The influence of CD1d in postselection NKT cell maturation and homeostasis

Journal of Immunology

Volumn 175, Issue 6, 2005, Pages 3762-3768

  McNab, Finlay W ^a   Berzins, Stuart P ^a   Pellicci, Daniel G ^a   Kyparissoudis, Konstantinos ^a   Field, Kenneth ^a   Smytli, Mark J ^b   Godfrey, Dale I ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD1D ANTIGEN; CD69 ANTIGEN; LEUKOCYTE ANTIGEN; NK1.1 ANTIGEN; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CELL SELECTION; CELL SURVIVAL; CONTROLLED STUDY; HOMEOSTASIS; LYMPHOCYTE PROLIFERATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS;

EID: 24744450763     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.6.3762     Document Type: Article

References (41)

1. Bendelac, A. 1995. Positive selection of mouse NK1T cells by CD1-expressing cortical thymocytes. J. Exp. Med. 182: 2091-2096.
2. + cells. J. Immunol 164: 2412-2418.
3. Gapin, L., J. L. Matsuda, C. D. Surh, and M. Kronenberg. 2001. NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat. Immunol. 2: 971-978.
4. + CD1d-dependent precursor stage. J. Exp. Med. 195: 835-844.
5. Benlagha, K., T. Kyin, A. Beavis, L. Teyton, and A. Bendelac. 2002. A thymic precursor to the NK T cell lineage. Science 296: 553-555.
6. Gadue, P., and P. L. Stein. 2002. NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. J. Immunol. 169: 2397-2406.
7. Kronenberg, M. 2005. Toward an understanding of NKT cell biology: progress and paradoxes. Annu. Rev. Immunol. 23: 877-900.
8. Wilson, S. B., and T. L. Delovitch. 2003. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat. Rev. Immunol 3: 211-222.
9. Godfrey, D. I., and M. Kronenberg. 2004. Going both ways: immune regulation via CD1d-dependent NKT cells. J. Clin. Invest. 114: 1379-1388.
10. Brigl, M., and M. B. Brenner. 2004. CD1: Antigen presentation and T cell function. Annu. Rev. Immunol. 22: 817-890.
11. Matsuda, J. L., and L. Gapin. 2005. Developmental program of mouse Vα14i NKT cells. Curr. Opin. Immunol. 17: 122-130.
12. Berzins, S. P., A. P. Uldrich, D. G. Pellicci, F. McNab, Y. Hayakawa, M. J. Smyth, and D. I. Godfrey. 2004. Parallels and distinctions between T and NKT cell development in the thymus. Immunol. Cell Biol. 82: 269-275.
13. Smyth, M. J., N. Y. Crowe, Y. Hayakawa, K. Takeda, H. Yagita, and D. I. Godfrey. 2002. NKT cells: conductors of tumor immunity? Curr. Opin. Immunol. 14: 165-171.
14. Stanic, A. K., J. S. Bezbradica, J. J. Park, N. Matsuki, A. L. Mora, L. Van Kaer, M. R. Boothby, and S. Joyce. 2004. NF-κB controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes. J. Immunol. 172: 2265-2273.
15. Sivakumar, V., K. J. Hammond, N. Howells, K. Pfeffer, and F. Weih. 2003. Differential requirement for Rel/nuclear factor κB family members in natural killer T cell development. J. Exp. Med. 197: 1613-1621.
16. Matsuda, J. L., L. Gapin, S. Sidobre, W. C. Kieper, J. Y. T. Tan, R. Ceredig, C. D. Surh, and M. Kronenberg. 2002. Homeostasis of Vα14i NKT cells. Nat. Immunol. 3: 966-974.
17. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J. Exp. Med. 187: 1047-1056.
18. - T-cell deficiency and Iddm in Nod/Lt mice. Diabetes 46: 572-582.
19. Lehuen, A., O. Lantz, L. Beaudoin, V. Laloux, C. Carnaud, A. Bendelac, J. F. Bach, and R. C. Monteiro. 1998. Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 188: 1831-1839.
