Cytoplasmic Listeria monocytogenes stimulates IFN-β synthesis without requiring the adapter protein MAVS

FEBS Letters

Volumn 580, Issue 9, 2006, Pages 2341-2346

  Soulat, Didier ^a   Bauch, Angela ^b   Stockinger, Silvia ^a   Superti Furga, Giulio ^b   Decker, Thomas ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Gene expression; Infection; Innate immunity; Interferon; Macrophage; Signal transduction

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; INTERFERON REGULATORY FACTOR 3; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; MITOCHONDRIAL PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOPLASM; GENE SYNTHESIS; GRAM POSITIVE BACTERIUM; LISTERIA MONOCYTOGENES; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CYTOPLASM; INTERFERON-BETA; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

ANIMALIA; BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES; POSIBACTERIA;

EID: 33645991548     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.057     Document Type: Article

References (26)

1. Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
2. Bauer S. Toll-erating self DNA. Nat. Immunol. 7 (2006) 13-15
3. Jefferies C.A., and Fitzgerald K.A. Interferon gene regulation: not all roads lead to Tolls. Trends Mol. Med. 11 (2005) 403-411
4. Martinon F., and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26 (2005) 447-454
5. Decker T., Muller M., and Stockinger S. The yin and yang of type I interferon activity in bacterial infection. Nat. Rev. Immunol. 5 (2005) 675-687
6. Honda K., Yanai H., Takaoka A., and Taniguchi T. Regulation of the type I IFN induction: a current view. Int. Immunol. 17 (2005) 1367-1378
7. Levy D.E., and Darnell Jr. J.E. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3 (2002) 651-662
8. Kawai T., et al. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6 (2005) 981-988
9. Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., Bartenschlager R., and Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437 (2005) 1167-1172
10. Seth R.B., Sun L., Ea C.K., and Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122 (2005) 669-682
11. Xu L.G., Wang Y.Y., Han K.J., Li L.Y., Zhai Z., and Shu H.B. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19 (2005) 727-740
12. Portnoy D.A., Auerbuch V., and Glomski I.J. The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J. Cell Biol. 158 (2002) 409-414
13. O'Riordan M., Yi C.H., Gonzales R., Lee K.D., and Portnoy D.A. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. USA 99 (2002) 13861-13866
14. Stockinger S., et al. Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes. J. Immunol. 169 (2002) 6522-6529
15. Stockinger S., et al. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173 (2004) 7416-7425
16. O'Connell R.M., Vaidya S.A., Perry A.K., Saha S.K., Dempsey P.W., and Cheng G. Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. J. Immunol. 174 (2005) 1602-1607
17. Stetson D.B., and Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24 (2006) 93-103
18. Ishii K.J., et al. A toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7 (2006) 40-48
19. Kocks C., Gouin E., Tabouret M., Berche P., Ohayon H., and Cossart P. L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 68 (1992) 521-531
20. Kovarik P., Stoiber D., Novy M., and Decker T. Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation. Embo J. 17 (1998) 3660-3668
21. Kovarik P., et al. Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. Embo J. 20 (2001) 91-100
22. Heid C.A., Stevens J., Livak K.J., and Williams P.M. Real time quantitative PCR. Genome Res. 6 (1996) 986-994
23. Sledz C.A., Holko M., de Veer M.J., Silverman R.H., and Williams B.R. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 5 (2003) 834-839
24. Alexopoulou L., Holt A.C., Medzhitov R., and Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by toll-like receptor 3. Nature 413 (2001) 732-738
25. Andrejeva J., Childs K.S., Young D.F., Carlos T.S., Stock N., Goodbourn S., and Randall R.E. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc. Natl. Acad. Sci. USA 101 (2004) 17264-17269
26. Yoneyama M., et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5 (2004) 730-737