-
1
-
-
0037804758
-
Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: Role of Chk1 and Chk2 phosphorylation and caspase 3
-
Amico D. Barbui A.M. Erba E. Rambaldi A. Introna M. Golay J. 2003 Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3 Blood 101 4589 4597
-
(2003)
Blood
, vol.101
, pp. 4589-4597
-
-
Amico, D.1
Barbui, A.M.2
Erba, E.3
Rambaldi, A.4
Introna, M.5
Golay, J.6
-
2
-
-
0032869052
-
Antibody-targeted therapy for myeloid leukemia
-
Appelbaum F.R. 1999 Antibody-targeted therapy for myeloid leukemia Seminars in Hematology 36 2 8
-
(1999)
Seminars in Hematology
, vol.36
, pp. 2-8
-
-
Appelbaum, F.R.1
-
5
-
-
0034659745
-
Ki-4(scFv)-ETA′, a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice
-
Barth S. Huhn M. Matthey B. Tawadros S. Schnell R. Schinkothe T. Diehl V. Engert A. 2000 Ki-4(scFv)-ETA′, a new recombinant anti-CD30 immunotoxin with highly specific cytotoxic activity against disseminated Hodgkin tumors in SCID mice Blood 95 3909 3914
-
(2000)
Blood
, vol.95
, pp. 3909-3914
-
-
Barth, S.1
Huhn, M.2
Matthey, B.3
Tawadros, S.4
Schnell, R.5
Schinkothe, T.6
Diehl, V.7
Engert, A.8
-
7
-
-
0034900174
-
Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
-
Bross P.F. Beitz J. Chen G. Chen X.H. Duffy E. Kieffer L. Roy S. Sridhara R. Rahman A. Williams G. Pazdur R. 2001 Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia Clinical Cancer Research 7 1490 1496
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 1490-1496
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Chen, X.H.4
Duffy, E.5
Kieffer, L.6
Roy, S.7
Sridhara, R.8
Rahman, A.9
Williams, G.10
Pazdur, R.11
-
8
-
-
0027955656
-
Murine and humanized constructs of monoclonal antibody M195 (anti-CD33) for the therapy of acute myelogenous leukemia
-
Caron P.C. Schwartz M.A. Co M.S. Queen C. Finn R.D. Graham M.C. Divgi C.R. Larson S.M. Scheinberg D.A. 1994 Murine and humanized constructs of monoclonal antibody M195 (anti-CD33) for the therapy of acute myelogenous leukemia Cancer 73 1049 1056
-
(1994)
Cancer
, vol.73
, pp. 1049-1056
-
-
Caron, P.C.1
Schwartz, M.A.2
Co, M.S.3
Queen, C.4
Finn, R.D.5
Graham, M.C.6
Divgi, C.R.7
Larson, S.M.8
Scheinberg, D.A.9
-
10
-
-
0035874886
-
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells
-
Dorrie J. Gerauer H. Wachter Y. Zunino S.J. 2001 Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells Cancer Research 61 4731 4739
-
(2001)
Cancer Research
, vol.61
, pp. 4731-4739
-
-
Dorrie, J.1
Gerauer, H.2
Wachter, Y.3
Zunino, S.J.4
-
12
-
-
0028909393
-
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules
-
Freeman S.D. Kelm S. Barber E.K. Crocker P.R. 1995 Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules Blood 85 2005 2012
-
(1995)
Blood
, vol.85
, pp. 2005-2012
-
-
Freeman, S.D.1
Kelm, S.2
Barber, E.K.3
Crocker, P.R.4
-
13
-
-
0027502253
-
Anti-B4-blocked ricin: A phase I trial of 7-day continuous infusion in patients with B-cell neoplasms
-
Grossbard M.L. Lambert J.M. Goldmacher V.S. Spector N.L. Kinsella J. Eliseo L. Coral F. Taylor J.A. Blattler W.A. Epstein C.L. Nadler L.M. 1993 Anti-B4-blocked ricin: a phase I trial of 7-day continuous infusion in patients with B-cell neoplasms Journal of Clinical Oncology 11 726 737
-
(1993)
Journal of Clinical Oncology
, vol.11
, pp. 726-737
-
-
Grossbard, M.L.1
Lambert, J.M.2
Goldmacher, V.S.3
Spector, N.L.4
Kinsella, J.5
Eliseo, L.6
Coral, F.7
Taylor, J.A.8
