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Volumn 8, Issue 2, 2006, Pages 133-143

An overview of the genetics of substance use disorders

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE RECEPTOR; METHADONE; OPIATE RECEPTOR;

EID: 33645558987     PISSN: 15233812     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11920-006-0013-3     Document Type: Review
Times cited : (27)

References (71)
  • 1
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: Uncovering the genes
    • Goldman D, Oroszi G, Ducci F: The genetics of addictions: uncovering the genes. Nat Rev Genet 2005, 6:521-532.
    • (2005) Nat Rev Genet , vol.6 , pp. 521-532
    • Goldman, D.1    Oroszi, G.2    Ducci, F.3
  • 2
    • 27644458794 scopus 로고    scopus 로고
    • Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction
    • Kreek MJ, Nielsen DA, Butelman ER, Laforge KS: Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nat Neuroscience 2005, 8:1450-1457.
    • (2005) Nat Neuroscience , vol.8 , pp. 1450-1457
    • Kreek, M.J.1    Nielsen, D.A.2    Butelman, E.R.3    Laforge, K.S.4
  • 3
    • 0028817727 scopus 로고
    • Adoption study demonstrating two genetic pathways to drug abuse
    • Caderet RJ, Yates WR, Troughton E, et al.: Adoption study demonstrating two genetic pathways to drug abuse. Arch Gen Psychiatry 1995, 52:42-52.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 42-52
    • Caderet, R.J.1    Yates, W.R.2    Troughton, E.3
  • 4
    • 0029027001 scopus 로고
    • Common genetic mechanisms in alcohol, drug and mental disorder comorbidity
    • Pickens SW, Svikis DS, McCue M, LaBuda M: Common genetic mechanisms in alcohol, drug and mental disorder comorbidity. Drug Alcohol Dep 1995, 39:129-138.
    • (1995) Drug Alcohol Dep , vol.39 , pp. 129-138
    • Pickens, S.W.1    Svikis, D.S.2    McCue, M.3    LaBuda, M.4
  • 5
    • 0029763154 scopus 로고    scopus 로고
    • Genetic influences on DSM-III-R drug abuse and dependence: A study of 3,372 twin pairs
    • Tsuang MT, Lyons MJ, Eisen SA, et al.: Genetic influences on DSM-III-R drug abuse and dependence: a study of 3,372 twin pairs. Am J Med Genet (Neuropsychiat Genet) 1996, 67:473-477.
    • (1996) Am J Med Genet (Neuropsychiat Genet) , vol.67 , pp. 473-477
    • Tsuang, M.T.1    Lyons, M.J.2    Eisen, S.A.3
  • 6
    • 0031791365 scopus 로고    scopus 로고
    • Familial transmission of substance dependence: Alcohol, marijuana, cocaine, and habitual smoking: A report from the Collaborative Study on the Genetics of Alcoholism
    • Bierut LJ, Dinwiddie SH, Begleiter H, et al.: Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Arch Gen Psychiatry 1998, 55:982-988.
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 982-988
    • Bierut, L.J.1    Dinwiddie, S.H.2    Begleiter, H.3
  • 7
    • 10444266005 scopus 로고    scopus 로고
    • Molecular genetics of substance abuse vulnerability: Remarkable recent convergence of genome scan results
    • Uhl GR: Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results. Ann NY Acad Sci 2004, 1025:1-13.
    • (2004) Ann NY Acad Sci , vol.1025 , pp. 1-13
    • Uhl, G.R.1
  • 8
    • 0025335596 scopus 로고
    • Heritability of substance abuse and antisocial behavior: A study of monozygotic twins reared apart
    • Grove W, Eckert E, Heston L, et al.: Heritability of substance abuse and antisocial behavior: a study of monozygotic twins reared apart. Biol Psychiatry 1990, 27:1293-1304.
    • (1990) Biol Psychiatry , vol.27 , pp. 1293-1304
    • Grove, W.1    Eckert, E.2    Heston, L.3
  • 9
    • 0032213002 scopus 로고    scopus 로고
    • Genetic and environmental influences on drug use and abuse/dependence in male and female twins
    • van den Bree MB, Johnson EO, Neale MC, Pickens RW: Genetic and environmental influences on drug use and abuse/dependence in male and female twins. Drug Alcohol Depend 1998, 52:231-241.
