Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV(EC 3.4.14.5) produces naloxone - Reversible analgesia in rats

Life Sciences

Volumn 64, Issue 2, 1998, Pages 145-152

  Rónai, András Z ^a   Timár, Julianna ^a   Makó, Éva ^a   Erdo, Franciska ^b   Gyarmati, Zsuzsanna ^a   Tóth, Géza ^c   Orosz, György ^d   Fürst, Susanne ^a   Székely, József I ^b  

^a SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^b Institute for Drug Research Budapest   (Hungary)

^c INSTITUTE OF BIOCHEMISTRY   (Hungary)

^d EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Diprotin A; Endomorphins; Guinea pig ileum; Mouse vas deferens; Opioid analgesia; Tyr Pro peptides

Indexed keywords

BRAIN PEPTIDE; DIPEPTIDYL PEPTIDASE IV; DIPROTIN A; ENDOMORPHIN 1; ENDOMORPHIN 2; ENZYME INHIBITOR; MORPHICEPTIN; NALOXONE; NALTREXONE; NORMORPHINE; SODIUM CHLORIDE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG POTENTIATION; GUINEA PIG; ILEUM; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST; VAS DEFERENS;

ANIMALIA; BOVINAE; CAVIA PORCELLUS; SUS SCROFA;

EID: 0032484257     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00544-X     Document Type: Article

References (26)

1. 1. A. HENSCEN, V. BRANTL, H. TESCHEMACHER and F. LOTTSPEICH, Endogenous and Exogenous Opiate Agonists and Antagonists. E.L. WAY (ed) 233-236 Pergamon Press New York (1980)
2. 2. F. NYBERG and V. BRANTL (eds.), β - casomorphins and related peptides Fyris-Tryck AB, Uppsala, Sweden. (1990)
3. 3. J.E. ZADINA, L. HACKLER, L.J. GE and A.J. KASTIN, Nature 386 499-502. (1997)
4. 4. Z.H. GALINA and A.J. KASTIN, Life Science 39 2153-2159. (1986)
5. 5. B.P. ROQUES, M. FOURNIÉ-ZALUSKI, E. SOROCA, J.M. LECOMTE, B. MALFROY, C. LLORENS and J.-C. SCHWARTZ, Nature 288 286-288. (1980)
6. 6. P.L. WOOD and L.R. HUDGIN, Quo vadis? Analgesia & Enkephalinases, J. CROS, M. MORRE, J.P. MUYARD and R. RONCUCCI(eds.), 223-231 Sanofi Recherche, Montpellier (1984)
7. 7. A.Z. ZHANG, H.Y.T. YANG and E. COSTA, Neuropharmacology 21 625-630. (1982)
8. 8. J. COSTENTIN, A. VLAICULESCU, P. CHAILLET, L. BEN NATAN, D. AVEAUX and J.C. SCHWARTZ, Eur. J. Pharmacol. 123 37-44. (1986)
9. 9. R. WALTER, W.H. SIMMONS and T. YOSHIMOTO, Mol. Cell. Biochem. 30 111-127 (1980)
10. 10. E. ENDRÕCZI, J. HEPP, M. SASVÁRY, S. WALENTIN and G. LÉVAI, Acta Physiol. Hung. 73 35-44. (1990)
11. 11. H. UMEZAWA, T. AOYAGI, K. OGAWA, H. NAGANAWA, M. HAMADA and T. TAKEUCHI, J. Antibiotics, XXXVII 422-425. (1984)
12. 12. J.I. SZÉKELY, A.Z. RÓNAI, ZS. DUNAI-KOVÁCS, L. GRÁF and S. BAJUSZ, Experientia 33 54-55. (1977)
13. 13. A.Z. RÓNAI, L. GRÁF, J.I. SZÉKELY, ZS. DUNAI-KOVÁCS and S. BAJUSZ, FEBS Lett. 74 182-184. (1977)
14. 14. J.T. LITCHFIELD JR. and F. WILCOXON, J. Pharmacol. Exp. Ther. 96 99-113. (1949)
15. nd ed, Prentiss-Hall Inc. (1984)
16. th printing, Iowa State University Press. (1994)
17. 17. O. ARUNLAKSHANA and H.O. SCHILD, Br. J. Pharmacol. 14 48-58 (1959).
18. 18. H.W. KOSTERLITZ and A.J. WATT, Br. J. Pharmacol. 33 266-276. (1968)
19. 19. F.M. LESLIE, Pharmacol. Rew. 39 197-249. (1987)
20. 20. K.J. CHANG, A. KILLIAN, E. HAZUM and P. CUATRECASAS, Science 212, 75-77 (1981)
21. 21. J.I. SZÉKELY, Opioid Peptides Vol II. (by J.I. SZÉKELY and A.Z. RÓNAI) 109-154, CRC Press, Boca Raton. (1982)
22. 22. L. GRÁF, J.I. SZÉKELY, A.Z. RÓNAI, ZS. DUNAI-KOVÁCS and S. BAJUSZ, Nature 263 240-241. (1976)
23. 23. T.L. YAKSH and G.M. HARTY, Eur. J. Pharmacol. 79 293-300. (1982)
24. 24. R.E. CHIPKIN, L.C. IORIO, A. BARNETT, J. BERGER and W. BILLARD, Regulatory Peptides: From Molecular Biology to Function. E. COSTA and M. TRABUCCHI (eds) Raven Press, New York (1982)
25. 25. L. HACKLER, J.E. ZADINA and A.J. KASTIN, Peptides 18 1635-1639 (1997)
26. 26. M.S. SCHILD, J.E. ZADINA, S. VIGH and A.J. KASTIN, Peptides 18 1641-1649 (1997)