Effects of Evodia rutaecarpa and rutaecarpine on the pharmacokinetics of caffeine in rats

Planta Medica

Volumn 71, Issue 7, 2005, Pages 640-645

  Tsai, Tung Hu ^a,b   Chang, Chun Hao ^b   Lin, Lie Chwen ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Caffeine; Evodia rutaecarpa; Microdialysis; Pharmacokinetics; Rutaceae; Rutaecarpine; Traditional Chinese medicine

Indexed keywords

ALCOHOL; CAFFEINE; EVODIA FRUIT; RUTAECARPINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG EXCRETION; DRUG PENETRATION; DRUG STRUCTURE; HEPATOBILIARY SYSTEM; HERB DRUG INTERACTION; MALE; MICRODIALYSIS; NONHUMAN; RAT;

ADMINISTRATION, ORAL; ALKALOIDS; ANIMALS; AREA UNDER CURVE; BILE; BRAIN; CAFFEINE; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; EVODIA; INFUSIONS, INTRAVENOUS; MALE; PHYTOTHERAPY; PLANT EXTRACTS; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS; VASODILATOR AGENTS;

EVODIA RUTAECARPA; RUTACEAE;

EID: 23644462820     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-871270     Document Type: Article

References (23)

1. Chen L, Bondoc FY, Lee MJ, Hussin AH, Thomas PE, Yang CS. Caffeine induces cytochrome P4501A2: induction of CYP1A2 by tea in rats. Drug Metab Dispos 1996; 24: 529-33
2. Asahina Y, Kashiwaki K. 1915. Chemical constituents of the fruits of Evodia rutaecarpa. J Pharm Soc Jpn 1915; 35: 293
3. Ueng YF, Wang JJ, Lin LC, Park SS, Chen CF. Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa. Life Sci 2001; 70: 207-17
4. Tang W, Eisenbrand G. Evodia rutaecarpa (Juss) Benth, in Chinese Drugs of Plant Origin. Tang W, Eisenbrand, G, eds. Springer-Verlag, Berlin: 1992: pp 509-14
5. Kano Y, Zong Q, Komatsu K. 1991. Pharmacological properties of galenical preparation, XIV. Body temperature retaining effect of the Chinese traditional medicine, "Goshuyu-to" and component crude drugs. Chem Pharm Bull 1991; 39: 690-2
6. Tsai TH. Assaying protein unbound drugs using microdialysis techniques. J Chromatogr B 2003; 797: 161-73
7. Tsai TH, Chen YF, Chen IF, Chen CF. Measurement of unbound caffeic acid in rat blood by on-line microdialysis coupled with liquid chromatography and its application to pharmacokinetic studies. J Chromatogr B 1999; 729: 119-25
8. Tsai TH. Pharmacokinetics of pefloxacin and its interaction with cyclosporin A, a P-glycoprotein modulator, in rat blood, brain and bile, using simultaneous microdialysis. Brit J Pharmacol 2001; 132: 1310-6
9. Scott DO, Lunte CE. In vivo microdialysis sampling in the bile, blood, and liver of rats to study the disposition of phenol. Pharm Res 1993; 10: 335-42
10. Paxinos S, Watson C. The Rat Brain in Stereotaxic Coordinates. 1982 Academic Press, Sydney
11. Tsai TH, Lee CH, Yeh PH. Effect of cyclosporine, a P-glycoprotein modulator, on the disposition and biliary excretion of camptothecin using microdialysis. Brit J Pharmacol 2001; 134: 1245-52
12. Tsai TH, Liu SC, Tsai PL, Ho LK, Shum AYC, Chen CF. Pharmacokinetics of baicalein and its interaction with P-glycoprotein inhibitor, cyclosporin A, in the rat: a microdialysis study. Brit J Pharmacol 2002; 137: 1314-20
13. Tsai PL, Tsai TH. Hepatobiliary excretion of berberine. Drug Metab Dispos 2004; 32: 405-12
14. McCall AL, Millington WR, Wurtman RJ. Blood-brain barrier transport of caffeine: dose-related restriction of adenine transport. Life Sci 1982; 31: 709-15
15. Holstege A, Kurz M, Weinbeck M, Gerok W. Excretion of caffeine and its primary degradation products into bile. J Hepatol 1993; 17: 67-73
16. Beach CA, Mays DC, Sterman BM, Gerber N. Metabolism, distribution, seminal excretion and pharmacokinetics of caffeine in the rabbit. J Pharmacol Exp Ther 1985; 233: 18-23
17. Lin JH, Sugiyama Y, Awazu S, Hanano M. (1982) In vitro and in vivo evaluation of the tissue-to-blood partition coefficient for physiological pharmacokinetic models. J Pharmacokinet Biopharm 1982; 10: 637-47
18. Ueng YF, Jan WC, Chen TL, Guengerich FP, Chen CF. The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug Metab Dispos 2002; 30: 349-53
19. Ayalogu EO, Snelling J, Lewis DFV, Talwar S, Clifford MN, Ioannides C. (1995) Induction of hepatic CYP1A2 by the oral administration of caffeine to rats: lack of association with the Ah locus. Biochim Biophys Acta 1995; 1272: 89-94
20. Berthou F, Goasduff T, Dreano Y, Menez JF. Caffeine increases its own metabolism through cytochrome P4501A induction in rats. Life Sci 1995; 57: 541-9
21. Roberts EA, Furuya KN, Tang BK, Kalow W. Caffeine biotransformation in human hepatocyte lines derived from normal liver tissue. Biochem Biophy Res Commun 1994; 201: 559-66
22. Ha HR, Chen J, Krahenbuhl S, Follath F. Biotransformation of caffeine by cDNA-expressed human cytochromes P-450. Eur J Clin Pharmacol 1996; 49: 309-15
23. Ursing C, Wikner J, Brismar K, Rojdmark S. Caffeine raises the serum melatonin level in healthy subjects: an indication of melatonin metabolism by cytochrome P450(CYP)1A2. J Endocrinol Inv 2003; 26: 03-6