    • (1998) Drug Alcohol Depend , vol.52 , pp. 231-241
    • van den Bree, M.B.1    Johnson, E.O.2    Neale, M.C.3    Pickens, R.W.4
  • 10
    • 0031057732 scopus 로고    scopus 로고
    • Heavy consumption of cigarettes, alcohol and coffee in male twins
    • Swan GE, Carmelli D, Cardon LR: Heavy consumption of cigarettes, alcohol and coffee in male twins. J Stud Alcohol 1997, 58:182-190.
    • (1997) J Stud Alcohol , vol.58 , pp. 182-190
    • Swan, G.E.1    Carmelli, D.2    Cardon, L.R.3
  • 11
    • 17344367165 scopus 로고    scopus 로고
    • Co-occurrence of abuse of different drugs in men: The role of drug-specific and shared vulnerabilities
    • Tsuang MT, Lyons MJ, Meyer JM, et al.: Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch Gen Psych 1998, 55:967-972.
    • (1998) Arch Gen Psych , vol.55 , pp. 967-972
    • Tsuang, M.T.1    Lyons, M.J.2    Meyer, J.M.3
  • 12
    • 0038811920 scopus 로고    scopus 로고
    • Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins
    • Kendler KS, Jacobson KC, Prescott CA, Neale MC: Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins. Am J Psychiatry 2003, 160:687-695.
    • (2003) Am J Psychiatry , vol.160 , pp. 687-695
    • Kendler, K.S.1    Jacobson, K.C.2    Prescott, C.A.3    Neale, M.C.4
  • 13
    • 27644454004 scopus 로고    scopus 로고
    • Is there a common molecular pathway for addiction?
    • Nesler EJ: Is there a common molecular pathway for addiction? Nat Neurosci 2005, 8:1445-1449.
    • (2005) Nat Neurosci , vol.8 , pp. 1445-1449
    • Nesler, E.J.1
  • 14
    • 0036135360 scopus 로고    scopus 로고
    • HPA axis function and drug addictive behaviors: Insights from studies with Lewis and Fischer 344 inbred rats
    • [review]
    • Kosten TA, Ambrosio E: HPA axis function and drug addictive behaviors: insights from studies with Lewis and Fischer 344 inbred rats [review]. Psychoneuroendocrinology 2002, 27:35-69.
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 35-69
    • Kosten, T.A.1    Ambrosio, E.2
  • 15
    • 0037086995 scopus 로고    scopus 로고
    • Rat strain differences in nicotine self-administration using an unlimited access paradigm
    • Brower VG, Fu Y, Matta SG, Sharp BM: Rat strain differences in nicotine self-administration using an unlimited access paradigm. Brain Res 2002, 930:12-20.
    • (2002) Brain Res , vol.930 , pp. 12-20
    • Brower, V.G.1    Fu, Y.2    Matta, S.G.3    Sharp, B.M.4
  • 16
    • 0142209375 scopus 로고    scopus 로고
    • Genomic priorities and public health
    • Merikangas KR, Risch N: Genomic priorities and public health. Science 2003, 302:599-601.
    • (2003) Science , vol.302 , pp. 599-601
    • Merikangas, K.R.1    Risch, N.2
  • 17
    • 6344269536 scopus 로고    scopus 로고
    • Role of DRD3 in morphine-induced conditioned place preference using drd3-knockout mice
    • Frances H, Le Foll B, Diaz J, et al.: Role of DRD3 in morphine-induced conditioned place preference using drd3-knockout mice. Neuroreport 2004, 15:2245-2249.
    • (2004) Neuroreport , vol.15 , pp. 2245-2249
    • Frances, H.1    Le Foll, B.2    Diaz, J.3
  • 18
    • 0030843574 scopus 로고    scopus 로고
    • Absence of opiate rewarding effects in mice lacking dopamine D2 receptors
    • Maldonado R, Saiardi A, Valverde O, et al.: Absence of opiate rewarding effects in mice lacking dopamine D2 receptors. Nature 1997, 388:586-589.
