T., Yuhki M., Fujimura T., Murayama K., Yonezawa A., Sakurada C., Takeshita M., Zadina J.E., Kastin A.J., and Sakurada T. Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone. Brain Res 881 (2000) 1-8
34. Sakurada S., Hayashi T., Yuhki M., Orito T., Zadina J.E., Kastin A.J., Fujimura T., Murayama K., Sakurada C., Sakurada T., Narita M., Suzuki T., Tan-No K., and Tseng L.F. Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse. Eur J Pharmacol 427 (2001) 203-210
35. Sakurada C., Sakurada S., Hayashi T., Katsuyama S., Tan-No K., and Sakurada T. Degradation of endomorphin-2 at the supraspinal level in mice is initiated by dipeptidyl peptidase IV. an in vitro and in vivo study. Biochem Pharmacol 66 (2003) 653-661
36. 2 discriminate different μ-opioid receptor mediated antinociception in mice. Br J Pharmacol 137 (2002) 1143-1146
37. Sakurada S., Zadina J.E., Kastin A.J., Katsuyama S., Fujimura T., Murayama K., Yuki M., Ueda H., and Sakurada T. Differential involvement of μ-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception. Eur J Pharmacol 372 (1999) 25-30
38. Shane R., Wilk S., and Bodnar R.J. Modulation of endomorphin-2-induced analgesia by dipeptidyl peptidase IV. Brain Res 815 (1999) 278-286
39. Stevens C.W., Lacey C.B., Miller K.E., Elde R.P., and Seybold V.S. Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord. Brain Res 550 (1991) 77-85
40. Stone L.S., Fairbanks C.A., Laughlin T.M., Nguyen H.O., Bushy T.M., Wessendorf M.W., and Wilcox G.L. Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2. Neuroreport 8 (1997) 3131-3135
41. Tseng L.F., Narita M., Suganuma C., Mizoguchi H., Ohsawa M., Nagase H., and Kampine J.P. Differential antinociceptive effects of endomorphin-1 and endomorphin-2 in the mouse. J Pharmacol Exp Ther 292 (2000) 576-583
42. Wang Q.-P., Zadina J.E., Guan J.-L., Kastin A.J., Funahashi H., and Shioda S. Endomorphin-2 immunoreactivity in the cervical dorsal horn of the rat spinal cord at the electron microscopic level. Neuroscience 113 (2002) 593-605
43. Wang Q.-P., Zadina J.E., Guan J.-L., and Shioda S. Morphological evidence of endomorphin as an agonist for the mu-opioid receptor in the rat spinal cord. Neurosci Lett 341 (2003) 107-110
44. Williams C.A., Wu S.Y., Dun S.L., Kwok E.H., and Dun N.J. Release of endomorphin-2 like substances from the rat spinal cord. Neurosci Lett 273 (1999) 25-28
45. Willis Jr. W.D., and Coggeshall R.E. Sensory mechanisms of the spinal cord. 2nd edition (1991), Plenum, New York
46. Wu H.-E., MacDougall R.S., Clithero A.D., Leitermann R.J., Terashvili M., and Tseng L.F. Opposite conditioned place preference responses to endomorphin-1 and endomorphin-2 in the mouse. Neurosci Lett 365 (2004) 157-161
47. Wu S.-Y., Dun S.L., Wright M.T., Chang J.-K., and Dun N.J. Endomorphin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons in vitro. Neuroscience 89 (1999) 317-321
48. Wu S.-Y., Ohtubo Y., Brailoiu G.C., and Dun N.J. Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices. Br J Pharmacol 140 (2003) 1088-1096
49. Yajiri Y., and Huang L.-Y.M. Actions of endomorphins on synaptic transmission of Aδ-fibers in spinal cord dorsal horn neurons. J Biomed Sci 7 (2000) 226-231
50. Yang K., Kumamoto E., Furue H., Li Y.-Q., and Yoshimura M. Capsaicin induces a slow inward current which is not mediated by substance P in substantia gelatinosa neurons of the rat spinal cord. Neuropharmacology 39 (2000) 2185-2194
51. Yoshimura M. Slow synaptic transmission in the spinal dorsal horn. In: Kumazawa T., Kruger L., and Mizumura M. (Eds). The polymodal receptor. a gateway to pathological pain, progress in brain research Vol. 113 (1996), Elsevier, Amsterdam 443-462
52. Yoshimura M., and North R.A. Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin. Nature 305 (1983) 529-530
53. Zadina J.E., Hackler L., Ge L.-J., and Kastin A.J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature 386 (1997) 499-502