Nanoprecipitation versus emulsion-based techniques or the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues

AAPS PharmSciTech

Volumn 6, Issue 4, 2005, Pages

  Bilati, Ugo ^a   Allémann, Eric ^a,b   Doelker, Eric ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Bracco Suisse SA   (Switzerland)

Author keywords

Double emulsion; Entrapment efficiency; MALDI TOF MS; Nanoparticles; Nanoprecipation; Protein

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONE; ALCOHOL; DICHLOROMETHANE; DIMER; DIMETHYL SULFOXIDE; INSULIN; LYSOZYME; NANOPARTICLE; ORGANIC SOLVENT; POLYGLACTIN; POLYLACTIC ACID; SURFACTANT; TETANUS TOXOID; WATER; NANOMATERIAL; PROTEIN;

ANTIGENICITY; ARTICLE; BIODEGRADATION; DRUG DETERMINATION; DRUG STABILITY; EMULSION; ENCAPSULATION; EVAPORATION; HYDROPHOBICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PARTICLE SIZE; PROTEIN STABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRASOUND; ANIMAL; BIODEGRADABLE IMPLANT; CHEMISTRY; COMPARATIVE STUDY; DRUG FORMULATION; HUMAN; METHODOLOGY; PHARMACEUTICS; PRECIPITATION; SWINE; SYNTHESIS;

ABSORBABLE IMPLANTS; ANIMALS; DRUG COMPOUNDING; DRUG STABILITY; EMULSIONS; HUMANS; NANOSTRUCTURES; PRECIPITATION; PROTEINS; SWINE; TECHNOLOGY, PHARMACEUTICAL;

EID: 33645512835     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060474     Document Type: Article

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