Determination of protein loading in biodegradable polymer microspheres containing tetanus toxoid

Vaccine

Volumn 15, Issue 6-7, 1997, Pages 672-678

  Gupta, Rajesh K ^a,b   Chang, An Cheng ^a,c   Griffin, Paul ^a   Rivera, Rachel ^a   Guo, Yu Yi ^a   Siber, George R ^a,d  

^a State Laboratory Institute   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c CURIS INC   (United States)

^d PFIZER INC   (United States)

Author keywords

acid or base hydrolysis; extraction methods; loading determination; microspheres; ninhydrin assay; tetanus toxoid

Indexed keywords

CHLOROFORM; DICHLOROMETHANE; DIMETHYL SULFOXIDE; MICROSPHERE; POLYGLACTIN; POLYLACTIC ACID; TETANUS TOXOID;

ARTICLE; BIODEGRADATION; COLORIMETRY; DRUG UPTAKE; EXTRACTION; FREEZE DRYING; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE DIAGNOSIS; RELIABILITY; TETANUS;

ANTIGENS, BACTERIAL; BIODEGRADATION, ENVIRONMENTAL; DRUG DELIVERY SYSTEMS; EVALUATION STUDIES; HYDROCHLORIC ACID; LACTIC ACID; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; QUINOLINES; SODIUM HYDROXIDE; SOLVENTS; SURFACE-ACTIVE AGENTS; TETANUS TOXOID;

EID: 0030900314     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00233-2     Document Type: Article

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