GA-binding protein transcription factor: A review of GABP as an integrator of intracellular signaling and protein-protein interactions

Blood Cells, Molecules, and Diseases

Volumn 32, Issue 1, 2004, Pages 143-154

  Rosmarin, Alan G ^a,b   Resendes, Karen K ^a   Yang, Zhongfa ^a   McMillan, John N ^b   Fleming, Shawna L ^b  

^a BROWN UNIVERSITY   (United States)

^b MIRIAM HOSPITAL   (United States)

Author keywords

GABP; Genes; Transcription factor

Indexed keywords

BINDING PROTEIN; GA BINDING PROTEIN; GA BINDING PROTEIN ALPHA; GA BINDING PROTEIN BETA; HORMONE DERIVATIVE; MEMBRANE RECEPTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; NUCLEAR FACTOR; PROTEIN DERIVATIVE; PROTEIN P300; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

BONE MARROW CELL; CELL CYCLE; CELL FUNCTION; CELL LINEAGE; CELL METABOLISM; COMPLEX FORMATION; DOWNSTREAM PROCESSING; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; GENETIC LINE; GENETIC TRANSCRIPTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REGULATOR GENE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; VIRUS GENE;

NEXUS;

EID: 0742306875     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2003.09.005     Document Type: Article

References (107)

