Physical interaction between retinoic acid receptor and Sp1: Mechanism for induction of urokinase by retinoic acid

Blood

Volumn 93, Issue 12, 1999, Pages 4264-4276

  Suzuki, Yasuhiro ^b   Shimada, Jun ^b   Shudo, Koichi ^b   Matsumura, Masatoshi ^b   Crippa, Massimo P ^b   Kojima, Soichi ^a  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYCLOHEXIMIDE; MESSENGER RNA; RETINOIC ACID; RETINOIC ACID RECEPTOR; TRANSCRIPTION FACTOR SP1; UROKINASE;

ARTICLE; BINDING AFFINITY; ENZYME INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; VASCULAR ENDOTHELIUM;

EID: 0033564677     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.12.4264     Document Type: Article

References (59)

1. Chambon P: A decade of molecular biology of retinoic acid receptors. FASEB J 10:940, 1996
2. Mangelsdorf DJ, Evans RM: The RXR heterodimers and orphan receptors. Cell 83:841, 1995
3. Sucov HM, Murakami KK, Evans RM: Characterization of an autoregulated response element in the mouse retinoic acid receptor type β gene. Proc Natl Acad Sci USA 87:5392, 1990
4. Chen JD, Evans RM: A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454, 1995
5. Lin RJ, Nagy L, Inoue S, Shao W, Miller WH Jr, Evans RM: Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature 391:811, 1998
6. Oñate SA, Tsai SY, Tsai M-J, O'Malley BW: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354, 1995
7. Torchia J, Rose DW, Inostroza J, Kamei Y, Westin S, Glass CK, Rosenfeld MG: The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387:677, 1997
8. Bachmann F: The plasminogen-plasmin enzyme system, in Colman RW, Hirsh J, Marder VJ, Salzman EW (eds): Hemostasis and Thrombosis: Basic Principles and Clinical Practice (ed 3). Philadelphia, PA, Lippincott, 1994, p 1592
9. Hajjar KA, Nachman RL: The human endothelial cell plasmin-generating system, in Colman RW, Hirsh J, Marder VJ, Salzman EW (eds): Hemostasis and Thrombosis: Basic Principles and Clinical Practice (ed 3). Philadelphia, PA, Lippincott, 1994, p 823
10. Imai S, Okuno M, Moriwaki H, Muto Y, Murakami K, Shudo K, Suzuki Y, Kojima S: 9,13-di-cis-retinoic acid induces the production of tPA and activation of latent TGF-β via RARα in a human liver stellate cell line, LI90. FEBS Lett 411:102, 1997
11. Kojima S, Inui T, Muramatsu H, Suzuki Y, Kadomatsu K, Yoshizawa M, Hirose S, Kimura T, Sakakibara S, Muramatsu T: Dimerization of midkine by tissue transglutaminase and its functional implication. J Biol Chem 272:9410, 1997
12. Kojima S, Muramatsu H, Amanuma H, Muramatsu T: Midkine enhances fibrinolytic activity of bovine endothelial cells. J Biol Chem 270:9590, 1995
13. Kojima S, Nara K, Rifkin DB: Requirement for transglutaminase in the activation of latent transforming growth factor-β in bovine endothelial cells. J Cell Biol 121:439, 1993
14. Krätzschmar J, Haendler B, Kojima S, Rifkin DB, Schleuning W-D: Bovine urokinase-type plasminogen activator and its receptor: Cloning and induction by retinoic acid. Gene 125:177, 1993
15. Okuno M, Moriwaki H, Imai S, Muto Y, Kawada N, Suzuki Y, Kojima S: Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-β in liver stellate cells. Hepatology 26:913, 1997
16. Kagechika H, Kawachi E, Hashimoto Y, Himi T, Shudo K: Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity. J Med Chem 31:2182, 1988
17. Kagechika H, Himi T, Namikawa K, Kawachi E, Hashimoto Y, Shudo K: Retinobenzoic acids. 3. Structure-activity relationships of retinoidal azobenzene-4-carboxylic acids and stilbene-4-carboxylic acids. J Med Chem 32:1098, 1989
