Attenuation of MPTP-induced neurotoxicity and locomotor dysfunction in Nucling-deficient mice via suppression of the apoptosome pathway

Journal of Neurochemistry

Volumn 97, Issue 4, 2006, Pages 1126-1135

  Teng, Xichuan ^a   Sakai, Takashi ^a   Liu, Li ^a   Sakai, Rika ^a,b   Kaji, Ryuji ^b   Fukui, Kiyoshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Apoptosis; Apoptosome; MPTP; Nucling; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 9; CELL PROTEIN; CYTOCHROME C; NUCLING; PROCASPASE 9; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION; LOCOMOTION; MALE; MOUSE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OPEN FIELD BEHAVIOR; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 9; CASPASES; CYTOCHROMES C; DISEASE MODELS, ANIMAL; DOPAMINE; DRUG RESISTANCE; GENETIC PREDISPOSITION TO DISEASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; MPTP POISONING; NERVE DEGENERATION; NEURONS; PARKINSONIAN DISORDERS; PROTEINS; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; UP-REGULATION;

ANIMALIA;

EID: 33646098900     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03833.x     Document Type: Article

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