Role of perivascular cells and myocytes in vascular amyloidosis

Annals of the New York Academy of Sciences

Volumn 903, Issue , 2000, Pages 6-18

  Wisniewski, H M ^a   Wegiel, J ^a   Vorbrodt, A W ^a   Mazur Kolecka, B ^a   Frackowiak, J ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CYTOKINE; PREALBUMIN; PROTEIN PRECURSOR;

AGED; ALZHEIMER DISEASE; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONFERENCE PAPER; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MICROGLIA; MONOCYTE; MUSCLE CELL; NERVE CELL DEGENERATION; PROTEIN PROCESSING; SMOOTH MUSCLE FIBER; TUNICA MEDIA; VASCULAR AMYLOIDOSIS; VASCULAR SMOOTH MUSCLE;

EID: 0034019913     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06344.x     Document Type: Conference Paper

References (20)

1. 1. WISNIEWSKI, H.M., J. WEGIEL, K.C. WANG, M. KUJAWA & B. LACH. 1989. Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can. J. Neurol. Sci. 16: 535-542.
2. 2. WISNIEWSKI, H.M., J. WEGIEL, K.C. WANG & B. LACH. 1992. Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease. Acta Neuropathol. 84: 117-127.
3. 3. WISNIEWSKI, H.M., A.B. JOHNSON, C.S. RAINE, W.J. KAY & R.D. TERRY. 1970. Senile plaques and cerebral amyloidosis in aged dogs. A histochemical and ultrastructural study. Lab. Invest. 23: 287-296.
4. 4. ISHII, T. 1958. Histochemistry of the senile changes of the brain of the senile dementia. Psychiatr. Neurol. Jpn. 60: 768-781.
5. 5. ISHII, T. 1969. Enzyme histochemical studies of senile plaques and the plaque-like degeneration of arteries and capillaries (Scholz). Acta Neuropathol. (Berl.) 14: 250-260.
6. 6. MIYAKAWA, T. 1986. The relationship between amyloid fibrils around cerebral blood vessels and senile plaques, and ultrastructure of amyloid fibrils. International Symposium on Dementia and Amyloid. Neuropathology (Suppl.) 3: 37-48.
7. 7. MIYAKAWA, T., A. SHIMOJI, R. KUMAMOTO & Y. HIGUCHI. 1982. The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia. Morphological mechanism of senile plaque production. Virchows Arch. B 40: 121-129.
8. 8. KAWAI, M., R.N. KALARIA, S.I. HARIK & G. PERRY. 1990. The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am. J. Pathol. 137: 1435-1446.
9. 9. MANDYBUR, T.I. 1986. Cerebral amyloid angiopathy: the vascular pathology and complications. J. Neuropathol. Exp. Neurol. 45: 79-90.
10. 10. WISNIEWSKI, H.M., J. FRACKOWIAK, A. ZOLTOWSKA & K.S. KIM. 1994. Vascular β-amyloid in Alzheimer's disease angiopathy is produced by proliferating and degenerating smooth muscle cells. Amyloid: Int. J. Exp. Clin. Invest. 1: 8-16.
11. 11. WEGIEL, J., H.M. WISNIEWSKI, I. KUCHNA, M. TARNAWSKI, E. POPOVITCH, J. KULCZYCKI, W.K. DOWJAT & T. WISNIEWSKI. 1998. Cell-type specific enhancement of amyloid-β deposition in a novel presenilin-1 mutation (P117L). J. Neuropathol. Exp. Neurol. 57: 831-838.
12. 12. FRACKOWIAK, J., B. MAZUR-KOLECKA, J. WEGIEL, K.S. KIM & H.M. WISNIEWSKI. 1995. Culture of canine vascular myocytes as a model to study production and accumulation of β-protein by cells involved in amyloidogenesis. In Research Advances in Alzheimer's Disease and Related Disorders. K. Iqbal, J.A. Mortimer, B. Winblad & H.M. Wisniewski, Eds.: 747-754. J. Wiley & Sons. Chichester, England.
13. 13. FRACKOWIAK, J., B. MAZUR-KOLECKA, H.M. WISNIEWSKI, A. POTEMPSKA, R.T. CARROLL, M.R. EMMERLING & K.S. KIM. 1995. Secretion and accumulation of Alzheimer β-protein by cultured vascular smooth muscle cells from old and young dogs. Brain Res. 676: 225-230.
14. 14. MAZUR-KOLECKA, B., J. FRACKOWIAK, R.T. CARROLL & H.M. WISNIEWSKI. 1997. Accumulation of Alzheimer amyloid-β peptide in cultured myocytes is enhanced by serum and reduced by cerebrospinal fluid. J. Neuropathol. Exp. Neurol. 56: 263-272.
15. 15. WISNIEWSKI, H.M., J. FRACKOWIAK & B. MAZUR-KOLECKA. 1995. In vitro production of β-amyloid in smooth muscle cells isolated from amyloid angiopathy-affected vessels. Neurosci. Lett. 183: 120-123.
16. 16. FRACKOWIAK, J., B. MAZUR-KOLECKA, R.T. CARROLL, A. CHAUHAN & H.M. WISNIEWSKI. 1997. Factors secreted by activated microglia and monocytes reduce amyloidogenesis in vascular smooth muscle cells. NeuroReport 8: 2259-2263.
17. 17. MAZUR-KOLECKA, J. FRACKOWIAK, J. KRZESLOWSKA, N. RAMAKRISHNA, T. HASKE, M. EMMERLING, W. ZHANG, K.S. KIM & H.M. WISNIEWSKI. 1999. Apolipoprotein E alters metabolism of AβPP in cells engaged in β-amyloidosis. J. Neuropathol. Exp. Neurol. 58: 288-295.
18. 18. MAZUR-KOLECKA, B., J. FRACKOWIAK & H.M. WISNIEWSKI. 1995. Apolipoproteins E3 and E4 induce, and transthyretin prevents accumulation of the Alzheimer's β-amyloid peptide in cultured vascular smooth muscle cells. Brain Res. 698: 217-222.
19. 19. MAZUR-KOLECKA, B., J. FRACKOWIAK, H. LE VINE III, T. HASKE & H.M. WISNIEWSKI. 1997. Factors produced by activated macrophages reduce accumulation of Alzheimer's β-amyloid protein in vascular smooth muscle cells. Brain Res. 760: 255-260.
20. 20. WISNIEWSKI, H.M., A.W. VORBRODT & J. WEGIEL. 1997. Amyloid angiopathy and blood-brain barrier changes in Alzheimer's disease. Ann. N.Y. Acad. Sci. 826: 161-172.