T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells

Blood

Volumn 107, Issue 7, 2006, Pages 2797-2805

  Matsuda, Jennifer L ^b   Zhang, Qianjun ^b   Ndonye, Rachel ^b   Richardson, Stewart K ^b   Howell, Amy R ^b   Gapin, Laurent ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR T BET;

ANIMAL EXPERIMENT; ARTICLE; CELL MATURATION; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; IN VITRO STUDY; MICROARRAY ANALYSIS; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

EID: 33645505137     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-08-3103     Document Type: Article

References (53)

1. Kronenberg M. Toward an understanding of NKT-cell biology: progress and paradoxes. Annu Rev Immunol. 2005; 23:877-900.
2. - T cells in mice and humans. J Exp Med. 1994;180:1097-1106.
3. Kronenberg M, Gapin L. The unconventional lifestyle of NKT cells. Nat Rev Immunol. 2002;2:557-568.
4. Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L. NKT cells: what's in a name? Nat Rev Immunol. 2004;4:231-237.
5. Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annu Rev Immunol. 2004;22:817-890.
6. Gapin L, Matsuda JL, Surh CD, Kronenberg M. NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol. 2001;2:971-978.
7. Benlagha K, Kyin T, Beavis A, Teyton L, Bendelac A. A thymic precursor to the NKT-cell lineage. Science. 2002;296:553-555.
8. + CD1d-dependent precursor stage. J Exp Med. 2002;195:835-844.
9. Gadue P, Stein PL. NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. J Immunol. 2002;169:2397-2406.
10. Dao T, Guo D, Ploss A, et al. Development of CD1d-restricted NKT cells in the mouse thymus. Eur J Immunol. 2004;34:3542-3552.
11. Bezbradica JS, Hill T, Stanic AK, Van Kaer L, Joyce S. Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny. Proc Natl Acad Sci U S A. 2005;102:5114-5119.
12. Egawa T, Eberl G, Taniuchi I, et al. Genetic evidence supporting selection of the Vα14i NKT-cell lineage from double-positive thymocyte precursors. Immunity. 2005;22:705-716.
13. Matsuda JL, Gapin L. Developmental program of mouse Vα14i NKT cells. Curr Opin Immunol. 2005;17:122-130.
14. Matsuda JL, Gapin L, Sidobre S, et al. Homeostasis of Vα14i NKT cells. Nat Immunol. 2002;3:966-974.
15. Loza MJ, Perussia B. Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation? Nat Immunol. 2001;2:917-924.
16. Townsend MJ, Weinmann AS, Matsuda JL, et al. T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells. Immunity. 2004;20:477-494.
17. Szabo SJ, Sullivan BM, Stemmann C, Satoskar AR, Sleckman BP, Glimcher LH. Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells. Science. 2002;295:338-342.
18. Matsuda JL, Naidenko OV, Gapin L, et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med. 2000;192:741-754.
19. Grogan JL, Mohrs M, Harmon B, Lacy DA, Sedat JW, Locksley RM. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity. 2001;14:205-215.
20. Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000;100:655-669.
21. Mullen AC, Hutchins AS, High FA, et al. Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat Immunol. 2002;3:652-658.
22. + T cell function by the transcription factor Eomesodermin. Science. 2003;302:1041-1043.
23. Hermans IF, Silk JD, Yang J, et al. The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo. J Immunol Methods. 2004;285:25-40.
24. Kim S, Iizuka K, Kang HS, et al. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol. 2002;3:523-528.
25. Papaioannou VE, Silver LM. The T-box gene family. Bioessays. 1998;20:9-19.
26. Kennedy J, Vicari AP, Saylor V, et al. A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J Leukoc Biol. 2000;67:725-734.
27. + T cells to the spleen during the generation of regulatory T cells in tolerance. J Immunol. 2002;169:31-38.
28. Thomas SY, Hou R, Boyson JE, et al. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. J Immunol. 2003;171:2571-2580.
