Identification of the microsomal oxidation metabolites of rutaecarpine, a main active alkaloid of the medicinal herb Evodia rutaecarpa

Journal of Chromatography A

Volumn 1076, Issue 1-2, 2005, Pages 103-109

  Ueng, Yune Fang ^a,d   Yu, Hsi Jung ^b   Lee, Chang Hsin ^b   Peng, Ching ^b   Jan, Woan Ching ^c   Ho, Li Kang ^c   Chen, Chieh Fu ^c   Don, Ming Jaw ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b CHINESE CULTURE UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cytochrome P450; Hydroxyrutaecarpine; Rat; Rutaecarpine

Indexed keywords

ABSORPTION; DRUG PRODUCTS; ENZYMES; LIQUID CHROMATOGRAPHY; METABOLISM; OXIDATION;

CYTOCHROMES; MICROSOMAL ENZYMES; RAT LIVER MICROSOMES; RUTAECARPINE;

METABOLITES;

10 HYDROXYRUTAECARPINE; 11 HYDROXYRUTAECARPINE; 12 HYDROXYRUTAECARPINE; 3 HYDROXYRUTAECARPINE; 3 METHYLCHOLANTHRENE; CYTOCHROME P450; DRUG METABOLITE; RUTAECARPINE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROPHOTOMETRY; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; EVODIA RUTAECARPA; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PRIORITY JOURNAL; RAT; STRUCTURE ANALYSIS;

ALKALOIDS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EVODIA; MICROSOMES, LIVER; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EVODIA; EVODIA RUTAECARPA;

EID: 19444363681     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2005.04.021     Document Type: Article

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