1. Dittmer J., Nordheim A. Ets transcription factors and human disease. Biochim. Biophys. Acta Rev. Cancer. 1377:1998;F1-F11.
2. Ghosh A., Kolodkin A.L. Specification of neuronal connectivity: ETS marks the spot. Cell. 95:1998;303-306.
3. Bassuk A.G., Leiden J.M. The role of Ets transcription factors in the development and function of the mammalian immune system. Adv. Immunol. 64:1997;65-104.
4. Wasylyk B., Hagman J., Gutierrez-Hartmann A. Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biochem. Sci. 23:1998;213-216.
5. Graves B.J., Petersen J.M. Specificity within the ets family of transcription factors. Adv. Cancer Res. 75:1998;1-55.
6. Sharrocks A.D., Brown A.L., Ling Y., Yates P.R. The ETS-domain transcription factor family. Int. J. Biochem. Cell Biol. 29:1997;1371-1387.
7. Thompson C.C., Brown T.A., McKnight S.L. Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complex. Science. 253:1991;762-768.
8. LaMarco K., Thompson C.C., Byers B.P., Walton E.M., McKnight S.L. Identification of Ets- and notch-related subunits in GA binding protein. Science. 253:1991;789-792.
9. Brown T.A., McKnight S.L. Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. Genes Dev. 6:1992;2502-2512.
10. Watanabe H., Wada T., Handa H. Transcription factor E4TF1 contains two subunits with different functions. EMBO J. 9:1990;841-847.
11. Gugneja S., Virbasius C.M.A., Scarpulla R.C. Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription. Mol. Cell. Biol. 16:1996;5708-5716.
12. Bolwig G.M., Bruder J.T., Hearing P. Different binding site requirements for binding and activation for the bipartite enhancer factor EF-1A. Nucleic Acids Res. 20:1992;6555-6564.
13. Savoysky E.et al. The retinoblastoma binding factor 1 (RBF-1) site in RB gene promoter binds preferentially E4TF1, a member of the Ets transcription factors family. Oncogene. 9:1994;1839-1846.
14. Marchioni M., Morabito S., Salvati A.L., Beccari E., Carnevali F. XrpFI, an amphibian transcription factor composed of multiple polypeptides immunologically related to the GA-binding protein alpha and beta subunits, is differentially expressed during Xenopus laevis development. Mol. Cell. Biol. 13:1993;6479-6489.
15. Yoganathan T., Bhat N.K., Sells B.H. A positive regulator of the ribosomal protein gene, b factor, belongs to the ETS oncoprotein family. Biochem. J. 287:1992;349-353.
16. Oikawa T., Yamada T. Molecular biology of the Ets family of transcription factors. Gene. 303:2003;11-34.
17. Sharrocks A.D. The ETS-domain transcription factor family. Nat. Rev., Mol. Cell Biol. 2:2001;827-837.
18. Virbasius J.V., Virbasius C.A., Scarpulla R.C. Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters. Genes Dev. 7:1993;380-392.
19. Sawada J., Goto M., Sawa C., Watanabe H., Handa H. Transcriptional activation through the tetrameric complex formation of E4TF1 subunits. EMBO J. 13:1994;1396-1402.
20. Gugneja S., Virbasius J.V., Scarpulla R.C. Four structurally distinct, non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domain, Mol. Cell. Biol. 15:1995;102-111.
21. Batchelor A.H., Piper D.E., De la Brousse F.C., McKnight S.L., Wolberger C. The structure of GABPa/b: an ETS domain ankyrin repeat heterodimer bound to DNA. Science. 279:1998;1037-1041.
22. Chinenov Y., Henzl M., Martin M.E. The alpha and beta subunits of the GA-binding protein form a stable heterodimer in solution. Revised model of heterotetrameric complex assembly. J. Biol. Chem. 275:2000;7749-7756.
23. Golub T.R., Barker G.F., Lovett M., Gilliland D.G. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell. 77:1994;307-316.
24. McLean T.W.et al. TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia. Blood. 88:1996;4252-4258.
25. Jousset C.et al. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J. 16:1997;69-82.
26. Bush T.S., St Coeur M., Resendes K.K., Rosmarin A.G. GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells. Blood. 101:2003;311-317.
27. Luo M.et al. Characterization and localization to chromosome 7 of psihGABPalpha, a human processed pseudogene related to the ets transcription factor, hGABPalpha. Gene. 234:1999;119-126.
28. De la Brousse F.C., Birkenmeier E.H., King D.S., Rowe L.B., McKnight S.L. Molecular and genetic characterization of GABPb. Genes Dev. 8:1994;1853-1865.
29. Sedgwick S.G., Smerdon S.J. The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem. Sci. 24:1999;311-316.