    • (1997) Nature , vol.388 , pp. 586-589
    • Maldonado, R.1    Saiardi, A.2    Valverde, O.3
  • 19
    • 0029852678 scopus 로고    scopus 로고
    • Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
    • Matthes HW, Maldonado R, Simonin F, et al.: Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 1996, 383:819-823.
    • (1996) Nature , vol.383 , pp. 819-823
    • Matthes, H.W.1    Maldonado, R.2    Simonin, F.3
  • 20
    • 33645579342 scopus 로고    scopus 로고
    • Admixture-matched case-control study: A practical approach for genetic association studies in admixed populations
    • Tsai HJ, Kho JY, Shaikh N, et al.: Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet 2005, 5:1-14.
    • (2005) Hum Genet , vol.5 , pp. 1-14
    • Tsai, H.J.1    Kho, J.Y.2    Shaikh, N.3
  • 21
    • 0025275767 scopus 로고
    • Allelic association of human dopamine D2 receptor gene in alcoholism
    • Blum K, Noble EP, Sheridan PJ, et al.: Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA 1990, 263:2055-2060.
    • (1990) JAMA , vol.263 , pp. 2055-2060
    • Blum, K.1    Noble, E.P.2    Sheridan, P.J.3
  • 22
    • 0036605273 scopus 로고    scopus 로고
    • Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample
    • Xu K, Liu XH, Nagarajan S, et al.: Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample. Am J Med Genet 2002, 110:45-50.
    • (2002) Am J Med Genet , vol.110 , pp. 45-50
    • Xu, K.1    Liu, X.H.2    Nagarajan, S.3
  • 23
    • 0031937745 scopus 로고    scopus 로고
    • Insertion/deletion variant (-141C Ins/Del) in the 5′ regulatory region of the dopamine D2 receptor gene: Lack of association with schizophrenia and bipolar affective disorder
    • Stober G, Jatzke S, Heils A, et al.: Insertion/deletion variant (-141C Ins/Del) in the 5′ regulatory region of the dopamine D2 receptor gene: lack of association with schizophrenia and bipolar affective disorder. J Neural Transm 1998, 105:101-109.
    • (1998) J Neural Transm , vol.105 , pp. 101-109
    • Stober, G.1    Jatzke, S.2    Heils, A.3
  • 24
    • 0034640687 scopus 로고    scopus 로고
    • Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism
    • Parsian A, Cloninger CR, Zhang ZH: Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism. Am J Med Genet 2000, 96:407-411.
    • (2000) Am J Med Genet , vol.96 , pp. 407-411
    • Parsian, A.1    Cloninger, C.R.2    Zhang, Z.H.3
  • 25
    • 0037041339 scopus 로고    scopus 로고
    • Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A)gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects
    • Li T, Liu X, Zhao J, et al.: Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A)gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects. Am J Med Genet 2002, 114:329-335.
    • (2002) Am J Med Genet , vol.114 , pp. 329-335
    • Li, T.1    Liu, X.2    Zhao, J.3
  • 26
    • 2942525904 scopus 로고    scopus 로고
    • Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations
    • Xu K, Lichtermann D, Lipsky RH, et al.: Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. Arch Gen Psychiatry 2004, 61:597-606.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 597-606
    • Xu, K.1    Lichtermann, D.2    Lipsky, R.H.3
  • 27
    • 0028042409 scopus 로고
    • Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia
    • Gelernter J, Kranzler HR, Satel SL, Rao PA: Genetic association between dopamine transporter protein alleles and cocaine-induced paranoia. Neuropsychopharmacology 1994, 11:195-200.
    • (1994) Neuropsychopharmacology , vol.11 , pp. 195-200
    • Gelernter, J.1    Kranzler, H.R.2    Satel, S.L.3    Rao, P.A.4
  • 28
    • 0037387291 scopus 로고    scopus 로고
    • Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese males
    • Hong CJ, Cheng CY, Shu LR, et al.: Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese males. J Neural Transm 2003, 110:345-351.
