Characterization of human liver cytochrome P450 enzymes involved in the metabolism of rutaecarpine

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 1, 2006, Pages 304-309

  Lee, Sang Kyu ^a   Lee, Jung Hwa ^b   Yoo, Hye Hyun ^b   Kim, Dong Hyun ^b   Jahng, Yurngdong ^a   Jeong, Tae Cheon ^a  

^a Yeungnam University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Human liver microsomes; LC ESI MS; Rutaecarpine

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; CYTOCHROME P450 INHIBITOR; DRUG METABOLITE; ENZYME ANTIBODY; ISOENZYME; KETOCONAZOLE; LIVER ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RUTAECARPINE;

ARTICLE; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME ANALYSIS; HUMAN; LIVER MICROSOME; LYMPHOBLASTOID CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ALKALOIDS; ANTI-INFLAMMATORY AGENTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOOXYGENASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; HUMANS; IONS; LIVER; LYMPHOCYTES; MICROSOMES, LIVER; MODELS, CHEMICAL; TECHNOLOGY, PHARMACEUTICAL;

EID: 33645078634     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2005.10.039     Document Type: Article

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