GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells

Molecular and Cellular Biology

Volumn 26, Issue 8, 2006, Pages 3060-3070

  Resendes, Karen K ^a,c   Rosmarin, Alan G ^a,b,c  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

^c RHODE ISLAND HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTEGRIN; BINDING PROTEIN; CD18 ANTIGEN; DNA BINDING PROTEIN; ENHANCEOSOME; GA BINDING PROTEIN; GA BINDING PROTEIN ALPHA; PROTEIN P300; PROTEIN SUBUNIT; RETINOIC ACID; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME ANALYSIS; CHROMOSOME CONFORMATION CAPTURE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RETINOIC ACID RESPONSE ELEMENT; TRANSCRIPTION REGULATION;

ANTIGENS, CD18; BINDING SITES; CELL LINE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; E1A-ASSOCIATED P300 PROTEIN; ENHANCER ELEMENTS (GENETICS); GA-BINDING PROTEIN TRANSCRIPTION FACTOR; HUMANS; MODELS, GENETIC; MYELOID CELLS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; TRANS-ACTIVATION (GENETICS); TRETINOIN; U937 CELLS;

EID: 33645808905     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.26.8.3060-3070.2006     Document Type: Article

References (43)

1. Alvarez, M., S. J. Rhodes, and J. P. Bidwell. 2003. Context-dependent transcription: all politics is local. Gene 313:43-57.
2. Arany, Z., L. E. Huang, R. Eckner, S. Bhattacharya, C. Jiang, M. A. Goldberg, H. F. Bunn, and D. M. Livingston. 1996. An essential role for p300/CBP in the cellular response to hypoxia. Proc. Natl. Acad. Sci. USA 93:12969-12973.
3. Arnaout, M. A. 1990. Structure and function of the leukocyte adhesion molecules CD11/CD18. Blood 75:1037-1050.
4. Blobel, G. A. 2001. CREB-binding protein and p300: molecular integrators of hematopoietic transcription. Blood 2000 95:745-755.
5. Breitman, T. R., S. E. Selonick, and S. J. Collins. 1980. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc. Natl. Acad. Sci. USA 77:2936-2940.
6. Bush, T. S., M. St. Coeur, K. K. Resendes, and A. G. Rosmarin. 2003. GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells. Blood 101:311-317.
7. Chakravarti, D., V. J. LaMorte, M. C. Nelson, T. Nakajima, I. G. Schulman, H. Juguilon, M. Montminy, and R. M. Evans. 1996. Role of CBP/P300 in nuclear receptor signalling. Nature 383:99-103.
8. Chan, H. M., and N. B. La Thangue. 2001. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell Sci. 114:2363-2373.
9. Chinenov, Y., M. Henzl, and M. E. Martin. 2000. The alpha and beta subunits of the GA-binding protein form a stable heterodimer in solution. Revised model of heterotetrameric complex assembly. J. Biol. Chem. 275:7749-7756.
10. Collins, S. J., K. A. Robertson, and L. Mueller. 1990. Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-α). Mol. Cell. Biol. 10:2154-2163.
11. Dekker, J., K. Rippe, M. Dekker, and N. Kleckner. 2002. Capturing chromosome conformation. Science 295:1306-1311.
12. Foulds, C. E., M. L. Nelson, A. G. Blaszczak, and B. J. Graves. 2004. Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Mol. Cell. Biol. 24:10954-10964.
13. Gaines, P., and N. Berliner. 2003. Retinoids in myelopoiesis. J. Biol. Regul. Homeost. Agents 17:46-65.
14. Hao, H., H. Qi, and M. Ratnam. 2003. Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites. Blood 101:4551-4560.
15. Hickstein, D. D., M. J. Hickey, and S. J. Collins. 1988. Transcriptional regulation of the leukocyte adherence protein β subunit during human myeloid cell differentiation. J. Biol. Chem. 263:13863-13867.
16. Jousset, C., C. Carron, A. Boureux, C. T. Quang, C. Oury, I. Dusanter-Fourt, M. Charon, J. Levin, O. Bernard, and J. Ghysdael. 1997. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J. 16:69-82.
17. Melnick, A., and J. D. Licht. 1999. Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93:3167-3215.
18. Merchiers, P., F. Bulens, A. De Vriese, D. Collen, and A. Belayew. 1999. Involvement of Sp1 in basal and retinoic acid induced transcription of the human tissue-type plasminogen activator gene. FEBS Lett. 456:149-154.