20. Hammond, K. J., D. G. Pellicci, L. D. Poulton, O. V. Naidenko, A. A. Scalzo, A. G. Baxter, and D. I. Godfrey. 2001. CD1d-restricted NKT cells: an interstrain comparison. J. Immunol. 167: 1164-1173.
21. + T lymphocytes. Science 268: 863-865.
22. Mendiratta, S. K., W. D. Martin, S. Hong, A. Boesteanu, S. Joyce, and L. Van Kaer. 1997. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6: 469-477.
23. + T cell development and early IL-4 production in CD1-deficient mice. Immunity 6: 459-467.
24. Smiley, S. T., M. H. Kaplan, and M. J. Grusby. 1997. Immunoglobulin E production in the absence of interleukin-4-secreting Cd1-dependent cells. Science 275: 977-979.
25. + NKT cells in germ-free mice. Eur. J. Immunol. 30: 620-625.
26. Godfrey, D. I., K. J. Hammond, L. D. Poulton, M. J. Smyth, and A. G. Baxter. 2000. NKT cells: facts, functions and fallacies. Immunol Today 21: 573-583.
27. + NKT lymphocytes are activated memory cells. Eur. J. Immunol. 30: 1544-1550.
28. van Der Vliet, H. J., N. Nishi, T. D. de Gruijl, B. M. von Blomberg, A. J. van den Eertwegh, H. M. Pinedo, G. Giaccone, and R. J. Scheper. 2000. Human natural killer T cells acquire a memory-activated phenotype before birth. Blood 95: 2440-2442.
29. Matsuda, J. L., O. V. Naidenko, L. Gapin, T. Nakayama, M. Taniguchi, C. R. Wang, Y. Koezuka, and M. Kronenberg. 2000. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192: 741-754.
30. Berzins, S. P., R. L. Boyd, and J. F. Miller. 1998. The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool. J. Exp. Med. 187: 1839-1848.
31. Scollay, R. G., E. C. Butcher, and I. L. Weissman. 1980. Thymus cell migration: quantitative aspects of cellular traffic from the thymus to the periphery in mice. Eur. J. Immunol. 10: 210-218.
32. Benlagha, K., A. Weiss, A. Beavis, L. Teyton, and A. Bendelac. 2000. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. Med. 191: 1895-1903.
33. Michie, S. A., E. A. Kirkpatrick, and R. V. Rouse. 1988. Rare peripheral T cells migrate to and persist in normal mouse thymus. J. Exp. Med. 168: 1929-1934.
34. Agus, D. B., C. D. Surh, and J. Sprent. 1991. Reentry of T cells to the adult thymus is restricted to activated T cells. J. Exp. Med. 173: 1039-1046.
35. Berzins, S. P., K. Kyparissoudis, D. G. Pellicci, K. J. Hammond, S. Sidobre, A. Baxter, M. J. Smyth, M. Kronenberg, and D. I. Godfrey. 2004. Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies. Immunol. Cell Biol. 82: 247-252.
36. Park, S. H., A. Weiss, K. Benlagha, T. Kyin, L. Teyton, and A. Bendelac. 2001. The mouse CD1d-restricted repertoire is dominated by a few autoreactive T cell receptor families. J. Exp. Med. 193: 893-904.
37. Hammond, K. J., and M. Kronenberg. 2003. Natural killer T cells: natural or unnatural regulators of autoimmunity? Curr. Opin. Immunol. 15: 683-689.
38. Van Kaer, L. 2005. α-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat. Rev. Immunol. 5: 31-42.
39. Zhou, D., C. Cantu III, Y. Sagiv, N. Schrantz, A. B. Kulkarni, X. Qi, D. J. Mahuran, C. R. Morales, G. A. Grabowski, K. Benlagha, et al. 2004. Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins. Science 303: 523-527.
40. Godfrey, D. I., D. G. Pellicci, and M. J. Smyth. 2004. Immunology: the elusive NKT cell antigen-is the search over? Science 306: 1687-1689.
41. Mattner, J., K. L. Debord, N. Ismail, R. D. Goff, C. Cantu III, D. Zhou, P. Saint-Mezard, V. Wang, Y. Gao, N. Yin, et al. 2005. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434: 525-529.