Blattler, W.A.9
Epstein, C.L.10
Nadler, L.M.11
-
14
-
-
0036007596
-
Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia
-
Hamann P.R. Hinman L.M. Hollander I. Beyer C.F. Lindh D. Holcomb R. Hallett W. Tsou H.R. Upeslacis J. Shochat D. Mountain A. Flowers D.A. Bernstein I. 2002 Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia Bioconjugate Chemistry 13 47 58
-
(2002)
Bioconjugate Chemistry
, vol.13
, pp. 47-58
-
-
Hamann, P.R.1
Hinman, L.M.2
Hollander, I.3
Beyer, C.F.4
Lindh, D.5
Holcomb, R.6
Hallett, W.7
Tsou, H.R.8
Upeslacis, J.9
Shochat, D.10
Mountain, A.11
Flowers, D.A.12
Bernstein, I.13
-
16
-
-
1242352458
-
Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: Rationale for efficacy in CD33-negative malignancies with endocytic capacity
-
Jedema I. Barge R.M. van der Velden V.H. Nijmeijer B.A. van Dongen J.J. Willemze R. Falkenburg J.H. 2004a Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity Leukemia 18 316 325
-
(2004)
Leukemia
, vol.18
, pp. 316-325
-
-
Jedema, I.1
Barge, R.M.2
Van Der Velden, V.H.3
Nijmeijer, B.A.4
Van Dongen, J.J.5
Willemze, R.6
Falkenburg, J.H.7
-
17
-
-
0842287498
-
Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins
-
Jedema I. Barge R.M. Frankel A.E. Willemze R. Falkenburg J.H. 2004b Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins Experimental Hematology 32 188 194
-
(2004)
Experimental Hematology
, vol.32
, pp. 188-194
-
-
Jedema, I.1
Barge, R.M.2
Frankel, A.E.3
Willemze, R.4
Falkenburg, J.H.5
-
18
-
-
1542348477
-
Cancer statistics, 2004
-
Jemal A. Tiwari R.C. Murray T. Ghafoor A. Samuels A. Ward E. Feuer E.J. Thun M.J. 2004 Cancer statistics, 2004 CA Cancer Journal for Clinicians 54 8 29
-
(2004)
CA Cancer Journal for Clinicians
, vol.54
, pp. 8-29
-
-
Jemal, A.1
Tiwari, R.C.2
Murray, T.3
Ghafoor, A.4
Samuels, A.5
Ward, E.6
Feuer, E.J.7
Thun, M.J.8
-
21
-
-
0034001076
-
Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
-
Kreitman R.J. Wilson W.H. White J.D. Stetler-Stevenson M. Jaffe E.S. Giardina S. Waldmann T.A. Pastan I. 2000 Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies Journal of Clinical Oncology 18 1622 1636
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 1622-1636
-
-
Kreitman, R.J.1
Wilson, W.H.2
White, J.D.3
Stetler-Stevenson, M.4
Jaffe, E.S.5
Giardina, S.6
Waldmann, T.A.7
Pastan, I.8
-
23
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 680 685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
24
-
-
2342585342
-
Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts
-
Lang P. Barbin K. Feuchtinger T. Greil J. Peipp M. Zunino S.J. Pfeiffer M. Handgretinger R. Niethammer D. Fey G.H. 2004 Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts Blood 103 3982 3985
-
(2004)
Blood
, vol.103
, pp. 3982-3985
-
-
Lang, P.1
Barbin, K.2
Feuchtinger, T.3
Greil, J.4
Peipp, M.5
Zunino, S.J.6
Pfeiffer, M.7
Handgretinger, R.8
Niethammer, D.9
Fey, G.H.10
-
25
-
-
0036733277
-
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
-
Larson R.A. Boogaerts M. Estey E. Karanes C. Stadtmauer E.A. Sievers E.L. Mineur P. Bennett J.M. Berger M.S. Eten C.B. Munteanu M. Loken M.R. Van Dongen J.J. Bernstein I.D. Appelbaum F.R. 2002 Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin) Leukemia 16 1627 1636
-
(2002)
Leukemia
, vol.16
, pp. 1627-1636
-
-
Larson, R.A.1
Boogaerts, M.2
Estey, E.3
Karanes, C.4
Stadtmauer, E.A.5
Sievers, E.L.6
Mineur, P.7
Bennett, J.M.8