30. Sawa C., Goto M., Suzuki F., Watanabe H., Sawada J., Handa H. Functional domains of transcription factor hGABP beta1/E4TF1-53 required for nuclear localization and transcription activation. Nucleic Acids Res. 24:1996;4954-4961.
31. Gugneja S., Virbasius C.M., Scarpulla R.C. Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription. Mol. Cell. Biol. 16:1996;5708-5716.
32. Flory E., Hoffmeyer A., Smola U., Rapp U.R., Bruder J.T. Raf-1 kinase targets GA-binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter. J. Virol. 70:1996;2260-2268.
33. Rosmarin A.G., Caprio D.G., Kirsch D.G., Handa H., Simkevich C.P. GABP and PU.1 compete for binding, yet cooperate to increase CD18 (b2 leukocyte integrin) transcription. J. Biol. Chem. 270:1995;23627-23633.
34. Böttinger E.P., Shelley C.S., Farokhzad O.C., Arnaout M.A. The human b2 integrin CD18 promoter consists of two inverted Ets cis elements. Mol. Cell. Biol. 14:1994;2604-2615.
35. Rosen G.D., Barks J.L., Iademarco M.F., Fisher R.J., Dean D.C. An intricate arrangement of binding sites for the Ets family of transcription factors regulates activity of the a4 integrin gene promoter. J. Biol. Chem. 269:1994;15652-15660.
36. Nickel J., Short M.L., Schmitz A., Eggert M., Renkawitz R. Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding. Nucleic Acids Res. 23:1995;4785-4792.
37. Nuchprayoon I., Simkevich C.P., Luo M.L., Friedman A.D., Rosmarin A.G. GABP cooperates with c-Myb and C/EBP to activate the neutrophil elastase promoter. Blood. 89:1997;4546-4554.
38. Sadasivan E., Cedeno M.M., Rothenberg S.P. Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein. J. Biol. Chem. 269:1994;4725-4735.
39. Rosmarin A.G., Weil S.C., Rosner G.L., Griffin J.D., Arnaout M.A., Tenen D.G. Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation. Blood. 73:1989;131-136.
40. Hickstein D.D., Hickey M.J., Collins S.J. Transcriptional regulation of the leukocyte adherence protein b subunit during human myeloid cell differentiation. J. Biol. Chem. 263:1988;13863-13867.
41. Rosmarin A.G., Caprio D., Levy R., Simkevich C. CD18 (beta 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity. Proc. Natl. Acad. Sci. U. S. A. 92:1995;801-805.
42. Rosmarin A.G., Luo M., Caprio D.G., Shang J., Simkevich C.P. Sp1 cooperates with the ets transcription factor, GABP, to activate the CD18 (beta2 leukocyte integrin) promoter. J. Biol. Chem. 273:1998;13097-13103.
43. Gaines P., Berliner N. Retinoids in myelopoiesis. J. Biol. Regul. Homeostatic Agents. 17:2003;46-65.
44. Rosmarin A.G., Weil S.C., Rosner G.L., Griffin J.D., Arnaout M.A., Tenen D.G. Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation. Blood. 73:1989;131-136.
45. Hao H., Qi H., Ratnam M. Modulation of the folate receptor type beta gene by coordinate actions of retinoic acid receptors at activator Sp1/ets and repressor AP-1 sites. Blood. 101:2003;4551-4560.
46. Rahman A., Esmaili A., Saatcioglu F. A unique thyroid hormone response element in the human immunodeficiency virus type 1 long terminal repeat that overlaps the Sp1 binding sites. J. Biol. Chem. 270:1995;31059-31064.
47. Ouyang L.H., Jacob K.K., Stanley F.M. GABP mediates insulin-increased prolactin gene transcription. J. Biol. Chem. 271:1996;10425-10428.
48. Schweppe R.E., Gutierrez-Hartmann A. Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter. Nucleic Acids Res. 29:2002;1251-1260.
49. Avots A., Hoffmeyer A., Flory E., Cimanis A., Rapp U.R., Serfling E. GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction. Mol. Cell. Biol. 17:1997;4381-4389.
50. Li X.R.et al. Transcriptional regulation of Fas gene expression by GA-binding protein and AP-1 in T cell antigen receptor. CD3 complex-stimulated T cells. J. Biol. Chem. 274:1999;35203-35210.
51. Bannert N., Avots A., Baier M., Serfling E., Kurth R. GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 96:1999;1541-1546.
52. Morii E.et al. Inhibitory effect of the mi transcription factor encoded by the mutant mi allele on GA binding protein-mediated transcript expression in mouse mast cells. Blood. 97:2002;3032-3039.
53. Briguet A., Ruegg M.A. The Ets transcription factor GABP is required for postsynaptic differentiation in vivo. J. Neurosci. 20:2002;5989-5996.
54. Schaeffer L., Duclert N., Huchet-Dymanus M., Changeux J.P. Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor. EMBO J. 17:1998;3078-3090.
