-
1
-
-
0036719212
-
Pharmacotherapy of addictions
-
Kreek, M.J., LaForge, K.S. & Butelman, E. Pharmacotherapy of addictions. Nat. Rev. Drug Discov. 1, 710-726 (2002).
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 710-726
-
-
Kreek, M.J.1
LaForge, K.S.2
Butelman, E.3
-
2
-
-
14144253824
-
Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments
-
Kreek, M.J., Bart, G., Lilly, C., LaForge, K.S. & Nielsen, D.A. Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol. Rev. 57, 1-26 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 1-26
-
-
Kreek, M.J.1
Bart, G.2
Lilly, C.3
LaForge, K.S.4
Nielsen, D.A.5
-
3
-
-
0031578941
-
Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains
-
Kosten, T.A. et al. Miserendino, M.J. & Haile, C.N., DeCaprio, J.L., Jatlow, P.I., Nestler, E.J. Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains. Brain Res. 778, 418-429 (1997).
-
(1997)
Brain Res.
, vol.778
, pp. 418-429
-
-
Kosten, T.A.1
Miserendino, M.J.2
Haile, C.N.3
DeCaprio, J.L.4
Jatlow, P.I.5
Nestler, E.J.6
-
4
-
-
17344367165
-
Co-occurrence of abuse of different drugs in men: The role of drug-specific and shared vulnerabilities
-
Tsuang, M.T. et al. Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch. Gen. Psychiatry 55, 967-972 (1998).
-
(1998)
Arch. Gen. Psychiatry
, vol.55
, pp. 967-972
-
-
Tsuang, M.T.1
-
5
-
-
0038811920
-
Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins
-
Kendler, K.S., Jacobson, K.C., Prescott, C.A. & Neale, M.C. Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins. Am. J. Psychiatry 160, 687-695 (2003).
-
(2003)
Am. J. Psychiatry
, vol.160
, pp. 687-695
-
-
Kendler, K.S.1
Jacobson, K.C.2
Prescott, C.A.3
Neale, M.C.4
-
6
-
-
0033513473
-
Genetic and environmental influences on transitions in drug use
-
Tsuang, M.T. et al. Genetic and environmental influences on transitions in drug use. Behav. Genet. 29, 473-479 (1999).
-
(1999)
Behav. Genet.
, vol.29
, pp. 473-479
-
-
Tsuang, M.T.1
-
7
-
-
0033868423
-
Alcoholism susceptibility loci: Confirmation studies in a replicate sample and further mapping
-
Foroud, T. et al. Alcoholism susceptibility loci: Confirmation studies in a replicate sample and further mapping. Alcohol. Clin. Exp. Res. 24, 933-945 (2000).
-
(2000)
Alcohol. Clin. Exp. Res.
, vol.24
, pp. 933-945
-
-
Foroud, T.1
-
8
-
-
12144288685
-
A receptor, are associated with alcohol dependence and with brain oscillations in the beta frequency
-
A receptor, are associated with alcohol dependence and with brain oscillations in the beta frequency. Am. J. Hum. Genet. 74, 705-714 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 705-714
-
-
Edenberg, H.J.1
-
9
-
-
4544236290
-
Evidence of common and specific genetic effects: Association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome
-
Wang, J.C. et al. Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Hum. Mol. Genet. 13, 1903-1911 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1903-1911
-
-
Wang, J.C.1
-
10
-
-
19944365879
-
Issues in association analysis: Error control in case-control association studies for disease gene discovery
-
Ott, J. Issues in association analysis: error control in case-control association studies for disease gene discovery. Hum. Hered. 58, 171-174 (2004).
-
(2004)
Hum. Hered.
, vol.58
, pp. 171-174
-
-
Ott, J.1
-
11
-
-
1642299385
-
Genes associated with addiction: Alcoholism, opiate and cocaine addiction
-
Kreek, M.J., Nielsen, D.A. & LaForge, K.S. Genes associated with addiction: alcoholism, opiate and cocaine addiction. Neuromolecular Med. 5, 85-108 (2004).
-
(2004)
Neuromolecular Med.
, vol.5
, pp. 85-108
-
-
Kreek, M.J.1
Nielsen, D.A.2
LaForge, K.S.3
-
12
-
-
0031872284
-
A tryptophan hydroxylase gene marker for suicidality and alcoholism
-
Nielsen, D.A. et al. A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch. Gen. Psychiatry 55, 593-602 (1998).
-
(1998)
Arch. Gen. Psychiatry
, vol.55
, pp. 593-602
-
-
Nielsen, D.A.1
-
13
-
-
0028267462
-
Familial correlates of reduced central serotonergic system function in patients with personality disorders
-
Coccaro, E.F. et al. Familial correlates of reduced central serotonergic system function in patients with personality disorders. Arch. Gen. Psychiatry 51, 318-324 (1994).
