Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 11, 2006, Pages 2955-2959

  Löber, Stefan ^a   Hübner, Harald ^a   Gmeiner, Peter ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

D4; Dopamine; Partial agonist; Regioselective synthesis; Subtype selectivity

Indexed keywords

DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; SEROTONIN RECEPTOR; TRIAZOLE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ASSAY; EVALUATION; LIGAND BINDING; MITOGENESIS; RECEPTOR AFFINITY; SUBSTITUTION REACTION;

MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, DOPAMINE D4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33646056943     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.075     Document Type: Article

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