    • (2003) J Neural Transm , vol.110 , pp. 345-351
    • Hong, C.J.1    Cheng, C.Y.2    Shu, L.R.3
  • 29
    • 10744226608 scopus 로고    scopus 로고
    • Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis
    • Ujike H, Harano M, Inada T, et al.: Nine- or fewer repeat alleles in VNTR polymorphism of the dopamine transporter gene is a strong risk factor for prolonged methamphetamine psychosis. Pharmacogenomics J 2003, 3:242-247.
    • (2003) Pharmacogenomics J , vol.3 , pp. 242-247
    • Ujike, H.1    Harano, M.2    Inada, T.3
  • 30
    • 4344650975 scopus 로고    scopus 로고
    • Human genetics of plasma dopamine beta-hydroxylase activity: Applications to research in psychiatry and neurology
    • Cubells JF, Zabetian CP: Human genetics of plasma dopamine beta-hydroxylase activity: applications to research in psychiatry and neurology. Psychopharmacology (Berl) 2004, 174:463-476.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 463-476
    • Cubells, J.F.1    Zabetian, C.P.2
  • 31
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison PJ, Weinberger DR: Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry 2005, 10:40-68.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 33
    • 0033009868 scopus 로고    scopus 로고
    • Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism
    • Tiihonen J, Hallikainen T, Lachman HM, et al.: Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism. Mol Psychiatry 1999, 4:286-289.
    • (1999) Mol Psychiatry , vol.4 , pp. 286-289
    • Tiihonen, J.1    Hallikainen, T.2    Lachman, H.M.3
  • 34
    • 0004600232 scopus 로고    scopus 로고
    • Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early onset alcoholism associated with severe antisocial behavior
    • Hallikainen T, Lachman H, Saito T, et al.: Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early onset alcoholism associated with severe antisocial behavior. Am J Med Genet 2000, 96:348-352.
    • (2000) Am J Med Genet , vol.96 , pp. 348-352
    • Hallikainen, T.1    Lachman, H.2    Saito, T.3
  • 35
    • 0034626405 scopus 로고    scopus 로고
    • Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study
    • Horowitz R, Kotler M, Shufman E, et al.: Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study. Am J Med Genet 2000, 96:599-603.
    • (2000) Am J Med Genet , vol.96 , pp. 599-603
    • Horowitz, R.1    Kotler, M.2    Shufman, E.3
  • 36
    • 3343003563 scopus 로고    scopus 로고
    • Association analysis of the DRD4 and COMT genes in methamphetamine abuse
    • Li T, Chen CK, Hu X, et al.: Association analysis of the DRD4 and COMT genes in methamphetamine abuse. Am J Med Genet B Neuropsychiatr Genet 2004, 129:120-124.
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.129 , pp. 120-124
    • Li, T.1    Chen, C.K.2    Hu, X.3
  • 37
    • 0035133132 scopus 로고    scopus 로고
    • Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach
    • Wang T, Franke P, Neidt H, et al.: Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach. Mol Psychiatry 2001, 6:109-111.
    • (2001) Mol Psychiatry , vol.6 , pp. 109-111
    • Wang, T.1    Franke, P.2    Neidt, H.3
  • 38
    • 0033380102 scopus 로고    scopus 로고
    • Association study between high and low activity polymorphism of catechol-O-methyltransferase gene and alcoholism
    • Ishiguro H, Haruo Shibuya T, Toru M, et al.: Association study between high and low activity polymorphism of catechol-O-methyltransferase gene and alcoholism. Psychiatr Genet 1999, 9:135-138.
    • (1999) Psychiatr Genet , vol.9 , pp. 135-138
    • Ishiguro, H.1    Haruo Shibuya, T.2    Toru, M.3
  • 39
    • 7344262909 scopus 로고    scopus 로고
    • Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence
    • Duaux E, Gorwood P, Griffon N, et al.: Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence. Mol Psychiatry 1999, 3:333-336.