Berger, M.S.9
Eten, C.B.10
Munteanu, M.11
Loken, M.R.12
Van Dongen, J.J.13
Bernstein, I.D.14
Appelbaum, F.R.15
-
27
-
-
0033188326
-
Toxin entry: How bacterial proteins get into mammalian cells
-
Lord J.M. Smith D.C. Roberts L.M. 1999 Toxin entry: how bacterial proteins get into mammalian cells Cellular Microbiology 1 85 91
-
(1999)
Cellular Microbiology
, vol.1
, pp. 85-91
-
-
Lord, J.M.1
Smith, D.C.2
Roberts, L.M.3
-
29
-
-
0034904570
-
P75/AIRM1 and CD33, two sialoadhesin receptors that regulate the proliferation or the survival of normal and leukemic myeloid cells
-
Mingari M.C. Vitale C. Romagnani C. Falco M. Moretta L. 2001 p75/AIRM1 and CD33, two sialoadhesin receptors that regulate the proliferation or the survival of normal and leukemic myeloid cells Immunological Reviews 181 260 268
-
(2001)
Immunological Reviews
, vol.181
, pp. 260-268
-
-
Mingari, M.C.1
Vitale, C.2
Romagnani, C.3
Falco, M.4
Moretta, L.5
-
30
-
-
0023652396
-
A C-terminal signal prevents secretion of luminal ER proteins
-
Munro S. Pelham H.R. 1987 A C-terminal signal prevents secretion of luminal ER proteins Cell 48 899 907
-
(1987)
Cell
, vol.48
, pp. 899-907
-
-
Munro, S.1
Pelham, H.R.2
-
32
-
-
0034662163
-
Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2
-
Paul S.P. Taylor L.S. Stansbury E.K. McVicar D.W. 2000 Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2 Blood 96 483 490
-
(2000)
Blood
, vol.96
, pp. 483-490
-
-
Paul, S.P.1
Taylor, L.S.2
Stansbury, E.K.3
McVicar, D.W.4
-
33
-
-
0035342491
-
An improved procedure for the generation of recombinant single-chain Fv antibody fragments reacting with human CD13 on intact cells
-
Peipp M. Simon N. Loichinger A. Baum W. Mahr K. Zunino S.J. Fey G.H. 2001 An improved procedure for the generation of recombinant single-chain Fv antibody fragments reacting with human CD13 on intact cells Journal of Immunological Methods 251 161 176
-
(2001)
Journal of Immunological Methods
, vol.251
, pp. 161-176
-
-
Peipp, M.1
Simon, N.2
Loichinger, A.3
Baum, W.4
Mahr, K.5
Zunino, S.J.6
Fey, G.H.7
-
34
-
-
0037093199
-
A recombinant CD7-specific single-chain immunotoxin is a potent inducer of apoptosis in acute leukemic T cells
-
Peipp M. Kupers H. Saul D. Schlierf B. Greil J. Zunino S.J. Gramatzki M. Fey G.H. 2002 A recombinant CD7-specific single-chain immunotoxin is a potent inducer of apoptosis in acute leukemic T cells Cancer Research 62 2848 2855
-
(2002)
Cancer Research
, vol.62
, pp. 2848-2855
-
-
Peipp, M.1
Kupers, H.2
Saul, D.3
Schlierf, B.4
Greil, J.5
Zunino, S.J.6
Gramatzki, M.7
Fey, G.H.8
-
36
-
-
7344268577
-
Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's lymphoma
-
Schnell R. Vitetta E. Schindler J. Barth S. Winkler U. Borchmann P. Hansmann M.L. Diehl V. Ghetie V. Engert A. 1998 Clinical trials with an anti-CD25 ricin A-chain experimental and immunotoxin (RFT5-SMPT-dgA) in Hodgkin's lymphoma Leukemia and Lymphoma 30 525 537
-
(1998)
Leukemia and Lymphoma
, vol.30
, pp. 525-537
-
-
Schnell, R.1
Vitetta, E.2
Schindler, J.3
Barth, S.4
Winkler, U.5
Borchmann, P.6
Hansmann, M.L.7
Diehl, V.8
Ghetie, V.9
Engert, A.10
-
38
-
-
0035462401
-
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse
-
Sievers E.L. 2001 Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse Expert Opinion on Biological Therapy 1 893 901
-
(2001)
Expert Opinion on Biological Therapy
, vol.1
, pp. 893-901
-
-
Sievers, E.L.1
-