55. Fromm L., Burden S.J. Synapse-specific and neuregulin-induced transcription require an ets site that binds GABPalpha/GABPbeta. Genes Dev. 12:1998;3074-3083.
56. Gramolini A.O.et al. Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein. Proc. Natl. Acad. Sci. U. S. A. 96:1999;3223-3227.
57. Khurana T.S., Rosmarin A.G., Shang J., Krag T.O., Das S., Gammeltoft S. Activation of utrophin promoter by heregulin via the ets-related transcription factor complex GA-binding protein alpha/beta. Mol. Biol. Cell. 10:1999;2075-2086.
58. Galvagni F., Capo S., Oliviero S. Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter. J. Mol. Biol. 306:2002;985-996.
59. Gyrd-Hansen M., Krag T.O., Rosmarin A.G., Khurana T.S. Sp1 and the ets-related transcription factor complex GABP alpha/beta functionally cooperate to activate the utrophin promoter. J. Neurol. Sci. 197:2002;27-35.
60. Khurana T.S., Davies K.E. Pharmacological strategies for muscular dystrophy. Nat. Rev., Drug Discov. 2:2003;379-390.
61. Virbasius J.V., Virbasius C.A., Scarpulla R.C. Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters. Genes Dev. 7:1993;380-392.
62. Carter R.S., Avadhani N.G. Cooperative binding of GA-binding protein transcription factors to duplicated transcription initiation region repeats of the cytochrome c oxidase subunit IV gene. J. Biol. Chem. 269:1994;4381-4387.
63. Sucharov C., Basu A., Carter R.S., Avadhani N.G. A novel transcriptional initiator activity of the GABP factor binding ets sequence repeat from the murine cytochrome c oxidase Vb gene. Gene Expression. 5:1995;93-111.
64. Martin M.E., Chinenov Y., Yu M., Schmidt T.K., Yang X.Y. Redox regulation of GA-binding protein-alpha DNA binding activity. J. Biol. Chem. 271:1996;25617-25623.
65. Seelan R.S., Gopalakrishnan L., Scarpulla R.C., Grossman L.I. Cytochrome c oxidase subunit VIIa liver isoform. Characterization and identification of promoter elements in the bovine gene. J. Biol. Chem. 271:1996;2112-2120.
66. Villena J.A., Vinas O., Mampel T., Iglesias R., Giralt M., Villarroya F. Regulation of mitochondrial biogenesis in brown adipose tissue: nuclear respiratory factor-2/GA-binding protein is responsible for the transcriptional regulation of the gene for the mitochondrial ATP synthase beta subunit. Biochem. J. 331:1998;121-127.
67. Curcic D., Glibetic M., Larson D.E., Sells B.H. GA-binding protein is involved in altered expression of ribosomal protein L32 gene. J. Cell. Biochem. 65:1997;287-307.
68. Genuario R.R., Kelley D.E., Perry R.P. Comparative utilization of transcription factor GABP by the promoters of ribosomal protein genes rpL30 and rpL32. Gene Expression. 3:1993;279-288.
69. Shiio Y., Sawada J.I., Handa H., Yamamoto T., Inoue J.I. Activation of the retinoblastoma gene expression by Bcl-3: implication for muscle cell differentiation. Oncogene. 12:1996;1837-1845.
70. Sowa Y.et al. Retinoblastoma binding factor 1 site in the core promoter region of the human RB gene is activated by hGABP/E4TF1. Cancer Res. 57:1997;3145-3148.
71. Hauck L., Kaba R.G., Lipp M., Dietz R., von Harsdorf R. Regulation of E2F1-dependent gene transcription and apoptosis by the ETS-related transcription factor GABPgamma1. Mol. Cell. Biol. 22:2002;2147-2158.
72. Izumi M.et al. Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1. Biochim. Biophys. Acta. 1492:2002;341-352.
73. Rudge T.L., Johnson L.F. Synergistic activation of the TATA-less mouse thymidylate synthase promoter by the Ets transcription factor GABP and Sp1. Exp. Cell Res. 274:2002;45-55.
74. Watanabe H., Imai T., Sharp P.A., Handa H. Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4. Mol. Cell. Biol. 8:1988;1290-1300.
75. Sun W., Graves B.J., Speck N.A. Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins. J. Virol. 69:1995;4941-4949.
76. Douville P., Hagmann M., Georgiev O., Schaffner W. Positive and negative regulation at the herpes simplex virus ICP4 and ICP0 TAATGARAT motifs. Virology. 207:1995;107-116.
77. Vogel J.L., Kristie T.M. The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP. EMBO J. 19:2002;683-690.
78. Vassias I.et al. Regulation of human B19 parvovirus promoter expression by hGABP (E4TF1) transcription factor. J. Biol. Chem. 273:1998;8287-8293.
79. Verhoef K., Sanders R.W., Fontaine V., Kitajima S., Berkhout B. Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site. J. Virol. 73:1999;1331-1340.