18. Eyrolles L, Kagechika H, Kawachi E, Fukasawa H, lijima T, Matsushima Y, Hashimoto Y, Shudo K: Retinobenzoic acids. 6. Retinoid antagonists with a heterocyclic ring. J Med Chem 37:1508, 1994
19. Gianni' M, Zanotta S, Terao M, Garattini S, Garattini E: Effects of synthetic retinoids and retinoic acid isomers on the expression of alkaline phosphatase in F9 teratocarcinoma cells. Biochem Biophys Res Commun 196:252, 1993
20. Bernard BA, Bernardon J-M, Delescluse C, Martin B, Lenoir M-C, Maignan J, Charpentier B, Pilgrim WR, Reichert U, Shroot B: Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor y, Biochem Biophys Res Commun 186:977, 1992
21. + erythroid progenitor cells. Blood 87:1728, 1996
22. Kanatani Y, Makishima M, Asahi K, Sakurai A, Takahashi N, Motoyoshi K, Nagata N, Honma Y: Differanisole A, a novel antitumor antibiotic, enhances growth inhibition and differentiation of human myeloid leukemia cells induced by 9-cis retinoic acid. Biochim Biophys Acta 1359:71, 1997
23. Apfel C, Bauer F, Crettaz M, Forni L, Kamber M, Kaufmann F, Lemotte P, Pirson W, Klaus M: A retinoic acid receptor α antagonist selectively counteracts retinoic acid effects. Proc Natl Acad Sci USA 89:7129, 1992
24. Benbrook D, Lernhardt E, Pfahl M: A new retinoic acid receptor identified from a hepatocellular carcinoma. Nature 333:669, 1988
25. Brand N, Petkovich M, Krust A, Chambon P, de Thé H, Marchio A, Tiollais P, Dejean A: Identification of a second human retinoic acid receptor. Nature 332:850, 1988
26. Krust A, Kastner P, Petkovich M, Zelent A, Chambon P: A third human retinoic acid receptor, hRAR-γ. Proc Natl Acad Sci USA 86:5310, 1989
27. Leid M, Kastner P, Lyons R, Nakshatri H, Saunders M, Zacharewski T, Chen J-Y, Staub A, Gamier J-M, Mader S, Chambon P: Purification, cloning, and RXR identity of the Hela cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell 68:377, 1992
28. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
29. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual (ed 2). Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
30. Verde P, Boast S, Franzè A, Robbiati F, Blasi F: An upstream enhancer and a negative element in the 5′ flanking region of the human urokinase plasminogen activator gene. Nucleic Acids Res 16:10699, 1988
31. Kato S, Sasaki H, Suzawa M, Masushige S, Tora L, Chambon P, Gronemeyer H: Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. Mol Cell Biol 15:5858, 1995
32. II 110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc Natl Acad Sci USA 91:192, 1994
33. Nagy L, Tontonoz P, Alvarez JGA, Chen H, Evans RM: Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93:229, 1998
34. Kadonaga JT, Courey AJ, Ladika J, Tjian R: Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science 242:1566, 1988
35. Dey A, Minucci S, Ozato K: Ligand-dependent occupancy of the retinoic acid receptor β2 Promoterin vivo. Mol Cell Biol 14:8191, 1994
36. Duan R, Porter W, Safe S: Estrogen-induced c-fos protooncogene expression in MCF-7 human breast cancer cells: Role of estrogen receptor Sp1 complex formation. Endocrinology 139:1981, 1998
37. Sun G, Porter W, Safe S: Estrogen-induced retinoic acid receptor al gene expression: role of estrogen receptor-Spl complex. Mol Endocrinol 12:882, 1998
38. Soravia E, Grebe A, De Luca P, Helin K, Suh TT, Degen JL, Blasi F: A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene. Blood 86:624, 1995
39. Lu S, Saydak M, Gentile V, Stein JP, Davies PJA: Isolation and characterization of the human tissue transglutarninase gene promoter. J Biol Chem 270:9748, 1995
