Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

Molecular Therapy

Volumn 13, Issue 5, 2006, Pages 987-996

  Sakata, Susumu ^a,b   Lebeche, Djamel ^a   Sakata, Yuri ^a   Sakata, Naoya ^a   Chemaly, Elie R ^a   Liang, Li Fan ^a   Padmanabhan, Prabhu ^a   Konishi, Noboru ^b   Takaki, Miyako ^b   del Monte, Federica ^a   Hajjar, Roger J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

diabetes mellitus; energetic function; gene therapy; heart failure; SERCA2a

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOVIRUS VECTOR; BETA GALACTOSIDASE; OXYGEN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE RELAXATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXYGEN CONSUMPTION; RANDOMIZATION; RAT; SARCOPLASMIC RETICULUM; SYSTOLIC BLOOD PRESSURE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; BLOOD GLUCOSE; BLOOD PRESSURE; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CARDIOMYOPATHIES; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MALE; MYOCARDIUM; RANDOM ALLOCATION; RATS; RATS, INBRED OLETF; RATS, INBRED STRAINS; SARCOPLASMIC RETICULUM; VENTRICULAR FUNCTION, LEFT;

ADENOVIRIDAE; ANIMALIA;

EID: 33645901857     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2006.01.002     Document Type: Article

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