39
-
-
0033151526
-
Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate
-
Sievers E.L. Appelbaum F.R. Spielberger R.T. Forman S.J. Flowers D. Smith F.O. Shannon-Dorcy K. Berger M.S. Bernstein I.D. 1999 Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate Blood 93 3678 3684
-
(1999)
Blood
, vol.93
, pp. 3678-3684
-
-
Sievers, E.L.1
Appelbaum, F.R.2
Spielberger, R.T.3
Forman, S.J.4
Flowers, D.5
Smith, F.O.6
Shannon-Dorcy, K.7
Berger, M.S.8
Bernstein, I.D.9
-
40
-
-
0023691747
-
Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells
-
Simmons D. Seed B. 1988 Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells Journal of Immunology 141 2797 2800
-
(1988)
Journal of Immunology
, vol.141
, pp. 2797-2800
-
-
Simmons, D.1
Seed, B.2
-
41
-
-
0033814033
-
Use of the Strep-Tag and streptavidin for detection and purification of recombinant proteins
-
Skerra A. Schmidt T.G. 2000 Use of the Strep-Tag and streptavidin for detection and purification of recombinant proteins Methods in Enzymology 326 271 304
-
(2000)
Methods in Enzymology
, vol.326
, pp. 271-304
-
-
Skerra, A.1
Schmidt, T.G.2
-
42
-
-
10744231795
-
Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells
-
Tur M.K. Huhn M. Thepen T. Stocker M. Krohn R. Vogel S. Jost E. Osieka R. de Winkel J.G. Fischer R. Finnern R. Barth S. 2003 Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells Cancer Research 63 8414 8419
-
(2003)
Cancer Research
, vol.63
, pp. 8414-8419
-
-
Tur, M.K.1
Huhn, M.2
Thepen, T.3
Stocker, M.4
Krohn, R.5
Vogel, S.6
Jost, E.7
Osieka, R.8
De Winkel, J.G.9
Fischer, R.10
Finnern, R.11
Barth, S.12
-
43
-
-
0035874504
-
Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: In vivo and in vitro saturation and internalization by leukemic and normal myeloid cells
-
van der Velden V. te Marvelde J.G. Hoogeveen P.G. Bernstein I.D. Houtsmuller A.B. Berger M.S. 2001 Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells Blood 97 3197 3204
-
(2001)
Blood
, vol.97
, pp. 3197-3204
-
-
Van Der Velden, V.1
Te Marvelde, J.G.2
Hoogeveen, P.G.3
Bernstein, I.D.4
Houtsmuller, A.B.5
Berger, M.S.6
-
44
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
Vermes I. Haanen C. Steffens-Nakken H. Reutelingsperger C. 1995 A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V Journal of Immunological Methods 184 39 51
-
(1995)
Journal of Immunological Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
46
-
-
0028985881
-
EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins
-
Wels W. Beerli R. Hellmann P. Schmidt M. Marte B.M. Kornilova E.S. Hekele A. Mendelsohn J. Groner B. Hynes N.E. 1995 EGF receptor and p185erbB-2-specific single-chain antibody toxins differ in their cell-killing activity on tumor cells expressing both receptor proteins International Journal of Cancer 60 137 144
-
(1995)
International Journal of Cancer
, vol.60
, pp. 137-144
-
-
Wels, W.1
Beerli, R.2
Hellmann, P.3
Schmidt, M.4
Marte, B.M.5
Kornilova, E.S.6
Hekele, A.7
Mendelsohn, J.8
Groner, B.9
Hynes, N.E.10
-
47
-
-
0023820894
-
Calicheamicin gamma 1I: An antitumor antibiotic that cleaves double-stranded DNA site specifically
-
Zein N. Sinha A.M. McGahren W.J. Ellestad G.A. 1988 Calicheamicin gamma 1I: an antitumor antibiotic that cleaves double-stranded DNA site specifically Science 240 1198 1201
-
(1988)
Science
, vol.240
, pp. 1198-1201
-
-
Zein, N.1
Sinha, A.M.2
McGahren, W.J.3
Ellestad, G.A.4
|