-
(1994)
Arch. Gen. Psychiatry
, vol.51
, pp. 318-324
-
-
Coccaro, E.F.1
-
14
-
-
0028117344
-
Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism
-
Nielsen, D.A. et al. Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism. Arch. Gen. Psychiatry 51, 34-38 (1994).
-
(1994)
Arch. Gen. Psychiatry
, vol.51
, pp. 34-38
-
-
Nielsen, D.A.1
-
15
-
-
20344399125
-
Association between dopamine receptor D3 gene Ball polymorphism and cognitive impulsiveness in alcohol-dependent men
-
Limosin, F. et al. Association between dopamine receptor D3 gene Ball polymorphism and cognitive impulsiveness in alcohol-dependent men. Eur. Psychiatry 20, 304-306 (2005).
-
(2005)
Eur. Psychiatry
, vol.20
, pp. 304-306
-
-
Limosin, F.1
-
16
-
-
17944377117
-
Dopamine D4 receptor gene (DRD4) is associated with novelty seeking (NS) and substance abuse: The saga continues
-
Lusher, J.M., Chandler, C. & Ball, D. Dopamine D4 receptor gene (DRD4) is associated with novelty seeking (NS) and substance abuse: the saga continues. Mol. Psychiatry 6, 497-499 (2001).
-
(2001)
Mol. Psychiatry
, vol.6
, pp. 497-499
-
-
Lusher, J.M.1
Chandler, C.2
Ball, D.3
-
17
-
-
0037043754
-
DRD4 and novelty seeking: Results of meta-analyses
-
Schinka, J.A., Letsch, E.A. & Crawford, F.C. DRD4 and novelty seeking: results of meta-analyses. Am. J. Med. Genet. B Neuropsychiatr. For. Genet. 114, 643-648 (2002).
-
(2002)
Am. J. Med. Genet. B Neuropsychiatr. For. Genet.
, vol.114
, pp. 643-648
-
-
Schinka, J.A.1
Letsch, E.A.2
Crawford, F.C.3
-
19
-
-
0027450927
-
Substance abuse vulnerability and D2 receptor genes
-
Uhl, G., Blum, K., Noble, E. & Smith, S. Substance abuse vulnerability and D2 receptor genes. Trends Neurosci. 16, 83-88 (1993).
-
(1993)
Trends Neurosci.
, vol.16
, pp. 83-88
-
-
Uhl, G.1
Blum, K.2
Noble, E.3
Smith, S.4
-
20
-
-
0027339609
-
The A1 allele at the D2 dopamine receptor gene and alcoholism: A reappraisal
-
Gelernter, J., Goldman, D. & Risch, N. The A1 allele at the D2 dopamine receptor gene and alcoholism: a reappraisal. J. Am. Med. Assoc. 269, 1673-1677 (1993).
-
(1993)
J. Am. Med. Assoc.
, vol.269
, pp. 1673-1677
-
-
Gelernter, J.1
Goldman, D.2
Risch, N.3
-
21
-
-
2642572803
-
Identification and characterization of ANKK1: A novel kinase gene closely linked to DRD2 on chromosome band 11q23.1
-
Neville, M.J., Johnstone, E.C. & Walton, R.T. Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum. Mutat. 23, 540-545 (2004).
-
(2004)
Hum. Mutat.
, vol.23
, pp. 540-545
-
-
Neville, M.J.1
Johnstone, E.C.2
Walton, R.T.3
-
22
-
-
0020084326
-
Diagnosis and symptoms of depression in opiate addicts. Course and relationship to treatment outcome
-
Rounsaville, B.J., Weissman, M.M., Crits-Christoph, K., Wilber, C. & Kleber, H. Diagnosis and symptoms of depression in opiate addicts. Course and relationship to treatment outcome. Arch. Gen. Psychiatry 39, 151-156 (1982).
-
(1982)
Arch. Gen. Psychiatry
, vol.39
, pp. 151-156
-
-
Rounsaville, B.J.1
Weissman, M.M.2
Crits-Christoph, K.3
Wilber, C.4
Kleber, H.5
-
23
-
-
0028931920
-
Attention deficit hyperactivity disorder and substance abuse: Relationships and implications for treatment
-
Levin, F. & Kleber, H. Attention deficit hyperactivity disorder and substance abuse: relationships and implications for treatment. Harv. Rev. Psychiatry 2, 246-258 (1995).