29. Johnston B, Kim CH, Soler D, Emoto M, Butcher EC. Differential chemokine responses and homing patterns of murine TCR αβ NKT-cell subsets. J Immunol. 2003;171:2960-2969.
30. Unutmaz D, Xiang W, Sunshine MJ, Campbell J, Butcher E, Littman DR. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. J Immunol. 2000;165:3284-3292.
31. + NKT cells patrolling liver sinusoids. PLoS Biol. 2005;3:e113.
32. Matsuda JL, Gapin L, Fazilleau N, Warren K, Naidenko OV, Kronenberg M. Natural killer T cells reactive to a single glycolipid exhibit a highly diverse T cell receptor β repertoire and small clone size. Proc Natl Acad Sci U S A. 2001;98:12636-12641.
33. Mempel M, Ronet C, Suarez F, et al. Natural killer T cells restricted by the monomorphic MHC class 1b CD1d1 molecules behave like inflammatory cells. J Immunol. 2002;168:365-371.
34. + thymocyte population associated with intact Fas antigen expression on the target. J Exp Med. 1994;180:423-432.
35. Kawano T, Cui J, Koezuka Y, et al. Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells. Proc Natl Acad Sci U S A. 1998;95:5690-5693.
36. + V alpha 24 NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. 2001;97:2067-2074.
37. Yokoyama WM, Kim S, French AR. The dynamic life of natural killer cells. Annu Rev Immunol. 2004;22:405-429.
38. Kaech SM, Hemby S, Kersh E, Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell. 2002;111:837-851.
39. Lu B, Zagouras P, Fischer JE, Lu J, Li B, Flavell RA. Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation. Proc Natl Acad Sci U S A. 2004;101:3023-3028.
40. Glimcher LH, Townsend MJ, Sullivan BM, Lord GM. Recent developments in the transcriptional regulation of cytolytic effector cells. Nat Rev Immunol. 2004;4:900-911.
41. Wei DG, Lee H, Park SH, et al. Expansion and long-range differentiation of the NKT-cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med. 2005;202:239-248.
42. McNab FW, Berzins SP, Pellicci DG, et al. The influence of CD1d in postselection NKT-cell maturation and homeostasis. J Immunol. 2005;175:3762-3768.
43. Ranson T, Vosshenrich CA, Corcuff E, et al. IL-15 availability conditions homeostasis of peripheral natural killer T cells. Proc Natl Acad Sci U S A. 2003;100:2663-2668.
44. Perera LP, Goldman CK, Waldmann TA. IL-15 induces the expression of chemokines and their receptors in T lymphocytes. J Immunol. 1999;162:2606-2612.
45. Kawamura T, Koka R, Ma A, Kumar V. Differential roles for IL-15R α-chain in NK cell development and Ly-49 induction. J Immunol. 2003;171:5085-5090.
46. Shnyreva M, Weaver WM, Blanchette M, et al. Evolutionarily conserved sequence elements that positively regulate IFN-γ expression in T cells. Proc Natl Acad Sci U S A. 2004;101:12622-12627.
47. Tong Y, Aune T, Boothby M. T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-γ promoter via a conserved T-box half-site. Proc Natl Acad Sci U S A. 2005;102:2034-2039.
48. Stetson DB, Mohrs M, Reinhardt RL, et al. Constitutive cytokine mRNAs mark natural killer (NK) and NKT cells poised for rapid effector function. J Exp Med. 2003;198:1069-1076.
49. Tato CM, Martins GA, High FA, DiCioccio CB, Reiner SL, Hunter CA. Cutting Edge: Innate production of IFN-γ by NK cells is independent of epigenetic modification of the IFN-γ promoter. J Immunol. 2004;173:1514-1517.
50. Bonecchi R, Bianchi G, Bordignon PP, et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med. 1998;187:129-134.
51. Roberts AI, Devadas S, Zhang X, et al. The role of activation-induced cell death in the differentiation of T-helper-cell subsets. Immunol Res. 2003;28:285-293.
52. Zhang S, Lukacs NW, Lawless VA, Kunkel SL, Kaplan MH. Cutting edge: differential expression of chemokines in Th1 and Th2 cells is dependent on Stat6 but not Stat4. J Immunol. 2000;165:10-14.
53. Lametschwandtner G, Biedermann T, Schwarzler C, et al. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities. J Allergy Clin Immunol. 2004;113:987-994.