80. Schweppe R.E.et al. Purification and mass spectrometric identification of GA-binding protein (GABP) as the functional pituitary Ets factor binding to the basal transcription element of the prolactin promoter. J. Biol. Chem. 278:2003;16863-16872.
81. Kamura T., Handa H., Hamasaki N., Kitajima S. Characterization of the human thrombopoietin gene promoter - A possible role of an Ets transcription factor, E4TF1/GABP. J. Biol. Chem. 272:1997;11361-11368.
82. Tomaras G.D., Foster D.A., Burrer C.M., Taffet S.M. ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha. J. Leukocyte Biol. 66:1999;183-193.
83. Markiewicz S.et al. Tissue-specific activity of the gammac chain gene promoter depends upon an Ets binding site and is regulated by GA-binding protein. J. Biol. Chem. 271:1996;14849-14855.
84. Hoare S., Copland J.A., Wood T.G., Jeng Y.J., Izban M.G., Soloff M.S. Identification of a GABP alpha/beta binding site involved in the induction of oxytocin receptor gene expression in human breast cells, potentiation by c-Fos/c-Jun. Endocrinology. 140:1999;2268-2279.
85. Yokomori N., Tawata M., Saito T., Shimura H., Onaya T. Regulation of the rat thyrotropin receptor gene by the methylation-sensitive transcription factor GA-binding protein. Mol. Endocrinol. 12:1998;1241-1249.
86. Hoffmeyer A., Avots A., Flory E., Weber C.K., Serfling E., Rapp U.R. The GABP-responsive element of the interleukin-2 enhancer is regulated by JNK/SAPK-activating pathways in T lymphocytes. J. Biol. Chem. 273:1998;10112-10119.
87. Fromm L., Burden S.J. Neuregulin-1-stimulated phosphorylation of GABP in skeletal muscle cells. Biochemistry. 40:2002;5306-5312.
88. 2 leukocyte integrin) promoter requires PU.1 transcription factor for myeloid activity. Proc. Natl. Acad. Sci. U. S. A. 92:1995;801-805.
89. Cowley D.O., Graves B.J. Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition. Genes Dev. 14:2000;366-376.
90. Sawada J.et al. Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family. J. Biol. Chem. 274:1999;35475-35482.
91. Atlas E., Stramwasser M., Whiskin K., Mueller C.R. GA-binding protein a/ b is a critical regulator of the BRCA1 promoter. Oncogene. 19:2000;1933-1940.
92. Jiang P.et al. Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity. J. Biol. Chem. 277:2002;8989-8998.
93. Rao M.K., Maiti S., Ananthaswamy H.N., Wilkinson M.F. A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types. J. Biol. Chem. 277:2002;26036-26045.
94. Scott E.W., Simon M.C., Anastasi J., Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science. 265:1994;1573-1577.
95. Anderson K.L., Smith K.A., Conners K., McKercher S.R., Maki R.A., Torbett B.E. Myeloid development is selectively disrupted in PU.1 null mice. Blood. 91:1998;3702-3710.
96. Mueller B.U.et al. Heterozygous PU.1 mutations are associated with acute myeloid leukemia. Blood. 100:2002;998-1007.
97. Oelgeschlager M., Nuchprayoon I., Luscher B., Friedman A.D. C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter. Mol. Cell. Biol. 16:1996;4717-4725.
98. Blobel G.A. CREB-binding protein and p300: molecular integrators of hematopoietic transcription. Blood. 95:2001;745-755.
99. Vo N., Goodman R.H. CREB-binding protein and p300 in transcriptional regulation. J. Biol. Chem. 276:2002;13505-13508.
100. Kung A.L.et al. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 14:2000;272-277.
101. Blobel G.A. CREB-binding protein and p300: molecular integrators of hematopoietic transcription. Blood. 95:2002;745-755.
102. Wilson A.C., LaMarco K., Peterson M.G., Herr W. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell. 74:1993;115-125.
103. Sawa C.et al. YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors. J. Biol. Chem. 277:2002;22484-22490.
104. Du K., Leu J.I., Peng Y., Taub R. Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals. J. Biol. Chem. 273:1998;35208-35215.
105. Mundle S.D., Saberwal G. Evolving intricacies and implications of E2F1 regulation. FASEB J. 17:2003;569-574.
106. Nishikawa N., Izumi M., Yokoi M., Miyazawa H., Hanaoka F. E2F regulates growth-dependent transcription of genes encoding both catalytic and regulatory subunits of mouse primase. Genes Cells. 6:2001;57-70.
107. Watanabe H., Sawada J., Yano K., Yamaguchi K., Goto M., Handa H. cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs. Mol. Cell. Biol. 13:1993;1385-1391.