    • (1999) Mol Psychiatry , vol.3 , pp. 333-336
    • Duaux, E.1    Gorwood, P.2    Griffon, N.3
  • 40
    • 0032730338 scopus 로고    scopus 로고
    • Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence
    • Comings DE, Gonzalez N, Wu S, et al.: Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence. Mol Psychiatry 1999, 4:484-487.
    • (1999) Mol Psychiatry , vol.4 , pp. 484-487
    • Comings, D.E.1    Gonzalez, N.2    Wu, S.3
  • 41
    • 0037041339 scopus 로고    scopus 로고
    • Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A) gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects
    • Li T, Liu X, Zhao J, et al.: Allelic association analysis of the dopamine D2, D3, 5-HT2A, and GABA(A) gamma2 receptors and serotonin transporter genes with heroin abuse in Chinese subjects. Am J Med Genet 2002, 114:329-335.
    • (2002) Am J Med Genet , vol.114 , pp. 329-335
    • Li, T.1    Liu, X.2    Zhao, J.3
  • 42
    • 12344265724 scopus 로고    scopus 로고
    • Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden
    • Bart G, Kreek MJ, Ott J, et al.: Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology 2005, 30:417-422.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 417-422
    • Bart, G.1    Kreek, M.J.2    Ott, J.3
  • 43
    • 0027989690 scopus 로고
    • Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains
    • Berrettini WH, Ferraro TN, Alexander RC, et al.: Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains. Nat Genet 1994, 7:54-58.
    • (1994) Nat Genet , vol.7 , pp. 54-58
    • Berrettini, W.H.1    Ferraro, T.N.2    Alexander, R.C.3
  • 44
    • 13144261678 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
    • Bond C, LaForge KS, Tian M, et al.: Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A 1998, 95:9608-9613.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9608-9613
    • Bond, C.1    LaForge, K.S.2    Tian, M.3
  • 45
    • 0035826743 scopus 로고    scopus 로고
    • Association between mu opioid receptor gene polymorphisms and Chinese heroin addicts
    • Szeto CY, Tang NL, Lee DT, Stadlin A: Association between mu opioid receptor gene polymorphisms and Chinese heroin addicts. Neuroreport 2001, 12:1103-1106.
    • (2001) Neuroreport , vol.12 , pp. 1103-1106
    • Szeto, C.Y.1    Tang, N.L.2    Lee, D.T.3    Stadlin, A.4
  • 46
    • 3042781389 scopus 로고    scopus 로고
    • Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden
    • Bart G, Heilig M, LaForge KS, et al.: Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Mol Psychiatry 2004, 9:547-549.
    • (2004) Mol Psychiatry , vol.9 , pp. 547-549
    • Bart, G.1    Heilig, M.2    LaForge, K.S.3
  • 47
    • 0041331546 scopus 로고    scopus 로고
    • A genetic association study of the mu opioid receptor and severe opioid dependence
    • Crowley JJ, Oslin DW, Patkar AA, et al.: A genetic association study of the mu opioid receptor and severe opioid dependence. Psychiatr Genet 2003, 13:169-173.
    • (2003) Psychiatr Genet , vol.13 , pp. 169-173
    • Crowley, J.J.1    Oslin, D.W.2    Patkar, A.A.3
  • 48
    • 0036548042 scopus 로고    scopus 로고
    • Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin
    • Shi J, Hui L, Xu Y, et al.: Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin. Hum Mutat 2002, 19:459-460.
    • (2002) Hum Mutat , vol.19 , pp. 459-460
    • Shi, J.1    Hui, L.2    Xu, Y.3
  • 49
    • 0038755197 scopus 로고    scopus 로고
    • Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1)
    • Hernandez-Avila CA, Wand G, Luo X, et al.: Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1). Am J Med Genet (Neuropsychiatr Genet) 2003, 118:60-65.