-
(1995)
Harv. Rev. Psychiatry
, vol.2
, pp. 246-258
-
-
Levin, F.1
Kleber, H.2
-
25
-
-
0030179225
-
Opiates, opioids and addiction
-
Kreek, M.J. Opiates, opioids and addiction. Mol. Psychiatry 1, 232-254 (1996).
-
(1996)
Mol. Psychiatry
, vol.1
, pp. 232-254
-
-
Kreek, M.J.1
-
26
-
-
0035085721
-
Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction
-
Schluger, J.H., Borg, L., Ho, A. & Kreek, M.J. Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction. Neuropsychopharmacology 24, 568-575 (2001).
-
(2001)
Neuropsychopharmacology
, vol.24
, pp. 568-575
-
-
Schluger, J.H.1
Borg, L.2
Ho, A.3
Kreek, M.J.4
-
27
-
-
0036181179
-
Naltrexone decreases craving and alcohol self-administration in alcohol dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis
-
O'Malley, S.S., Krishnan-Sarin, S., Farren, C., Sinha, R. & Kreek, M.J. Naltrexone decreases craving and alcohol self-administration in alcohol dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis. Psychopharmacology (Berl.) 160, 19-29 (2002).
-
(2002)
Psychopharmacology (Berl.)
, vol.160
, pp. 19-29
-
-
O'Malley, S.S.1
Krishnan-Sarin, S.2
Farren, C.3
Sinha, R.4
Kreek, M.J.5
-
28
-
-
0030431223
-
Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during 'binge'-pattern cocaine administration and chronic withdrawal
-
Zhou, Y. et al. Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during 'binge'-pattern cocaine administration and chronic withdrawal. J. Pharmacol. Exp. Ther. 279, 351-358 (1996).
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 351-358
-
-
Zhou, Y.1
-
29
-
-
0242490815
-
Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states
-
Sinha, R. et al. Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states. Psychopharmacology (Berl.) 170, 62-72 (2003).
-
(2003)
Psychopharmacology (Berl.)
, vol.170
, pp. 62-72
-
-
Sinha, R.1
-
30
-
-
13144261678
-
Single nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
-
Bond, C. et al. Single nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction. Proc. Natl. Acad. Sci. USA 95, 9608-9613 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9608-9613
-
-
Bond, C.1
-
31
-
-
0034723054
-
Opioid receptor and peptide gene polymorphisms: Potential implications for addictions
-
LaForge, K.S., Yuferov, V. & Kreek, M.J. Opioid receptor and peptide gene polymorphisms: potential implications for addictions. Eur. J. Pharmacol. 410, 249-268 (2000).
-
(2000)
Eur. J. Pharmacol.
, vol.410
, pp. 249-268
-
-
LaForge, K.S.1
Yuferov, V.2
Kreek, M.J.3
-
32
-
-
3042781389
-
Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden
-
Bart, G. et al. Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Mol. Psychiatry 9, 547-549 (2004).
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 547-549
-
-
Bart, G.1
-
33
-
-
12344265724
-
Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden
-
Bart, G. et al. Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology 30, 417-422 (2005).
-
(2005)
Neuropsychopharmacology
, vol.30
, pp. 417-422
-
-
Bart, G.1
-
34
-
-
0030004521
-
Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders
-
Lachman, H.M. et al. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6, 243-250 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 243-250
-
-
Lachman, H.M.1
-
35
-
-
0347052803
-
Catechol-O-methyltransferase polymorphism alters hypothalamic-pituitary- adrenal axis responses to naloxone: A preliminary report
-
Oswald, L.M., McCaul, M., Choi, L., Yang, X. & Wand, G.S. Catechol-O-methyltransferase polymorphism alters hypothalamic-pituitary-adrenal axis responses to naloxone: a preliminary report. Biol. Psychiatry 55, 102-105 (2004).
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 102-105
-
-
Oswald, L.M.1
McCaul, M.2
Choi, L.3
Yang, X.4
Wand, G.S.5
-
36
-
-
0037008485
-
Role of genotype in the cycle of violence in maltreated children
-
Caspi, A. et al. Role of genotype in the cycle of violence in maltreated children. Science 297, 851-854 (2002).
-
(2002)
Science
, vol.297
, pp. 851-854
-
-
Caspi, A.1
-
37
-
-
0037624040
-
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
-
Caspi, A., Sugden, K. & Moffitt, T.E. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389 (2003).
-
(2003)
Science
, vol.301
, pp. 386-389
-
-
Caspi, A.1
Sugden, K.2
Moffitt, T.E.3
-
38
-
-
12344328265
-
An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk
-
Hu, X. et al. An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol. Clin. Exp. Res. 29, 8-16 (2005).
-
(2005)
Alcohol. Clin. Exp. Res.