40. Dynan WS, Tjian R: Isolation of transcription factors that discriminate between different promoters recognized by RNA polymer-ase II. Cell 32:669, 1983
41. Greenwel P, Inagaki Y, Hu W, Walsh M, Ramirez F: Sp1 is required for the early response of α2(I) collagen to transforming growth factor-β1. J Biol Chem 272:19738, 1997
42. Carpenter ML, Marks JN, Fox KR: DNA-sequence binding preference of the GC-selective ligand mithramycin. Deoxyribonuclease-I/deoxyribonuclease-II and hydroxy-radical footprinting at CCCG, CCGC, CGGC, GCCC and GGGG flanked by (AT)n and An·Tn. Eur J Biochem 215:561, 1993
43. Nehls MC, Brenner DA, Grass H-J, Dierbach H, Mertelsmann R, Herrmann F: Mithramycin selectively inhibits collagen-α1(I) gene expression in human fibroblast. J Clin Invest 92:2916, 1993
44. Rastinejad F, Perlmann T, Evans RM, Sigler PB: Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature 375:203, 1995
45. Renaud J-P, Rochel N, Ruff M, Vivat V, Chambon P, Gronemeyer H, Moras D: Crystal structure of the RAR-γ ligand-binding domain bound to all-rranj retinoic acid. Nature 378:681, 1995
46. Dolle P, Ruberte E, Leroy P, Morris-Kay G, Chambon P: Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110:1133, 1990
47. Ruberte E, Dolle P, Chambon P, Morris-Kay G: Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos. Development 111:45, 1991
48. Ruberte E, Friederich V, Chambon P, and Morris-Kay G: Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development. Development 118:267, 1993
49. Piedrafita FJ, Pfahl M: Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation. Mol Cell Biol 17:6348, 1997
50. Panariello L, Quadro L, Trematerra S, Colantuoni V: Identification of a novel retinoic acid response element in the promoter region of the retinol-binding protein gene. J Biol Chem 271:25524, 1996
51. WARI cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. J Biol Chem 273:10696, 1998
52. Rohr O, Aunis D, Schaeffer E: COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells. J Biol Chem 272:31149, 1997
53. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin S-C, Heyman RA, Rose DW, Glass CK, Rosenfeld MG: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403, 1996
54. Nagpal S, Cai J, Zheng T, Patel S, Masood R, Lin GY, Friant S, Johnson A, Smith DL, Chandraratna RAS, Gill PS: Retinoid antagonism of NF-IL6: Insight into the mechanism of antiproliferative effects of retinoids in Kaposi's sarcoma. Mol Cell Biol 17:4159, 1997
55. Pfitzner E, Kirfel J, Becker P, Rolke A, Schule R: Physical interaction between retinoic acid receptor and the oncoprotein Myb inhibits retinoic acid-dependent transactivation. Proc Natl Acad Sci USA 95:5539, 1998
56. Khachigian LM, Lindner V, Williams AJ, Collins T: Egr-1-induced endothelial gene expression: A common theme in vascular injury. Science 271:1427, 1996
57. Berthelsen J, Vandekerkhove J, Blasi F: Purification and characterization of UEF3, a novel factor involved in the regulation of the urokinase and other AP-1 controlled promoters. J Biol Chem 271:3822, 1996
58. De Cesare D, Palazzolo M, Blasi F: Functional characterization of COM, a DNA region required for cooperation between AP-1 sites in urokinase gene transcription. Oncogene 13:2551, 1996
59. De Cesare D, Palazzolo M, Berthelsen J, Blasi F: Characterization of UEF-4, a DNA-binding protein required for transcriptional synergism between two AP-1 sites in the human urokinase enhancer. J Biol Chem 272:23921, 1997