19. Merika, M., and D. Thanos. 2001. Enhanceosomes. Curr. Opin. Genet. Dev. 11:205-208.
20. Merika, M., A. J. Williams, G. Chen, T. Collins, and D. Thanos. 1998. Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription. Mol. Cell 1:277-287.
21. Nickel, J., M. L. Short, A. Schmitz, M. Eggert, and R. Renkawitz. 1995. Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding. Nucleic Acids Res. 23:4785-4792.
22. Nuchprayoon, I., J. Shang, C. P. Simkevich, M. Luo, A. G. Rosmarin, and A. D. Friedman. 1999. An enhancer located between the neutrophil elastase and proteinase 3 promoters is activated by Sp1 and an Ets factor. J. Biol. Chem. 274:1085-1091.
23. Rosmarin, A. G., D. Caprio, R. Levy, and C. Simkevich. 1995. CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity. Proc. Natl. Acad. Sci. USA 92:801-805.
24. 2 leukocyte integrin) transcription. J. Biol. Chem. 270:23627-23633.
25. Rosmarin, A. G., R. Levy, and D. G. Tenen. 1992. Cloning and analysis of the CD18 promoter. Blood 79:2598-2604.
26. Rosmarin, A. G., M. Luo, D. G. Caprio, J. Shang, and C. P. Simkevich. 1998. Sp1 cooperates with the ets transcription factor, GABP, to activate the CD18 (β2 leukocyte integrin) promoter. J. Biol. Chem. 273:13097-13103.
27. Rosmarin, A. G., K. K. Resendes, Z. Yang, J. N. McMillan, and S. L. Fleming. 2004. GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions. Blood Cells Mol. Dis. 32:143-154.
28. Rosmarin, A. G., Z. Yang, and K. K. Resendes. 2005. Transcriptional regulation in myelopoiesis: hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Exp. Hematol. 33:131-143.
29. Sadasivan, E., M. M. Cedeno, and S. P. Rothenberg. 1994. Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein. J. Biol. Chem. 269:4725-4735.
30. Scholz, H., J. Deatrick, A. Klaes, and C. Klämbt. 1993. Genetic dissection of pointed, a Drosophila gene encoding two ETS-related proteins. Genetics 135:455-468.
31. Schweppe, R. E., A. A. Melton, K. S. Brodsky, L. D. Aveline, K. A. Resing, N. G. Ahn, and A. Gutierrez-Hartmann. 2003. Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter. J. Biol. Chem. 278:16863-16872.
32. Seidel, J. J., and B. J. Graves. 2002. An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes Dev. 16:127-137.
33. Sharrocks, A. D. 2001. The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2:827-837.
34. Shibata, H., T. E. Spencer, S. A. Onate, G. Jenster, S. Y. Tsai, M. J. Tsai, and B. W. O'Malley. 1997. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog. Horm. Res. 52:141-164.
35. Shimada, J., Y. Suzuki, S. J. Kim, P. C. Wang, M. Matsumura, and S. Kojima. 2001. Transactivation via RAR/RXR-Sp1 interaction: characterization of binding between Sp1 and GC box motif. Mol. Endocrinol. 15:1677-1692.
36. Shivdasani, R. A., and S. H. Orkin. 1996. The transcriptional control of hematopoiesis. Blood 87:4025-4039.
37. Skalnik, D. G. 2002. Transcriptional mechanisms regulating myeloid-specific genes. Gene 284:1-21.
38. Slupsky, C. M., L. N. Gentile, L. W. Donaldson, C. D. Mackereth, J. J. Seidel, B. J. Graves, and L. P. McIntosh. 1998. Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site. Proc. Natl. Acad. Sci. USA 95:12129-12134.
39. Suzuki, Y., J. Shimada, K. Shudo, R. Matsumura, M. P. Crippa, and S. Kojima. 1999. Physical interaction between retinoic acid receptor and Sp1: mechanism for induction of urokinase by retinoic acid. Blood 93:4264-4276.
40. Todd, R. F., and D. R. Freyer. 1988. The CD11/CD18 leukocyte glycoprotein deficiency. Hematol. Oncol. Clin. North Am. 2:13-31.
41. Tsytsykova, A. V., and A. E. Goldfeld. 2002. Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes. Mol. Cell. Biol. 22:2620-2631.
42. Vakoc, C. R., D. L. Letting, N. Gheldof, T. Sawado, M. A. Bender, M. Groudine, M. J. Weiss, J. Dekker, and G. A. Blobel. 2005. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol. Cell 17:453-462.
43. Yang, C., L. H. Shapiro, M. Rivera, A. Kumar, and P. K. Brindle. 1998. A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions. Mol. Cell. Biol. 18:2218-2229.