    • (2003) Am J Med Genet (Neuropsychiatr Genet) , vol.118 , pp. 60-65
    • Hernandez-Avila, C.A.1    Wand, G.2    Luo, X.3
  • 50
    • 0036149110 scopus 로고    scopus 로고
    • The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade
    • Wand GS, McCaul M, Yang X, et al.: The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade. Neuropsychopharmacology 2002, 26:106-114.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 106-114
    • Wand, G.S.1    McCaul, M.2    Yang, X.3
  • 51
    • 0041383898 scopus 로고    scopus 로고
    • A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients
    • Oslin DW, Berrettini W, Kranzler HR, et al.: A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology 2003, 28:1546-1552.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1546-1552
    • Oslin, D.W.1    Berrettini, W.2    Kranzler, H.R.3
  • 52
    • 11144235902 scopus 로고    scopus 로고
    • Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction
    • Yuferov V, Fussell D, LaForge KS, et al.: Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics 2004, 14:793-804.
    • (2004) Pharmacogenetics , vol.14 , pp. 793-804
    • Yuferov, V.1    Fussell, D.2    LaForge, K.S.3
  • 53
    • 0030853018 scopus 로고    scopus 로고
    • Association between a delta opioid receptor gene polymorphism and heroin dependence in man
    • Mayer P, Rochlitz H, Rauch E, et al.: Association between a delta opioid receptor gene polymorphism and heroin dependence in man. Neuroreport 1997, 8:2547-2550.
    • (1997) Neuroreport , vol.8 , pp. 2547-2550
    • Mayer, P.1    Rochlitz, H.2    Rauch, E.3
  • 54
    • 0036605273 scopus 로고    scopus 로고
    • Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample
    • Xu K, Liu XH, Nagarajan S, et al.: Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample. Am J Med Genet 2002, 110:45-50.
    • (2002) Am J Med Genet , vol.110 , pp. 45-50
    • Xu, K.1    Liu, X.H.2    Nagarajan, S.3
  • 55
    • 0033528793 scopus 로고    scopus 로고
    • The proenkephalin gene (PENK) and opioid dependence
    • Comings DE, Blake H, Dietz G, et al.: The proenkephalin gene (PENK) and opioid dependence. Neuroreport 1999, 10:1133-1135.
    • (1999) Neuroreport , vol.10 , pp. 1133-1135
    • Comings, D.E.1    Blake, H.2    Dietz, G.3
  • 56
    • 0033954670 scopus 로고    scopus 로고
    • An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression
    • Zimprich A, Kraus J, Woltje M, et al.: An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression. J Neurochem 2000, 74:472-477.
    • (2000) J Neurochem , vol.74 , pp. 472-477
    • Zimprich, A.1    Kraus, J.2    Woltje, M.3
  • 57
    • 0037042097 scopus 로고    scopus 로고
    • Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse
    • Chen AC, LaForge KS, Ho A, et al.: Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse. Am J Med Genet 2002, 114:429-435.
    • (2002) Am J Med Genet , vol.114 , pp. 429-435
    • Chen, A.C.1    LaForge, K.S.2    Ho, A.3
  • 58
    • 33645573483 scopus 로고    scopus 로고
    • A functional prodynorphin promoter polymorphism and opioid dependence
    • Ray R, Doyle GA, Crowley JJ, et al.: A functional prodynorphin promoter polymorphism and opioid dependence. Psychiatr Genet 2005, 15:295-298.
    • (2005) Psychiatr Genet , vol.15 , pp. 295-298
    • Ray, R.1    Doyle, G.A.2    Crowley, J.J.3
  • 59
    • 0042852196 scopus 로고    scopus 로고
    • The Collaborative Study on the Genetics of Alcoholism: An update
    • Edenberg HJ: The Collaborative Study on the Genetics of Alcoholism: an update. Alcohol Res Health 2002, 26:214-218.
    • (2002) Alcohol Res Health , vol.26 , pp. 214-218
    • Edenberg, H.J.1
  • 60
    • 84872249295 scopus 로고    scopus 로고
    • A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population
    • Li MD, Ma JZ, Cheng R, et al.: A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet 2003, 4 Suppl 1:S103.
    • (2003) BMC Genet , vol.4 , Issue.SUPPL. 1
    • Li, M.D.1    Ma, J.Z.2    Cheng, R.3
  • 61
    • 21444445695 scopus 로고    scopus 로고
    • Genomewide linkage scan for cocaine dependence and related traits: Significant linkages for a cocaine-related trait and cocaine-induced paranoia
    • Gelernter J, Panhuysen C, Weiss R, et al.: Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet (Neuropsychiat Genet) 2005, 136:45-52.