, vol.29
, pp. 8-16
-
-
Hu, X.1
-
39
-
-
21444445695
-
Genomewide linkage scan for cocaine dependence and related traits: Significant linkages for a cocaine-related trait and cocaine-induced paranoia
-
Gelernter, J. et al. Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am. J. Med. Genet. B Neuropsychiatr. For. Genet. 136, 45-52 (2005).
-
(2005)
Am. J. Med. Genet. B Neuropsychiatr. For. Genet.
, vol.136
, pp. 45-52
-
-
Gelernter, J.1
-
40
-
-
0036683617
-
Substance abuse vulnerability loci: Converging genome scanning data
-
Uhl, G.R., Liu, Q.R. & Naiman, D. Substance abuse vulnerability loci: converging genome scanning data. Trends Genet. 18, 420-425(2002).
-
(2002)
Trends Genet.
, vol.18
, pp. 420-425
-
-
Uhl, G.R.1
Liu, Q.R.2
Naiman, D.3
-
41
-
-
10444266005
-
Molecular genetics of substance abuse vulnerability: Remarkable recent convergence of genome scan results
-
Uhl, G. Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results. Ann. NY Acad. Sci. 1025, 1-13 (2004).
-
(2004)
Ann. NY Acad. Sci.
, vol.1025
, pp. 1-13
-
-
Uhl, G.1
-
42
-
-
11144235902
-
Redefinition of the human kappa opioid receptor (OPRK1) structure and association of haplotypes with opiate addiction
-
Yuferov, V. et al. Redefinition of the human kappa opioid receptor (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics 14, 793-804 (2004).
-
(2004)
Pharmacogenetics
, vol.14
, pp. 793-804
-
-
Yuferov, V.1
-
43
-
-
0030836682
-
High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers
-
Vandenbergh, D.J., Rodriguez, L.A., Miller, I.T., Uhl, G.R. & Lachman, H.M. High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers. Am. J. Med. Genet. 74, 439-442 (1997).
-
(1997)
Am. J. Med. Genet.
, vol.74
, pp. 439-442
-
-
Vandenbergh, D.J.1
Rodriguez, L.A.2
Miller, I.T.3
Uhl, G.R.4
Lachman, H.M.5
-
44
-
-
0034626405
-
Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study
-
Horowitz, R. et al. Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study. Am. J. Med. Genet. 96, 599-603 (2000).
-
(2000)
Am. J. Med. Genet.
, vol.96
, pp. 599-603
-
-
Horowitz, R.1
-
45
-
-
3343003563
-
Association analysis of the DRD4 and COMT genes in methamphetamine abuse
-
Li, T. et al. Association analysis of the DRD4 and COMT genes in methamphetamine abuse. Am. J. Med. Genet. B Neuropsychiatr. For. Genet. 129, 120-124 (2004).
-
(2004)
Am. J. Med. Genet. B Neuropsychiatr. For. Genet.
, vol.129
, pp. 120-124
-
-
Li, T.1
-
46
-
-
0033966753
-
A haplotype at DBH, associated with low plasma dopamine-β- hydroxylase activity, also associates with cocaine-induced paranoia
-
Cubells, J.F. et al. A haplotype at DBH, associated with low plasma dopamine-β-hydroxylase activity, also associates with cocaine-induced paranoia. Mol. Psychiatry 5, 56-63 (2000).
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 56-63
-
-
Cubells, J.F.1
-
47
-
-
0030946048
-
Cannabinoid receptor gene (CNR1): Association with IV drug use
-
Comings, D.E. et al. Cannabinoid receptor gene (CNR1): Association with IV drug use. Mol. Psychiatry 2, 161-168 (1997).
-
(1997)
Mol. Psychiatry
, vol.2
, pp. 161-168
-
-
Comings, D.E.1
-
48
-
-
0036472003
-
Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence
-
Schmidt, L.G. et al. Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence. Drug Alcohol Depend. 65, 221-224 (2002).
-
(2002)
Drug Alcohol Depend.
, vol.65
, pp. 221-224
-
-
Schmidt, L.G.1
-
49
-
-
6044253601
-
Human cannabinoid receptor 1:5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse
-
Zhang, P-W. et al. Human cannabinoid receptor 1:5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Mol. Psychiatry 9, 916-931 (2004).
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 916-931
-
-
Zhang, P.-W.1
-
50
-
-
0037062436
-
A missense mutation in human fatty acid amide hydrolase associated with problem drug use
-
Sipe, J.C., Chiang, K., Gerber, A.L., Beutler, E. & Cravatt, B.F. A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Proc. Natl. Acad. Sci. USA 99, 8394-8399 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8394-8399
-
-
Sipe, J.C.1
Chiang, K.2
Gerber, A.L.3
Beutler, E.4
Cravatt, B.F.5
|