    • (2005) Am J Med Genet (Neuropsychiat Genet) , vol.136 , pp. 45-52
    • Gelernter, J.1    Panhuysen, C.2    Weiss, R.3
  • 62
    • 12144288685 scopus 로고    scopus 로고
    • Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations
    • Edenberg HJ, Dick DM, Xuei X, et al.: Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 2004, 74:705-714.
    • (2004) Am J Hum Genet , vol.74 , pp. 705-714
    • Edenberg, H.J.1    Dick, D.M.2    Xuei, X.3
  • 64
    • 17644405816 scopus 로고    scopus 로고
    • Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence
    • Beuten J, Ma JZ, Payne TJ, et al.: Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet 2005, 76:859-864.
    • (2005) Am J Hum Genet , vol.76 , pp. 859-864
    • Beuten, J.1    Ma, J.Z.2    Payne, T.J.3
  • 65
    • 18144427933 scopus 로고    scopus 로고
    • Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence
    • Li MD, Beuten J, Ma JZ, et al.: Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet 2005, 14:1211-1219.
    • (2005) Hum Mol Genet , vol.14 , pp. 1211-1219
    • Li, M.D.1    Beuten, J.2    Ma, J.Z.3
  • 66
    • 0035209299 scopus 로고    scopus 로고
    • Polysubstance abuse-vulnerability genes: Genome scans for association, using 1,004 subects and 1,494 single-nucleotide polymorphisms
    • Uhl GR, Liu QR, Walther D, et al.: Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subects and 1,494 single-nucleotide polymorphisms. Am J Hum Genet 2001, 69:1290-1300.
    • (2001) Am J Hum Genet , vol.69 , pp. 1290-1300
    • Uhl, G.R.1    Liu, Q.R.2    Walther, D.3
  • 67
    • 23844536467 scopus 로고    scopus 로고
    • Pooled association genome scanning: Validation and use to identify addiction vulnerability loci in two samples
    • Liu QR, Drgon T, Walther D, et al.: Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples. Proc Natl Acad Sci U S A 2005, 102:11864-11869.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11864-11869
    • Liu, Q.R.1    Drgon, T.2    Walther, D.3
  • 68
    • 0021070198 scopus 로고
    • Brain opiates and neuroendocrine function
    • Grossman A: Brain opiates and neuroendocrine function. Clin Endocrinol Metab 1983, 12:725-746.
    • (1983) Clin Endocrinol Metab , vol.12 , pp. 725-746
    • Grossman, A.1
  • 69
    • 0035072912 scopus 로고    scopus 로고
    • Endomorphins and activation of the hypothalamo-pituitary-adrenal axis
    • Coventry TL, Jessop DS, Finn DP, et al.: Endomorphins and activation of the hypothalamo-pituitary-adrenal axis. J Endocrinol 2001, 169:185-193.
    • (2001) J Endocrinol , vol.169 , pp. 185-193
    • Coventry, T.L.1    Jessop, D.S.2    Finn, D.P.3
  • 70
    • 4444332549 scopus 로고    scopus 로고
    • Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects
    • Shirayama Y, Ishida H, Iwata M, et al.: Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects. J Neurochem 2004, 90:1258-1268.
    • (2004) J Neurochem , vol.90 , pp. 1258-1268
    • Shirayama, Y.1    Ishida, H.2    Iwata, M.3
  • 71
    • 12344262873 scopus 로고    scopus 로고
    • Stress-induced modulation of NK activity during influenza viral infection: Role of glucocorticoids and opioids
    • Tseng RJ, Padgett DA, Dhabhar FS, et al.: Stress-induced modulation of NK activity during influenza viral infection: role of glucocorticoids and opioids. Brain Behav Immun 2005, 19:153-164.
    • (2005) Brain Behav Immun , vol.19 , pp. 153-164
    • Tseng, R.J.1    Padgett, D.A.2    Dhabhar, F.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.